PPT-Pharmacokinetics & Drug Dosing

Pharmacokinetics Dosage adjustment in renal impairment Dialysis removal of drugs Ideal drug for a renal patient Nonrenal excretion No side effects Active drug No renally excreted metabolites. & THERAPEUTICS . ESSENTIAL DRUG LIST . Alexandra Burke-Smith. 1. Drugs and the Autonomic Nervous System . Overview of the ANS . Sympathetic NS = “fight or flight”, Parasympathetic NS = “rest + digest”. Nancy Clark, . M.Ed. , . Director Medical Informatics Education. , M.D.. Informatics Curriculum Director Regional Campus . 2016. 1. Objectives. Find the Drug Reference Library web page. Errors. Implications for Disaster Medicine . William Fales, MD, FACEP. Michigan State University Kalamazoo Center for Medical Studies. 5. th. District Medical Response Coalition. Kalamazoo County Medical Control Authority. Properties: . Optimizing Pharmacokinetics and Safety During Drug . Discovery. ACS Short Course. Li Di and Edward H. Kerns. Introduction to Drug-Like Properties. Few research compounds will become drugs because they lack sufficient pharmacokinetics (PK) and safety. Mental picture of . what’s happening . inside…. … really might help.. Drug action (effects). Proportional to concentration at site of action. Concentration predicts better than dose. General Rules. Jessica Tagerman, . PharmD. , . RPh. Pharmacokinetics & pharmacodynamics. Pharmacodynamics: What the drug does to the body. Pharmacokinetics: What the body does to the drug. pharmacodynamics. “What the drug does to the body”. Pediatric Patients. All patients younger than16 years. Respond differently to drugs than the rest of the population. More sensitive . to drugs than other patients are. Show . greater individual . variation. BW733. October 1, 2013. Pharmacokinetics . WebQuest. 1. http://. www.speedlighter.ca/2011/12/25/why-i-shoot-stills/courtney-craig-photo-by-michael-willems. /. Overview. Introduction. Absorption. IV, . of obstetric anesthesia . Dr SPS. 10/4/2015. 1. Dr. S. Parthasarathy MD., DA., DNB, . MD (. Acu. ), Dip. . Diab. . DCA, . Dip. Software statistics, . PhD (physiology) FICA . Mahatma Gandhi Medical College and Research Institute, . CRRT BackgroundWhena patient is initiated on CRRT antimicrobial therapy often requires adjustment to ensure adequate drug concentrations are achievedCVVHDremoves solutes including drugs via diffusion and Protein Drugs . The central paradigm(. نموذج. ). of clinical pharmacology: The dose-concentration-effect relationship. Dose (mg/day) . pharmacokinetics. Concentration. (mg/l). Efficacy . Toxicity. The . use of drugs to treat psychiatric disorders is often the foundation for a successful treatment approach that can also include other types of intervention such as psychotherapy and behavior therapy. . Alobaidy. Reference text. Shargel. L., Yu AB. Applied Biopharmaceutics and Pharmacokinetics. Introduction. The . physicochemical characteristics of the active pharmaceutical . ingredient, . the dosage form . Joseph McGraw, Pharm.D., M.P.H., Ph.D.. Associate Professor of Pharmaceutical Sciences . CUW School of Pharmacy . President and Chief Scientific Officer . Persotype. DX LLC. Background. Ph.D.-Biopharmaceutical Sciences.