PPT-Dosing of Drugs in Renal

Failure II Dr Haider Raheem Effect of Hemodialysis Conventional Dialysis Gentamicin GG s renal function continues to deteriorate to the extent that she requires hemodialysis What additional alterations in her gentamicin dosing regimen are necessary when she is having dialysis. Barbara Lynne Phillips, M.D.. Assistant Professor of Neurology. WSU BSOM. Disclosures. Participated in Phase II and III trials of . lacosamide. No other disclosures. Anticonvulsants. Mainstay of treatment. Josh Exley. Learning Objectives. Acute Kidney Injury. Drugs and the Kidney. Chronic Kidney Disease. Normal Kidney function. Kidney Functions. Excretory function. Filter metabolites, toxins, drugs. Homeostatic function. PCRRT London . 18. th. July 2015. Marie O. ’. Meara. Pharmacist. Honorary Clinical Lecturer Kings College London. Disclosures. . I am currently an employee of . Abbvie. Ltd, the opinions expressed throughout this presentation are my own.. Barbara Lynne Phillips, M.D.. Assistant Professor of Neurology. WSU BSOM. Disclosures. Participated in Phase II and III trials of . lacosamide. No other disclosures. Anticonvulsants. Mainstay of treatment. CRRT BackgroundWhena patient is initiated on CRRT antimicrobial therapy often requires adjustment to ensure adequate drug concentrations are achievedCVVHDremoves solutes including drugs via diffusion Senior Nursing Lecturer. BGI. Definition. . ARF Is . the rapid breakdown of renal (. kidney) function . that occurs when high levels of uremic . toxins (waste . products of the body's . metabolism) accumulate . 15.03.2020. 1. LO: please insert relevant Learning objective reference here. 2. DIURETICS. 3. Learning Objectives for Diuretics. Renal physiology:. explain the physiology of the renal system and. how drugs impact ionic composition. disese. (ESRD) posted for renal transplant and . ileal. conduit . .. Presentor. – . DR.Smruti. . Govekar. (JRIII). . Dept.of. Anaesthesiology. A 11 year old female child was referred from nephrology OPD for renal transplant surgery for pre . Pharmacokinetics. Dosage adjustment in renal impairment. Dialysis removal of drugs. Ideal drug for a renal patient. Non-renal excretion. No side effects. Active drug. No renally excreted metabolites. Nephrotoxins. are chemicals displaying nephrotoxicity.. Nephrotoxicity. Renal toxicity can be a result of hemodynamic changes, direct injury to cells and tissues, inflammatory tissue injury, obstruction of renal tubules. . 2. What is the effect of pregnancy on the kidney disease?. What is the effect of the kidney disease on pregnancy?. 3. EFFECT OF PREGNANCY ON KIDNEY DISEASE. Changes in clinical manifestations . Possible alterations in the long-term course of the disease. diuresis. ). and sodium excretion (. natriuresis. ). RENAL TRANSPORT MECHANISMS . The kidney filters plasma water and solutes at the . glomerulus. at a very high rate (180 L/day) and must recover a significant percentage of most of these substances before excretion in the urine.. Joseph McGraw, Pharm.D., M.P.H., Ph.D.. Associate Professor of Pharmaceutical Sciences . CUW School of Pharmacy . President and Chief Scientific Officer . Persotype. DX LLC. Background. Ph.D.-Biopharmaceutical Sciences. . Created by: Andrew . Fratoni. , . PharmD. IV Aminoglycosides. Gentamicin. Tobramycin*. Amikacin*. *Restricted Antibiotics. Aminoglycoside Drug . Class Principles. Good bactericidal activity against gram negative organisms.