PPT-THALASSAEMIA AND REALITIES

Dr Androulla Eleftheriou Executive Director Thalassaemia International Federation Brussels 26 September 2019 TABLE OF CONTENTS Haemoglobinopathies A global public health issue Focus on . 1 Regular blood transfusions are needed to . maintainthe. . haemoglobin. over 10 g/. dL. at all times. . This usually requires 2-3 units every 4-6 weeks. Fresh blood. , filtered to . remove white . Anaemia. . ?. Anaemia . is defined as reduction in circulating.  . haemoglobin mass below. . the. critical. . level.. The normal . haemoglobin . (Hb) . is . 12-14. . gm%.. . WHO has . accepted . Thalassemia. Beta-thalassaemia is a global disease - most prevalent in South Asia, the Far East, the Middle East, and Mediterranean countries. . Distribution is attributed largely to natural selection of heterozygote carriers because of protection against falciparum malaria. . MD; FRCP (London); . FRCPEdin. ; . FRCSEdin. T. halassemia. Hemoglobin molecule. : is the iron-containing oxygen-transport . metalloprotein. in the red blood cells of all vertebrates.. The normal . haemoglobin. Kakavoulis. . Nikolaos. Patras Ioannis. What is . Thalassaemia. ?. . Thalassaemia. is a group of inherited disorders of hemoglobin synthesis characterized by . reduced . or . absen. ce. . of one . مؤيد . علو. ش. Lec. . 2. Thalassaemias. Objectives:. 1-Define thalassemia and its main types(. β. and . α. ). 2- Know the . genetic . lesions of each of . β . and . α. thalassemia. 3-Know the difference between thalassemia minor and major.. T. halassaemia. , . Diagnosis . & . Management. Dr . Md. . Saqif. . Shahriar. MBBS ,MD(Cardiology). Interventional . cardiologist,NICVD,Dhaka. .. The cardiovascular complications . of . thalassaemia. MB;BS(Ilorin), FWACP(. Paed. ). Outline. Intro /def. Normal haemoglobin structure / function. Classification of haemoglobinopathies . Structural Hb Variants. Thalassaemias. Epidemiology. Clinical features. 1 1 DOI: 10.7860/JCDR/2019/39865.12646 Dentistry Section Radiological Features of Thalassaemia-An Update Review Article Original Article Miscellaneous Postgraduate Education Letter to Editor Short Co مؤيد علوش. Introduction. THE HAEMOGLOBIN MOLECULE. Human . haemoglobin. is formed from two pairs of . globin chains . each with a . haem. . group attached.. Seven . different globin . chains are . Dr . Tasneem. . Ara. . Associate Professor. Department of Hematology & Bone marrow transplantation unit . DMCH . 11/11/18. This presentation includes. Introduction. Social awareness . Screening for . Publications Launch Webinar. Thursday 28. th. January 2021. Welcome to NHS Sickle Cell and Thalassaemia Screening Programme’s Live Webinar. Thursday 28. th. January 2021. Chair: Professor Dame Elizabeth N . . Assist. Prof. . Dr.Maysem. . Mouayad. . Alwash. . Note:. The . thalassaemias. are classified into . α. -, . β. -, . δβ. -, . γδβ. -, . δ. -, . γ. - and . εγδβ. -thalassaemias, according to the type of globin chain(s). of . haemoglobin. Ass. . Prof. . . Abeer. . Anwer. Ahmed. Normal adult blood contains three types of . haemoglobin. . Hb. . A . . Hb. . F . . Hb. . A2. Structure .