PPT-The Distribution of Chromosomal Aberrations in Human Cells

A L Ponomarev 1 3 K George 13 F A Cucinotta 3 1 USRA 3600 Bay Area Blvd Houston TX 77058 2 Wyle 1290 Hercules Drive Houston 77058 3 NASA JSC Mail Code SK 2101 NASA Parkway Houston TX 77058. Instituto de Oftalmología, Fundación Conde de Valenciana, I.A.P. .. Authors: Oscar Mac. ías Manuel, MD. Alejandro Navas Perez, MD. Coauthors: Enrique Graue, MD. Tito Ramírez Luquín, MD. Authors have no financial interest. The Cartesian ellipsoid . produces a stigmatic image of only one object point. Normal eye and most of optical systems are not free from aberration. . . Reference sphere:. . a circular arc centered on the image point with a radius equal to the image distance. Abnormalities in Chromosomal Number. Abnormalities in Chromosomal Structure:. Rearrangements. Fragile Sites. Define:. nondisjunction. polyploidy. aneupoidy. trisomy. monosomy. Abnormalities in chromosomal number. Cytogenetics. CDC’s 2003 Science Ambassador Program. Chromosomal Karyotypes. Overview. I. Chromosomes. A. Definition. B. Structure. C. Identification. II. Karyotypes. A. Definition. Cytogenetics. CDC’s 2003 Science Ambassador Program. Overview. I. Chromosomal Variations. A. Polyploidy. B. Aneuploidy. II. Syndromes resulting from Aneuploidy. A. Trisomy 13. B. Trisomy 18. C. Down Syndrome. Yuvaraja’s College. University of Mysore, Mysore. 11 September 2020. 1. www.hbmahesh.weebly.com. Chromosomes . have definite . structure and organization, which is normally constant from one cell division to next. . 12.1 Chromosomal Inheritance . 1. Genes are located on chromosomes; this is called the . chromosome theory of inheritance. .. 12.1 Chromosomal Inheritance. Chromosomes can be categorized as two types:. ! . Asmaa A. Almukhtar .PHD . Lecturer . Medical Genetic Department. ICCMGR. 2021. How to read karyotype?. Need to know chromosomal structure and composition. What is the karyotype?(photograph). What is the karyotyping?(process). Prokaryotic cell. Plasmid (ring of DNA. ). 50 x Smaller 0.2-2μm. 50 x Bigger 10-100μm. And small rings of DNA called plasmids. Inside a nucleus. Main differences. Prokaryotes:. SIZE – 50 x smaller than eukaryotes. R. Selvi a , Govind Raghav Saranya a , Jyotsna Murthy b , Andrea Mary F a , Solomon F. D. Paul a CORRESPONDING AUTHOR : Ms. R. SELVI Lecturer, Department of Human Genetics, Sri Ramachandra Universit 1 1 . No. 3 . pp: 201 - 208 , March 201 3 Original a rticle The study of chromosomal abnormalities and heteromorphism in couples with 2 or 3 recurrent abortions in Shahid Beheshti H ospital of Ham : 2967-2974(2004) Panani et al: Chromosomal Aberrations in Primary Bladder Cancer 2969 Figure 1.A,B,C. Partial karyotypes showing add(11p), add(14q) and add(19q) respectively ( different cases). Karyo Prepared by Rania Naoufal, M.D.. Learning Objectives. Chromosome structure. Chromatin. Chromatin exists in several alternative configurations, depending on what that particular stretch of DNA is doing. Asmaa A. Almukhtar .PHD . Lecturer . Medical Genetic Department. ICCMGR. 2023. Introduction to Chromosomal Analysis. Reading &Writing a Chromosomal Analysis Report. How to write the chromosomal analysis report?.