PPT-Single amino acid substitution in the HIV-2 gp36 ectodomain

Dufrasne François Assistant PhD student AIDS Reference Laboratory Pôle de microbiologie médicale MBLGUniversité catholique de Louvain Belgium Madrid March 10th 2016 Human immunodeficiency . What are amino acids?. Amino acids are the building blocks of proteins.. In the body, they exist as zwitterions.. Zwitterions can behave as both an acid or a base.. Today we will:. Study . the acid-base properties of amino acids, . (Foundation Block). Dr. Ahmed Mujamammi. Dr. . Sumbul. . Fatma. Learning outcomes. What are the amino acids?. General structure.. Classification of amino acids.. Optical properties.. Amino acid configuration.. Formation of Aminoacyl tRNAs. Ribosome structure. Stages of Translation. Relationship between DNA, mRNA, and Protein Sequences. Translation and the Genetic Code. Amino acid structure. Four different groups are attached to the central carbon atom (. Subunits (building blocks) of peptides and proteins. Neurotransmitters. Metabolic intermediates. glutamate. γ. -. aminobutyric. acid. (GABA). Proteins are synthesized from 20 ‘standard’ . α. -amino acids. Their names have 3- and 1-letter abbreviations.. acids. Need to book. Molymods. (C,H,O & N) each group needs 16 single bonds, 4 double bonds, 4 Carbon, 2 Nitrogen, 4 oxygen, 10 hydrogen. Practical activity 21. ALSO! Need to give Mel 2 weeks notice on the chromatography . Debalina. . Mukhopadhyay. . . Containing carbon, hydrogen, nitrogen, oxygen. . Building blocks of protein. . Contain Amino group (NH2+) , carboxyl . group . (COO-) , Alkyl group (R ) / H . . alpha carbon contains the functional groups.. Stryer. Short Course, Chapter 31. Nitrogen fixation. Bacteria. Nitrogenase. Costly—16 ATP per N. 2. molecule. Assimilation into Amino Acids. In microorganisms/plants: assimilation of ammonia is key—synthesis of most amino acids. (Foundation Block). Learning outcomes. What are the amino acids?. General structure.. Classification of amino acids.. Optical properties.. Amino acid configuration.. Non-standard amino acids.. Derivatives of amino acids.. . are organic molecules that are the building block of . . proteins. .. -There is 20 . α. -amino acids commonly found in . proteins. . ( . they . have a carboxyl group and an amino group . . . (. N-. Catabolisim. of Amino Acid). *. transamination. *Deamination(oxidative or nonoxidative. . deamination. ). *Transdeamination. * NH. 3. transport . *formation of urea. .. . Transamination. *Transamination means transfer of amino group from α-amino acid to α-. backbone.  . atoms . (see aminoAcids1).  but a unique set of . side chain . atoms. It's the side chains that make the 20 amino acids different from each other. . 1. Use the three identical backbone pieces and three unique side chain pieces below to construct three amino acids in the space to the right.. unbranched. polymer chains composed of numerous small subunits or monomers is called amino acids .. There are 20 amino acids from which 18 have same structure.. DEFINATION. STRUCTURE. Amino acids have a central chiral carbon atom called alpha carbon. Groups attached to carbon atom are: . imino. acid.” . Figure 5: Comparison of the secondary amino group found in proline with the primary amino group found in other amino acids such as alanine.. 2. Proline: . Proline differs from other amino acids in that its side chain and amino N form a rigid, five -member red ring structure (Figure 5). Proline, then, has a secondary (rather than a primary) amino group. It is frequently referred to as an “. Download PDF Acid Reflux Solution Kit™ eBook by Barton - a comprehensive step-by-step system designed to treat acid reflux and heartburn issues naturally.