PPT-Chromosomal Abnormalities

Numerical Abnormalities Structural Abnormalities Numerical Abnormalities Gains and losses of whole chromosomes in the karyotype string are usually denoted by the use of either a plus or minus sign before the aberrant chromosome for example . 405 O Impacto das Altera Abnormalities in Chromosomal Number. Abnormalities in Chromosomal Structure:. Rearrangements. Fragile Sites. Define:. nondisjunction. polyploidy. aneupoidy. trisomy. monosomy. Abnormalities in chromosomal number. Infertility in the Mare. Introduction. Extrinsic Factors. Lack of Use. Sub-fertile Stallion. Poor management. Intrinsic Factors. Many, many, many. Age. Reported to have the most significant bearing on reproductive performance. Istanbul. . International. . Hospital. IVF . Center. Is . aneuploidy. . screening. an . efficient. . tool. in . embryo. . selection. ?. Best. . embryo. Symmetrical. . PNs. . with. . equal. Human chromosomes. Most cells in your body normally contain 46 chromosomes, organized into 23 pairs. In each of these 23 pairs, you've inherited one chromosome from your father and one from your mother. . blastocyst. is . partially embedded . in the endometrial . stroma. .. In the area over the . embryoblast. , the . trophoblast. has differentiated into two layers:. (. a) an inner layer of . mononucleated. Lecturer . Dr. Samah A. Jassam BSc MSc PhD . MRSB. Al-Mustansiriya University . Collage of Pharmacy. What is the secret behind the . transmission of hereditary characteristics from generation to . 12.1 Chromosomal Inheritance . 1. Genes are located on chromosomes; this is called the . chromosome theory of inheritance. .. 12.1 Chromosomal Inheritance. Chromosomes can be categorized as two types:. . sami. FICOG. CABCOG. Recurrent miscarriage. Definition :. ≥ 3 consecutive losses of clinically recognized pregnancies < 20 week gestation. Ectopic, molar, and biochemical pregnancies not included. What if it’s NOT just the number?. Gene Mutations. Damaged Chromosomes . –. sometimes a portion of a gene or chromosome is lost or damaged during meiosis. Gene mutation. – a mutation that affects the gene. Dr.Dianatpour. Medical Geneticist. Prenatal tests. Invasive. Karyotype. FISH. QF PCR. Array CGH. Noninvasive. NIPT. Karyotyping. Chromosome Preparation . Any tissue with living nucleated cells that undergo division can be used for studying human chromosomes. Most commonly circulating lymphocytes from . 1 1 . No. 3 . pp: 201 - 208 , March 201 3 Original a rticle The study of chromosomal abnormalities and heteromorphism in couples with 2 or 3 recurrent abortions in Shahid Beheshti H ospital of Ham Prepared by Rania Naoufal, M.D.. Learning Objectives. Chromosome structure. Chromatin. Chromatin exists in several alternative configurations, depending on what that particular stretch of DNA is doing. Asmaa A. Almukhtar .PHD . Lecturer . Medical Genetic Department. ICCMGR. 2023. Introduction to Chromosomal Analysis. Reading &Writing a Chromosomal Analysis Report. How to write the chromosomal analysis report?.