PPT-Osteoporosis in thalassemia patients

Mohammadreza bordbar md Pediatric hematologist Hematology research center Shiraz university of medical sciences Osteoporosis overview overview Prevalence 10 million Americans with osteoporosis. Ellis J. Neufeld MD, PhD. Egan Family Foundation Chair in Transitional Medicine, Harvard Medical School. Associate Chief, Dana-Farber Boston Children’s Center for . Cancer and Blood Disorders . Chair, Medical Advisory Board, CAF. Ashutosh Lal, MD. Northern California Thalassemia Center. UCSF Benioff Children’s Hospital Oakland. Thalassemia Syndromes: . Many diagnoses. Oakland Data (n=203). What is the proportion of . non-transfusion-dependent thalassemia. What is Osteoporosis?. Bone is being broken down faster than new bone can be developed . Causes Bone to become weak and brittle. Happens in men and women but more often women after menopause. Occurs more often in caucasian or asian races. Shuktika. . Nandkekolyar. . MKSAP. A 72-year-old man is evaluated for a two-week history of low back pain. The patient has a history of alcoholism but stopped drinking alcohol 10 years ago. He also has stage 3 chronic kidney disease and a 50-pack-year smoking history. Current medications are hydrochlorothiazide, . C TAGALOG Ano ang Thalassemia?ng Thalassemia ay isang uri ng makakuha ng sapat na oxygen ang dugo, atTaon-taon ay dumarami ang bilang ngmga sanggol na ipinapanganak na mayAno ang mga palatandaan ngMay 1Osteoporosis meansporus bone or is also known as a bone disease that is a mesh-like structure inside the bone that becomes damaged The bone structure may be thin if either too much bone tissue has b MD; FRCP (London); . FRCPEdin. ; . FRCSEdin. T. halassemia. Hemoglobin molecule. : is the iron-containing oxygen-transport . metalloprotein. in the red blood cells of all vertebrates.. The normal . haemoglobin. Overview. Definitions. Epidemiology. Symptoms . Treatment. Effects of Exercise. Testing. Prescription. Conclusion. References. http://. www.beautyhealthwomen.com. /benefits-in-women. Video. http://. www.youtube.com/watch?v=rHyeZhcoZcQ. low bone . density. . It . occurs when the rate of bone . resorption. (. osteoclast cells. ) exceeds the rate of bone formation (osteoblast cells) resulting in fragile . bone tissue . subsequent fractures.. Silent carrier . α. -/. αα. . Normal complete blood count . α. -Thalassemia trait . αα. /- - (. α. -thalassemia 1) . or . α . -/. α . - (. α. -thalassemia 2) . Mild microcytic anemia . Hemoglobin H . Treatment. . and Prevention. Nahid Rianon, . M.D., . Dr.P.H. .. The University . of Texas . Health Science Center at Houston (UTHealth). Module . 3 . of 3. LEARNING OBJECTIVES:. At the end of this presentation, attendees will be able to. Atefeh. . Rezaeifar. . Endorinology. Flow . May 2020 . Epidemiology and pathophysiology. Osteoporosis is a silent disorder characterized by . reduced bone strength predisposing to increased fracture risk .. CABM FIBMS. OSTEOPOROSIS. Reduced bone density, which causes micro-architectural deterioration of bone tissue and leads to an increased risk of fracture (fragility fractures). Fragility Fractures. Defined as fractures result from falling from a standing height or less (occur spontaneously or following minimal trauma) . Normally, there exists a balance between bone formation & the bone resorption. In osteoporosis, . The rate of bone resorption exceeds the rate of bone formation rendering the bone weak and brittle with loss of bone mass resulting in the reduction of bone mineral density (BMD) due to the deficiency of Vitamin D & calcium..