PPT-ACID BASE BALANCE OR Homeostasis of Blood pH

OR Regulation of Blood pH Dr Anissa Atif Mirza Synopsis Introduction Sources of Acids and Bases in body What is Acid Base Balance Mechanisms Regulating Blood pH Significance of Maintaining Acid Base Balance. Janis Rusin APN, MSN, CPNP-AC. Pediatric Nurse Practitioner. Lurie Children’s Transport Team. Objectives. Discuss the mechanisms for maintaining normal acid-base balance. Define respiratory and metabolic acidosis and alkalosis. MLAB 2401: Clinical Chemistry. Keri Brophy-Martinez. Terms. Acid. Any substance that can yield a hydrogen ion (H. +. ) or hydronium ion when dissolved in water. Release of proton or H. +. Base. Substance that can yield hydroxyl ions (OH. Fluid, Electrolyte, and Acid-Base Balance. Body Water Content. Infants: 73% or more water (low body fat, low bone mass). Adult males: ~60% water. Adult females: ~50% water (higher fat content, less skeletal muscle mass). Fluid, Electrolyte, and Acid-Base Balance. 1. Body Water Content. Infants have low body fat, low bone mass, and are 73% or more water. Total water content declines throughout life. Healthy males are about 60% water; healthy females are around 50%. Acid-base balance . (H. . production = loss). Normal plasma pH: 7.35–7.45. H. . gains: many metabolic activities produce acids. CO. 2. (to carbonic acid) from aerobic respiration. Lactic acid from glycolysis. Acids are produced continuously during normal metabolism. . (provide H+ to blood). . H. +. ion concentration of blood varies between narrow limits. . pH of the extracellular fluid = 7.35 – 7.45. M. . Gardner. Copyright2/4/2013. ACID /BASE BALANCE. In order to meet homeostasis, the body fluids must maintain a stable chemical balance of hydrogen ions in body fluids.. This is done by regulating their acidity /alkalinity. . Learning Objectives. Describe . what is meant by acids, bases and . buffers. List . normal pH of the body fluids. . Describe . the processes involved in maintenance of normal blood pH. .. Describe . various types of acidosis and alkalosis. For cells to function optimally, . a steady balance . between the acids and the bases . is necessary.. Acid-base balance represents homeostasis of hydrogen (H+) ion . concentration in . body fluids. . Schedule. Intro. Why the pH value of body fluids must be “defended”. Defining pH. Logarithms . (see appendix). Acidosis and alkalosis. Biological Buffers and the Henderson-. Hasselbalch. equation. . hassan. objectives. 1. Describe the physiology involved in the acid/base balance of the body.. 2. Compare the roles of PaO2, pH, PaCO2 and Bicarbonate in maintaining acid/base balance.. 3. Review causes and treatments of Respiratory Acidosis, Respiratory Alkalosis, . Many critical illnesses can disturb acid-base balance.. Acid-base disturbances may indicate an underlying disease or organ damage.. Accurate interpretation of acid-base disturbances requires the following:. Gas Analysis. (Part . I). april. 2018. Clinical Pathology fellowship program. Definitions. Term. Definition. Acid (HA). A substance that can yield a hydrogen\ hydronium ion when dissolved in water (gives off a H. Acid-base balance.  . * Acids are electrolytes that release hydrogen ions (H+) when they are dissolved in water.. * Bases are electrolytes are release hydroxide ions (OH-) when they are dissolved in water..