CHAPTER 20 The Cardiovascular System The Heart Principles of Anatomy and Physiology 14 th Edition The purpose of the chapter is to Learn about the components of the cardiovascular system Focus on the anatomy and physiology of the heart ID: 505032
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Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
CHAPTER 20The Cardiovascular System: The Heart
Principles of Anatomy and Physiology14th EditionSlide2
The purpose of the chapter is to:Learn about the components of the cardiovascular system
Focus on the anatomy and physiology of the heartLearn about the cardiac cycle
Discuss the various factors that influence heart rate and force of contractionIntroductionCopyright © 2014 John Wiley & Sons, Inc. All rights reserved.Slide3
The heart is located in the mediastinum
Location of the HeartCopyright © 2014 John Wiley & Sons, Inc. All rights reserved.Slide4
The heart is located in the mediastinum
Location of the HeartCopyright © 2014 John Wiley & Sons, Inc. All rights reserved.Slide5
The heart is enclosed and held in place by the pericardium
PericardiumCopyright © 2014 John Wiley & Sons, Inc. All rights reserved.Slide6
The pericardium consists of an outer fibrous pericardium and an inner serous pericardiumThe serous pericardium has 2 layers:
VisceralParietalThe visceral and parietal layers are separated by the serous cavity, a fluid-filled space
PericardiumCopyright © 2014 John Wiley & Sons, Inc. All rights reserved.Slide7
Anatomy Overview:
Cardiac Muscle
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.Cardiac MuscleYou must be connected to the Internet and in Slideshow Mode to run this animation.Slide8
The wall of the heart has 3 layers:Epicardium
MyocardiumEndocardium
Layers of the Heart WallCopyright © 2014 John Wiley & Sons, Inc. All rights reserved.Slide9
The chambers of the heart include two upper atria and two lower ventricles
Chambers of the HeartCopyright © 2014 John Wiley & Sons, Inc. All rights reserved.Slide10
The chambers of the heart include two upper atria and two lower ventricles
Chambers of the HeartCopyright © 2014 John Wiley & Sons, Inc. All rights reserved.Slide11
The right atrium receives blood from the superior and inferior vena cava and the coronary sinus
Right AtriumCopyright © 2014 John Wiley & Sons, Inc. All rights reserved.Slide12
The right ventricle receives blood from the right atrium and sends blood to the lungs
Right VentricleCopyright © 2014 John Wiley & Sons, Inc. All rights reserved.Slide13
The left atrium receives blood from the pulmonary veins
Left AtriumCopyright © 2014 John Wiley & Sons, Inc. All rights reserved.Slide14
The left ventricle receives
blood from the left atrium and sends blood all over the bodyThe wall of the left ventricle is much thicker than that of the right ventricleLeft Ventricle
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The fibrous skeleton of the heart:
Forms the foundation for which the heart valves attachServes as a point of insertion for cardiac muscle bundlesPrevents overstretching of the heart valvesActs as an electrical insulator
Fibrous SkeletonCopyright © 2014 John Wiley & Sons, Inc. All rights reserved.Slide16
The valves of the heart open and close in response to pressure changes as the heart contracts and relaxesRight and left atrioventricular valves
Prevent back flow from the ventricles into the atriaRight and left semilunar valvesPrevent back flow from the arteries into the ventricles
Heart Valves and Circulation of BloodCopyright © 2014 John Wiley & Sons, Inc. All rights reserved.Slide17
Heart Valves and Circulation of Blood
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When one set of valves is open, the other set is closed
Heart Valves and Circulation of BloodCopyright © 2014 John Wiley & Sons, Inc. All rights reserved.Slide19
Systemic and Pulmonary Circulations
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Coronary Circulation
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The Cardiovascular SystemAnatomy Overview:You must be connected to the Internet and in Slideshow Mode to run this animation.Slide21
Blood flow through coronary arteries delivers oxygenated blood and nutrients to the myocardium
Branches arise from the ascending aortaCoronary veins remove carbon dioxide and wastes from the myocardiumBranches converge at the coronary sinus
Coronary CirculationCopyright © 2014 John Wiley & Sons, Inc. All rights reserved.Slide22
Coronary Circulation
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Cardiac Muscle Tissue
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Cardiac Muscle Tissue
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Cardiac muscle cells are self-excitable, and therefore,
autorhythmicCardiac muscle cells repeatedly generate spontaneous action potentials that then trigger heart contractions
These cells form the conduction system, which is the route for propagating action potentials through the heart muscleThe Conduction SystemCopyright © 2014 John Wiley & Sons, Inc. All rights reserved.Slide26
The Conduction System
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The Conduction System
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Cardiac ConductionInteractions Animation:You must be connected to the Internet and in Slideshow Mode to run this animation.Slide28
The autorhythmic fibers in the SA node are the natural pacemaker of the heart because they initiate action potentials most oftenSignals from the nervous system and hormones (like epinephrine) can modify the heart rate and force of contraction but they do not set the fundamental rhythm
Influences on the Conduction System
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An action potential in a ventricular contractile fiber is characterized by a rapid depolarization, plateau, and repolarization
Action Potential in a Ventricular Fiber
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Cardiac muscle generates ATP via anaerobic cellular respiration and creatine
phosphate as backups to aerobic respirationATP Production in Cardiac Muscle
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An EKG is a recording of the electrical changes that accompany each heart beat
Electrocardiogram (EKG or ECG)Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.Slide32
Action Potential Propagation Through the Heart
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One cardiac cycle consists of the contraction (systole) and relaxation (diastole) of both atria, rapidly followed by the systole and diastole of both ventriclesElectrical events
Pressure changesHeart soundsVolume changesMechanical events
The Cardiac CycleCopyright © 2014 John Wiley & Sons, Inc. All rights reserved.Slide34
The Cardiac Cycle
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Cardiac CycleInteractions Animation:You must be connected to the Internet and in Slideshow Mode to run this animation.Slide35
Electrical Events
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Pressure Changes
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Heart Sounds
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Volume Changes
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Mechanical Events
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CO is the volume of blood ejected from the left or right ventricle into the aorta or pulmonary trunk each minuteStroke volume (SV) is the amount of blood pumped out of the ventricle in one beat
CO (mL/min) = SV (
mL/beat) x HR (beats/min)Cardiac Output (CO)Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.Slide42
Cardiac Output and the Factors That Influence It
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Cardiac OutputInteractions Animation:You must be connected to the Internet and in Slideshow Mode to run this animation.Slide43
3 factors regulate stroke volume:Preload
ContractilityAfterload
Regulation of Stroke VolumeCopyright © 2014 John Wiley & Sons, Inc. All rights reserved.Slide44
Several factors regulate heart rate:Autonomic nervous systemHormones
IonsAgeGenderPhysical fitnessTemperature
Regulation of Heart RateCopyright © 2014 John Wiley & Sons, Inc. All rights reserved.Slide45
Nervous System Regulation of the Heart
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Factors that Increase Cardiac Output
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Regular aerobic exercise can:Increase cardiac outputIncrease HDL
Decrease triglyceridesImprove lung functionDecrease blood pressureAssist in weight control
Exercise and the HeartCopyright © 2014 John Wiley & Sons, Inc. All rights reserved.Slide48
Help for Failing Hearts
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Development of the Heart
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Development of the Heart
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Coronary artery diseaseAtherosclerotic plaquesCongenital heart defects
ArrhythmiaCongestive heart failureDisorders: Homeostatic Imbalances
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End of Chapter 20Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.