PPT-Warfarin Sodium (Anticoagulant)

Therapy Training 03102015 Objectives 1 What is an anticoagulant 2 Why is anticoagulant therapy necessary 3 What is a PTINR 4 Who can give Warfarin sodium Heart Pumps blood through the body. R2 Patcharee Seesongsom. R2 . Sirada. . Phojai. Advisor AJ . T. a. chawan. . J. iratiwanon. Scope. Overview. Introduction of NOACs. Rivaroxaban. ( . Xarelto. ). Dabigatran. ( . Pradaxa. ). Advantages of NOACs. No INR monitoring required. No bridging required . Easier to manage around surgical procedures. Convenient for rural patients or those with other barriers to . clinic . visits. Fewer. Indication and Target INRAtrial Fibrillation / Atrial Flutter INR 23 Goal 25Stroke INR 23 Goal 25Mechanical ValveAortic Position INR 23 Goal 2Aortic PositionMitral Position INR 2535 Goal 3 OtherPos Lanae Fox, . PharmD. , BCPS. I have no financial disclosures to report. Objectives. Understand the relative benefits and limitations of oral anticoagulant options. Recognize strategies for optimal use of oral anticoagulants and minimize risk of bleeding with these agents. Dr. . Versha. Prasad. Anticoagulants Used In the Hematology Laboratory. Anticoagulants are defined as substances which prevent blood clotting / coagulation, and allow separation of the blood into cellular and liquid (plasma) components. Generally plasma contains coagulation factors. . Thrombotic . or thromboembolic disease is common and has severe consequences, including myocardial infarction, stroke, deep vein thrombosis and pulmonary embolism. Hemostasis. . is a finely regulated dynamic process of maintaining fluidity of the blood, repairing vascular injury, and limiting blood loss while avoiding vessel occlusion (thrombosis) and inadequate perfusion of vital organs.. & safe anticoagulant prescribing. July 2020. Dr Clare Brown . Slides by Dr . Julia . Anderson. Department of Haematology. Royal Infirmary of Edinburgh. Plan for today. Where to locate the antithrombotic guidelines and protocols. :. are additives that inhibit clotting of blood and/or plasma. They act either by binding calcium ions or by inhibiting thrombin activity. . Platelets and coagulation factors are activated when blood vessels are punctured, and their activation continues in sample containers that do not contain anticoagulant, leads to clot formation which interfere with many analytical tests.. Patients with anticoagulant. (n=37). R-CHOP,. . n (%). 156 (51.0). 14 (37.8). R-CEOP, . n (%). 68 (22.2). 7 (18.9). R-CHOEP, . n (%). 47 (15.3). 2 (5.4). R-CVOP, . n (%). 11 (3.6). 10 (27.0). R-mini-CHOP, . existing clots from growing larger. Although anticoagulants are sometimes called blood thinners , they do not actually thin the blood. The job of anticoagulants is to promote the smooth flow of bloo 1 COUMADIN Tablets for oralLactose, starch and magnesium stearate 1 mg: D&C Red No. 6 Barium Lake 2 mg: FD&C Blue No. 2 Aluminum Lake and FD&C Red No. 40 Aluminum Lake 2-1/2 mg: D&C Yellow No. 10 . Classify drugs acting as anticoagulants. . Elaborate on their mechanism of action, correlating that with methods of monitoring. . Contrast the limitations & benefits of injectable anticoagulants in clinical settings. Oliguria. Hypoxia. Tachycardia. Cover Shifts part 3 - Dr Carol Chong. What meds are in your armamentarium?. Constipation. 1/7 of constipation. Coloxyl. and . senna. 2 tablets . b.d. +. Lactulose. 20mls o . Josh Smith. Overview. Adverse Drug Reactions. Toxicities. Adverse Drug Reaction. Type A Adverse drug reaction. Dose dependent . Preventable. Type B ADR. Idiosyncratic. Multifactorial. Underlying disease (kidney or liver dysfunction).