PPT-Simon Thornley Meta-analysis: pooling study results

Objective Understand the philosophy of metaanalysis and its contribution to epidemiology and science Understand the limitations of metaanalysis Introduction Systematic quantitative integration of results . Stata. programs for network meta-analysis. UK . Stata. users’ Group. London, 13. th. September 2013. Ian . White. MRC Biostatistics Unit, Cambridge, UK. Plan. Ordinary (. pairwise. ) meta-analysis. Meta-analysis: pooling study results. Objective. Understand the philosophy of meta-analysis and its contribution to epidemiology and science.. Understand the limitations of meta-analysis. Introduction. and SCD Meta-Analyses. William R. Shadish. University of California, Merced. Borrowing liberally from coauthored work with Larry Hedges, David . Rindskopf. , James . Pustejovsky. , . Kristynn. Sullivan, Jonathan . de chimiothérapie dans les cancers des . VADS: actualisation. Jean-Pierre . Pignon. , . Pierre . Blanchard, . Anne . Lee, . Laureen. . Majed. , Sophie . Marguet. , . Claire . Petit, Cécile . Landais. Sven . Kepes & Michael A. McDaniel. April 29, 2017. Outline. Meta-analysis . and cumulative knowledge . Sensitivity analysis. Sensitivity analysis: . Outliers. Sensitivity analysis: Publication . EPI 811 Individual Presentation. Chapter 10 of . Szklo. and Nieto’s . Epidemiology: Beyond the Basics. Anton Frattaroli. Sensitivity Analysis. Generally, an assessment of how systematic or random errors affect an effect estimates’ representativeness of the actual effect (the validity of the effect estimate).. UK . Stata. users’ Group. London, 13. th. September 2013. Ian . White. MRC Biostatistics Unit, Cambridge, UK. Plan. Ordinary (. pairwise. ) meta-analysis. Multiple treatments: indirect comparisons, consistency, inconsistency. Jaswin Sawhney. Maine Medical Center. Portland, Maine. Introduction to Meta-Analysis. What is a systematic review? . A systematic review is a research methodology that tries to identify, select, appraise, and synthesize all research evidence relevant to a specific research question . Hardy-Weinberg equilibrium. Meta-analysis. SNP Imputation. Review what we have learned about the genetics of common disease from GWAS. Where do we go from here? What do we go with GWAS results.. functional characterization of GWAS loci. Outline. Introduction. Two review papers. Quality control (. MetaQC. ). Meta-analysis for detecting differentially expressed genes (. MetaDE. ). Meta-analysis for detecting pathways (. MetaPath. ). 1. Introduction. 1 - analysis Tony Hak, Henk van Rhee , & Robert Suurmond Version 1.0, March 2016 Version 1.3, Updated June 2018 Version 1 .4, Updated July 2018 Meta - analysis is a systematic method for synthesizing Inês Barroso. Joint Head of Human Genetics. Metabolic Disease Group Leader. Wellcome. Trust Sanger Institute. 1. Objectives. Why perform meta-analysis?. How? . What are the issues to consider?. What can you gain?. Presented by Christine R. Wells, Ph.D.. Statistical Methods and Data Analytics. UCLA Office of Advanced Research Computing. What to expect from this workshop. Definition of systematic review and meta-analysis. Simon Wandel, Expert Stat Methodologist Novartis Pharma AG, Basel. PSI conference 2017. Co-authors. Qing Liu, Novartis. Steven . Green, Novartis. Beat . Neuenschwander, Novartis. Acknowledgements. Satrajit Roychoudhury, Novartis.