PPT-The Use of Bone Turnover Markers in Osteoporosis Therapy Monitoring

in Asia Pacific Dato Dr Lee JoonKiong Deputy Medical Director HOD Department of Orthopedic Surgery Beacon Hospital Malaysia Disclaimer No conflict of interest to be declared Outline Part 1. Lowell Dilworth-Chemical Pathologist. CKD. CKD and Bone disease. Mineral . metabolism controlled by kidneys. , intestine, parathyroid glands and . bone. The . kidney plays a critical role in mineral homeostasis regulation and, therefore, renal disease exerts widespread effects on the skeleton and soft . Department of Medicine. KGMU, . Lucknow. 30.07.14. OSTEOPOROSIS. A disease characterized . by low . bone . mass . (reduced bone density) and micro-architectural deterioration of . bone . tissue, leading . Overview. Definitions. Epidemiology. Symptoms . Treatment. Effects of Exercise. Testing. Prescription. Conclusion. References. http://. www.beautyhealthwomen.com. /benefits-in-women. Video. http://. www.youtube.com/watch?v=rHyeZhcoZcQ. Mahtab. . Niroomand. M.D.. Assistant Professor of Endocrinology. SBUMS. Lecture outline. Epidemiology of osteoporosis. Definition of osteoporosis. Clinical manifestations of osteoporosis. Diagnosis of osteoporosis. calcitonin. BONE REMODELING. Throughout life, bone is continuously remodeled, with about 10% of the adult skeleton replaced each year. . The purpose of bone remodeling is to remove and replace damaged bone and to maintain calcium homeostasis.. Osteoporosis. and its F. uture . M. anagement . Bagher Larijani, MD, FACE. Professor of Internal Medicine and Endocrinology. Director-General and Chief Scientific Officer. Endocrinology and Metabolism Research Institute. Treatment. . and Prevention. Nahid Rianon, . M.D., . Dr.P.H. .. The University . of Texas . Health Science Center at Houston (UTHealth). Module . 3 . of 3. LEARNING OBJECTIVES:. At the end of this presentation, attendees will be able to. Dr. . Sura. Al . Zoubi. MMS . Pharmacology. . Lecture 3. Revision. Gout. The term . gout . describes a disease spectrum including hyperuricemia, . recurrent attacks . of acute arthritis associated with monosodium urate crystals . Atefeh. . Rezaeifar. . Endorinology. Flow . May 2020 . Epidemiology and pathophysiology. Osteoporosis is a silent disorder characterized by . reduced bone strength predisposing to increased fracture risk .. Are They Clinically Useful?. Dr.Zahedi. fellow of endocrinology. bone turnover markers. BTM can be measured in serum, plasma and urine and their levels relate to the activity of osteoblasts (bone formation markers) and osteoclasts (bone . Bone markersof formationBone markersof resorption) cross-linkingcollagen (blood test)Procollagen type I Npropeptide () cross linkingcollagen (urine test) What is osteoporosis?Osteoporosis occurs when position statement . for the diagnosis and treatment of osteoporosis in . adults. Subhash C Kukreja, MD. University of Illinois . Chicago, IL, USA. Position Paper vs. Guidelines. A Position Paper . is a detailed policy report, drafted by members of a society, that explains or advocates a certain course of action. It’s commonly derived from research support studies. Hashemipour.s. MD . Endocrinologist . Qazvin university of medical science. Agenda . Definition. Potential Targets . Fracture. BMD. FRAX. Bone markers. Conclusion . What is treat to target strategy?. Normally, there exists a balance between bone formation & the bone resorption. In osteoporosis, . The rate of bone resorption exceeds the rate of bone formation rendering the bone weak and brittle with loss of bone mass resulting in the reduction of bone mineral density (BMD) due to the deficiency of Vitamin D & calcium..