PPT-DRUG TOXICITY

Dr Naila Abrar LEARNING OBJECTIVES By the end of this session you should be able to define drug toxicity know the types of toxicity comprehend the reasons that may lead to toxicity of . Alex Battistini. Pharmacology of digoxin. Clinical Uses. Overview. Introduction. Toxicity and management. 1. 2. 3. 4. Digitalis: Cardiac glycoside that occurs naturally in plants. Its medical use dates back from the 18. Lecture 1: Principles of Toxicology. Principles of Toxicity. Defining toxicology. History of toxicology. Dose response. Evaluating safety. Toxicology. Toxicology is the study of adverse effects of . chemicals . and . risks. for . human. . health. of . nanomaterials. Anne Braun. Head of the . Experimental. . Toxicology. Unit. INERIS Institut National de l’Environnement industriel et des . RISques. (National Institute for . Chemical . Mixtures. Thomas Backhaus. University of Gothenburg. thomas.backhaus@dpes.gu.se. Chemical Mixtures. Mixtures of toxic chemicals. Aquatic Ecosystems. Ecotoxicology. Focus. PREDICT. BEAM. ACE. http://www.ewg.org/skindeep. /. . Christine . Girtain. Toms River HS South. NJESTA Board Member. http://www.njesta.org/. . cgirtain@trschools.com. . Myth – . FDA promptly recalls any product that injures people. Dr Shaheen. Delivered By . Dr Naser . Drug interactions- objectives. Discuss Pharmacokinetic interactions. List . Pharmacodynamic. interactions. Comment . on common Drug- Food interactions. Drug interactions. Mohsen George, MD. Vice President, Health Insurance Organization . First Undersecretary MOHP - Egypt. Second Regional Health Technology Assessment Policy Forum. 17 – 18 September 2018, Dubai. Cancer Treatment is Evolving very Rapidly. ng closure and severe pain and this is However, there have been occasions where e, with the eyes closed and extremely recovery starts, it is a rapid processresult in a significant recovery 4. The HO OJ Bolognini V Koch-Weser J Harmatz JS Pharmacokinetic approach to the clinical use of lidocaine intravenously JAMA 1976 2362737 12 Pieroni RE Fisher JG Use of cholestyramine resin in digitoxin toxici Under supervision : . Dr.Mohammad. . Althnaybat. . Presented by Mohammad . Sanwar. binds to hemoglobin, myoglobin, mitochondrial cytochrome oxidase . . decreased oxygen delivery to the tissues.. Jesse Conterato, . BA&Sc. .. RSNA 2016. Hydrogel Spacers: MRI Comparison. Axial. View. Sagittal. View. Pinkawa. et al. WJCO 2015. Without Spacer. With Spacer. Absorbable polyethylene glycol hydrogel spacers are injected into the . Alexia Iasonos, . Irina Ostrovnaya. Department of Biostatistics. Memorial Sloan Kettering Cancer Center. . CRM Workshop, October 2009. Motivation. Retrospective analysis of completed Phase I studies in order to recommend, possibly, a new MTD . Brennan Geiger. 1. , Benjamin Riordan. 1,2. ,  Daniel Winter. 1. , Jacques Raubenheimer. 1. , Paul Haber. 1.  , Andrew Dawson. 1. 1  . Edith Collins Centre (Translational Research in Alcohol, Drugs and Toxicology), Sydney Local Health District. Acronyms used in preclinical . development. Beginners. Brief recall about clinical trials. The Funnel. Road map. Example of drug development: . . Chemical level. . Pharmaceutical level. . Preclinical pharmacology.