PPT-Arterial blood gases and acid-base balance

Professor Stephen Semple ssempleimperialacuk Daltons Law of Partial Gas Pressures In a gas mixture the pressure exerted by each gas is independent of the pressures of the other gases The Partial pressure of a gas is the concentration of the gas times the Barometric Pressure eg Po. Objectives:. . TO UNDERSTAND THE NATURE OF OCCLUSIVE ARTERIAL DISEASE AND ITS ASSOCIATED SYMPYOMS AND SIGNS. TO ABLE TO ASSESS ACUTE AND CHRONIC ARTERIAL INSUFFICIENCY AND KNOW TREATMENT OPTIONS.. Carrie George, MD. Pediatric Critical Care Medicine. Adapted from Dr. Lara Nelson. Blood Gas Analysis. Acid-base status . Oxygenation. Anatomy of a Blood Gas. pH/pCO. 2. /pO. 2. /HCO. 3. Base: metabolic. Titration. Acid–Base Titration. The concentration of a weak acid or a weak base in water is difficult – if not impossible – to measure directly.. But we can calculate the concentration from the results of titration.. MLAB 2401: Clinical Chemistry. Keri Brophy-Martinez. Terms. Acid. Any substance that can yield a hydrogen ion (H. +. ) or hydronium ion when dissolved in water. Release of proton or H. +. Base. Substance that can yield hydroxyl ions (OH. Acids are produced continuously during normal metabolism. . (provide H+ to blood). . H. +. ion concentration of blood varies between narrow limits. . pH of the extracellular fluid = 7.35 – 7.45. Learning Objectives. Describe . what is meant by acids, bases and . buffers. List . normal pH of the body fluids. . Describe . the processes involved in maintenance of normal blood pH. .. Describe . various types of acidosis and alkalosis. OR. Regulation of Blood . pH. Dr. Anissa Atif Mirza. Synopsis. Introduction. Sources of Acids and Bases in body. What is Acid Base Balance?. Mechanisms Regulating Blood pH.. Significance of Maintaining Acid Base Balance. For cells to function optimally, . a steady balance . between the acids and the bases . is necessary.. Acid-base balance represents homeostasis of hydrogen (H+) ion . concentration in . body fluids. . Outlines. Introduction . Components of ABG . Oxygenation . Ventilation . and Acid-Base . Status . PaO2, PH, PaCO2, HCO3, buffer system, base excess o . rbase. deficit and compensation. . Signs and Symptoms of . Schedule. Intro. Why the pH value of body fluids must be “defended”. Defining pH. Logarithms . (see appendix). Acidosis and alkalosis. Biological Buffers and the Henderson-. Hasselbalch. equation. Many critical illnesses can disturb acid-base balance.. Acid-base disturbances may indicate an underlying disease or organ damage.. Accurate interpretation of acid-base disturbances requires the following:. This lecture presents the basic concepts of pharmaceutical inorganic chemistry with emphasis on the description, mechanisms and uses of various pharmaceutical products which are clinically used to correct various body disorders. The major topics to be covered are acids and bases, intra and extra cellular electrolytes, the gastrointestinal agents and topical agents frequently employed in the conversion of drugs to chemical forms convenient to their product formulations.. Download PDF Acid Reflux Solution Kit™ eBook by Barton - a comprehensive step-by-step system designed to treat acid reflux and heartburn issues naturally. Acid. is defined as a substance which when dissolved in water gives hydrogen ions. (H +) . Examples.. Base is defined as a substance which when dissolved in water gives hydroxyl ions. (OH-) . Examples..