PPT-Chapter 10 Radiation Carcinogenesis

Radiation effects Deterministic effects Stochastic effects Deterministic effects A deterministic effects has a threshold in dose The severity of the effect is dose related Radiation induced cataracts are an example of a deterministic effects. Most of them have the potential for both beneficial and harmful effects Even sunlight the most essential radiation of all can be harmful in excessive amounts Most public attention is given to the category of radiation known as ionizing radiation Thi in vitro. CLS 212. Microbicidal. . Microbicidal is the process or an agent that . kills. the microorganism. . The suffix . -. cidal. or . –. cide. means . ??( . See chapter 8 page 131. ). . Fact . vs. Fiction. Disclosures. No financial disclosures for myself or family. No off label uses will be discussed. One exception: I am a radiologist. 25+ years selling . xrays. for a living. Mortgages and college tuition still to pay. Carcinogenesis. Are there differences in the mechanisms of carcinogenesis associated with chemical, radiation, or dietary carcinogens?. What is Carcinogenesis?. Carcinogenesis is the production of cancer cells or the process of normal cells transforming into cancerous cells. . How is sunlight measured?. What types of radiation are more energetic than others?. What is the link between sun exposure and skin cancer?. How does Earth’s atmosphere naturally protect us from the Sun?. D. Sutton, L.T. Collins and J. Le Heron. of the IAEA publication (ISBN 978-92-0-131010-1):. Diagnostic Radiology Physics: . A Handbook for Teachers and Students. . . Objective:. . To familiarize students with the systems of radiation protection. Radiation Biology. Branch of biology concerned with the effects of ionizing radiation on living systems. Includes. Sequence of events occurring after the absorption of energy from ionizing radiation. A. Abdel . Baky. Associate Professor. Pharmacology and Toxicology. Carcinogenesis. Carcinogenesis is a multistep process at both the phenotypic and the genetic levels . that . end with the disease . J. WONDERGEM. of the IAEA publication (ISBN 978-92-0-131010-1):. Diagnostic Radiology Physics: . A Handbook for Teachers and Students. . Objective:. . To familiarize students with . the action of ionizing radiation. C. . Hindorf. of the IAEA publication (ISBN 92-0-107304-6):. Nuclear Medicine Physics:. A Handbook for Teachers and Students. . Objective: . To summarize the formalism of internal dosimetry and present its application in clinical practice. . LEC.5. Chemical carcinogenesis:. General principles of chemical carcinogens;. I. . Could be . natural or synthetic chemical. ..  . II. . Chemicals either . direct acting chemical. (. active without transformation in the body). J. C. Hourdakis and . R. . Nowotny. of the IAEA publication (ISBN 978-92-0-131010-1):. Diagnostic Radiology Physics: . A Handbook for Teachers and Students. . . Objective:. . To familiarize students with the instrumentation used for . Describe electromagnetic radiation.. Perform . calculations demonstrating the relationship among the speed of light, frequency, and wavelength.. Use . the inverse-square law to calculate radiation intensity at different distances.. Radioactivity. 2.Radiation interaction with Matter. . 3.Radiation Doses and hazard Assessment.  . Overview. Types of Radioactive Decay. Energetics. of Radioactive Decay. Characteristics of Radioactive Decay.