PPT-Non-Transfusion-Dependent Thalassemia

Ashutosh Lal MD Northern California Thalassemia Center UCSF Benioff Childrens Hospital Oakland Thalassemia Syndromes Many diagnoses Oakland Data n203 What is the proportion of nontransfusiondependent thalassemia. Ellis J. Neufeld MD, PhD. Egan Family Foundation Chair in Transitional Medicine, Harvard Medical School. Associate Chief, Dana-Farber Boston Children’s Center for . Cancer and Blood Disorders . Chair, Medical Advisory Board, CAF. Based on the Patient Blood Management Guidelines. Be. . SINGLE . m. inded. Patient Blood Management Guidelines. www.blood.gov.au. . Single Unit. Transfusion Guideline. WHO . The stable, normovolaemic inpatient who . AswiththeAfricanelephantexperiments,multipleexperimentalsetupsareimplemented,includingcaller-independent(CI),rank-dependent(RD),age-dependent(AD),gender-dependent(GD)andcaller-dependent(CD).Evaluation An Evidence-Based . Approach. Haneen . Yasin. Abdella, MD. Hematology Oncology . Kidz. Medical Services. Miami Children’s Hospital. Objectives. Review the definite indications for . leukoreduced. “Blood transfusion is like marriage: it should not be entered upon lightly, unadvisedly or wantonly or more often than is absolutely necessary. .” . . –Robert Beal, past director of International Federation of Red Cross. Which is the Culprit for Worse Outcomes in Cardiac Surgery?. Damien J. LaPar MD, MSc, James M. Isbell MD, MSCI, Jeffrey B. Rich MD, . Alan M. . Speir. MD, Mohammed . Quader. , MD, Irving L. . Kron. MD, . Reduce Complications of . Prematurity. . A . Multi-site Quality Improvement Project. Sponsored . by the Indiana State Department of . Health. . Presenter: Sandra Hoesli, MD, MS. Objectives. Describe the Indiana Vermont Oxford Network Quality Collaborative (. Dr. Soheila . zareifar. Department of pediatric hematology/oncology. Shiraz university of medical sciences. Qeshm. 2018. Transfusion in Sickle Cell. In sickle cell disease transfusions improve blood flow by reducing the proportion of red cells capable of forming sickle hemoglobin polymer. . Thalassemia. Beta-thalassaemia is a global disease - most prevalent in South Asia, the Far East, the Middle East, and Mediterranean countries. . Distribution is attributed largely to natural selection of heterozygote carriers because of protection against falciparum malaria. . MD; FRCP (London); . FRCPEdin. ; . FRCSEdin. T. halassemia. Hemoglobin molecule. : is the iron-containing oxygen-transport . metalloprotein. in the red blood cells of all vertebrates.. The normal . haemoglobin. Thalassemia . is an inherited blood disorder in which the body makes an abnormal form of hemoglobin. Hemoglobin is the protein molecule in red blood cells that carries oxygen. Hemoglobin is formed by the combination of . Kakavoulis. . Nikolaos. Patras Ioannis. What is . Thalassaemia. ?. . Thalassaemia. is a group of inherited disorders of hemoglobin synthesis characterized by . reduced . or . absen. ce. . of one . Silent carrier . α. -/. αα. . Normal complete blood count . α. -Thalassemia trait . αα. /- - (. α. -thalassemia 1) . or . α . -/. α . - (. α. -thalassemia 2) . Mild microcytic anemia . Hemoglobin H . F.I.B.M.S (Int. Medicine) , F.I.B.M.S (Hematology). DEFINITION. Thalassemias . are inherited blood disorders characterized by defect . in the rate of synthesis of one . of the . globin chains.. Resultant imbalance of globin chain production may cause ineffective .