PPT-Antigen Capture and  Presentation to T Lymphocytes

By Nader Alaridah MDPhD Features of Antigens Recognized by T Lymphocytes The antigen receptors of most T lymphocytes can see only peptide fragments of protein antigens and only when these peptides are presented by specialized molecules. Steinman Kayo Inaba Shannon Turley Philippe Pierre and Ira Mellman ABSTRACT Antigen uptake processing and presenta tion by dendritic cells DCs have become amenable to cell biological approaches The critical events occur in DCs that are undergoing ma T. h. e Specific Immune Response. OCR AS Biology – F212 – Module 2. Food & Health. Learning Objectives. Success Criteria. Understand the role of the specific immune system.. Understand the role of B and T Lymphocytes in fighting off pathogens.. T. h. e Specific Immune Response. OCR AS Biology – F212 – Module 2. Food & Health. Learning Objectives. Success Criteria. Understand the role of the specific immune system.. Understand the role of B and T Lymphocytes in fighting off pathogens.. Defense. . System. Third Line of . Defense. Immune . response . - response . to a . threat that targets specific antigens. 2 types of immunity:. Humoral. immunity = antibody-mediated . Provided by antibodies present in body fluids. Specific Defences. (e). Autoimmunity & Allergies. (. a. ) Immune Surveillance. (b) Clonal Selection Theory. KA2: Specific Defences. (d) Immunological Memory. (c) T and B Lymphocytes. By the end of this section you will be able to ….. . Public Health. Unit 4 – Immunology and Public Health. 1. The Immune System. 2. Infectious Diseases and immunity. Non-specific defences. Specific cellular defences. Transmission and control. Active Immunisation and Vaccination and the evasion of immune responses. Cells of the Immune System. Physical & Chemical Barriers. Innate and Adaptive Immunity. Innate Defenses. Nonspecific physical and chemical barriers that contribute to resistance against infection. GENESIS. 1.Lymphoblast. :15-20 micrometer. Large nucleus with rarely more than 2 distinct. nucleoli. Cytoplasm is blue as a narrow rim around the. large nucleus. Prolymphocyte. :. Prolymphocyte. :. GENESIS. 1.Lymphoblast. :15-20 micrometer. Large nucleus with rarely more than 2 distinct. nucleoli. Cytoplasm is blue as a narrow rim around the. large nucleus. Prolymphocyte. :. Prolymphocyte. :. What are lymphocytes?. Lymphocytes. are a type of white blood cell (. leukocyte. ) found in the blood and lymph nodes. . Collectively, lymphocytes can recognize millions of different antigens, due to the large variation of lymphocytes produced. . Martin Liška. . Department . of. . Immunology. . and. . Allergology. . Faculty. . of. . Medicine. . and. . Faculty. . Hospital. in . Pilsen. Topics. :. Laboratory methods of assessment of . Enas. . Razzoqi. . B.D.S., M.Sc., . Ph.D. in . Periodontics. . Most important cytokines are. Cytokines are group of small soluble proteins or . glycoproteins. secreted by different cells in the body, usually in response to stimulation which act as messenger molecules transmitting signals to other cells and induced responses through binding to specific receptors to control and coordinate cellular behavior and function . Maysem. M. . Alwash. The Normal Immune Response . Immunity. :. . is defense against infectious pathogens,. .. The mechanisms of protection against infections fall into . two . broad categories: . . molecules. , . their. . structure. , and . function. .. HLA . system. , 2nd . class. . molecules. , . their. . structure. , and . function. .. HLA . system. , . genetic. background. HLA . typing.