PPT-Antigen Capture and  Presentation to T Lymphocytes

By Nader Alaridah MDPhD Features of Antigens Recognized by T Lymphocytes The antigen receptors of most T lymphocytes can see only peptide fragments of protein antigens and only when these peptides are presented by specialized molecules. T. h. e Specific Immune Response. OCR AS Biology – F212 – Module 2. Food & Health. Learning Objectives. Success Criteria. Understand the role of the specific immune system.. Understand the role of B and T Lymphocytes in fighting off pathogens.. T. h. e Specific Immune Response. OCR AS Biology – F212 – Module 2. Food & Health. Learning Objectives. Success Criteria. Understand the role of the specific immune system.. Understand the role of B and T Lymphocytes in fighting off pathogens.. 1. 33. Copyright © McGraw-Hill Global Education Holdings, LLC. Permission required for reproduction or display.. Immunity. Nonspecific . immune . response – . Ch. 33. Aka . nonspecific . resistance. Defense. . System. Third Line of . Defense. Immune . response . - response . to a . threat that targets specific antigens. 2 types of immunity:. Humoral. immunity = antibody-mediated . Provided by antibodies present in body fluids. Oral immunity and . immunopathological. processes in the mouth.  Immunity. Microorganisms are in the air we breathe and in/on the food we eat;. Thus our epithelial surfaces are continuously exposed to microorganisms;.  . Enzyme-Linked . ImmunoSorbant. Assay (ELISA). ELISA. ELISA - an acronym for . E. nzyme-. L. inked . I. mmuno. S. orbent. . A. ssay.. The ELISA assay is a widely used biochemical assay to detect in a sample the presence of and quantity of proteins, such as hormones and antibodies and bacteria or viruses.. Specific Defences. (e). Autoimmunity & Allergies. (. a. ) Immune Surveillance. (b) Clonal Selection Theory. KA2: Specific Defences. (d) Immunological Memory. (c) T and B Lymphocytes. By the end of this section you will be able to ….. . Public Health. Unit 4 – Immunology and Public Health. 1. The Immune System. 2. Infectious Diseases and immunity. Non-specific defences. Specific cellular defences. Transmission and control. Active Immunisation and Vaccination and the evasion of immune responses. GENESIS. 1.Lymphoblast. :15-20 micrometer. Large nucleus with rarely more than 2 distinct. nucleoli. Cytoplasm is blue as a narrow rim around the. large nucleus. Prolymphocyte. :. Prolymphocyte. :. Non-specific Immunity. Born with some immunity . Helps prevent disease. Helps slow disease progression. First line of defense. Non-specific, cont. .. Physical Barrier- . unbroken skin . Dr Rehma Dar. Assistant professor Pathology. Introduction to Immune System. Cell mediated vs Humoral Immunity. Hypersensitivity reactions. Autoimmune diseases. Transplant Rejection. Immunodeficiency states. Assis.Prof.Dr. . Suhad Faisal . Hatem. Innate immunity. . is considering first line of defense, an immediate response to a pathogen that does not confer lifelong protective immunity. It is includes :. Presenting Cells 99 attention has been paid to the APC require- ments for class II-restricted activation of T helper/inducer cells than class I- or class II- restricted cytotoxic T cells. Thus, most . molecules. , . their. . structure. , and . function. .. HLA . system. , 2nd . class. . molecules. , . their. . structure. , and . function. .. HLA . system. , . genetic. background. HLA . typing.