PPT-Thalassemia Thalassemia:

Thalassemia is an inherited blood disorder in which the body makes an abnormal form of hemoglobin Hemoglobin is the protein molecule in red blood cells that carries oxygen Hemoglobin is formed by the combination of . The Philadelphia Experience. Vanessa Nixon, The Children’s Hospital of Philadelphia. Linda . Slaven. , The Hospital of the University of Pennsylvania. Patients with thalassemia are living much longer . Ellis J. Neufeld MD, PhD. Egan Family Foundation Chair in Transitional Medicine, Harvard Medical School. Associate Chief, Dana-Farber Boston Children’s Center for . Cancer and Blood Disorders . Chair, Medical Advisory Board, CAF. Ashutosh Lal, MD. Northern California Thalassemia Center. UCSF Benioff Children’s Hospital Oakland. Thalassemia Syndromes: . Many diagnoses. Oakland Data (n=203). What is the proportion of . non-transfusion-dependent thalassemia. O+G Update 2014. Hospital . Sarikei. What is Anemia. Disorder by which the body is depleted of RBC to carry adequate oxygen to tissues. NICE Guidelines (for pregnant woman). Hb. level <10.5g/dl throughout pregnancy. b. d. g. a. a. Chromosome 16. Chromosome 11. 25%. 25%. a. a. b. d. g. 25%. 25%. 48%. 48%. 1.5%. 0.5%. 1.5%. 0.5%. Hemoglobin synthesis. a. a. a. a. a. a. b. g. d. b. d. g. HbA. HbF. HbA. 2. 98%. ~1%. Lecture . 7 . 1. White blood cells. Platelets. Red blood cells. Artery. Introduction . . 2. Physical Characteristics of . Blood. Heavier, thicker, and 3-4 . more . viscous than water. 38. o. C (100.4. Heidi Schultz. Oregon Health & Science University. 4/19/2010. Introduction. 83 year-old . Vietnamese . female.. Admitted . to the hospital on 2/17/10 . with chest pain.. Pt . was inpatient for a total of 22 . .. . Anemia…. What is Anemia?. A condition characterized by a decrease in RBCs mass, hemoglobin or RBCs count.. Adult male: . Hb. .  13 g/. dL. , or . Hct. .: 41%.. Adult Females: . Hb.  12 g/. C TAGALOG Ano ang Thalassemia?ng Thalassemia ay isang uri ng makakuha ng sapat na oxygen ang dugo, atTaon-taon ay dumarami ang bilang ngmga sanggol na ipinapanganak na mayAno ang mga palatandaan ngMay MD; FRCP (London); . FRCPEdin. ; . FRCSEdin. T. halassemia. Hemoglobin molecule. : is the iron-containing oxygen-transport . metalloprotein. in the red blood cells of all vertebrates.. The normal . haemoglobin. Kakavoulis. . Nikolaos. Patras Ioannis. What is . Thalassaemia. ?. . Thalassaemia. is a group of inherited disorders of hemoglobin synthesis characterized by . reduced . or . absen. ce. . of one . Silent carrier . α. -/. αα. . Normal complete blood count . α. -Thalassemia trait . αα. /- - (. α. -thalassemia 1) . or . α . -/. α . - (. α. -thalassemia 2) . Mild microcytic anemia . Hemoglobin H . THALASSEMIA SYNDROMES Info Sheet 1800ROSWELL (1  8007679355) | RoswellPark.org UNDERSTANDING HEMOGLOBIN This important protein in your red blood cells carries oxygen Newborn Screening ACT Sheet Beta Thalassemia Major(Hemoglobin F [Fetal] Only) Contact the family to inform them of the screening result.Evaluate infant, assess for splenomegaly, and do complete blood