PPT-Eukaryotic Chromosome Organization

Lecture II Dr Steven J Pittler VH 375B Office 46744 Cell 6129720 Suggested Reading Lewis 2nd Edition Chapter on Chromosomes Chromosomes Structures that consists primarily of DNA and proteins that are duplicated and transmitted during mitosis or meiosis. The Big Epigenetic Event. Males – 46,XY. Females – 46,XX. Compensate for gene dosage, all mammals inactivate extra X chromosome. Discovered by Mary Lyon. Lyon, M.F., 1961. Gene action in X-chromosome of the mouse (. TSW – Recognize that the presence of a nucleus determines whether a cell is prokaryotic or eukaryotic. 6.12B. Cells. There are two . basic types . of cells. Prokaryotes. or prokaryotic cells . Eukaryotes. Copyright © 2002 Pearson Education, Inc., publishing as Benjamin Cummings. Eukaryotic Cell. 3. Eu. = True. Karyon. = Nucleus. B- The Eukaryotic Cell. Animal Cell. Plant Cell. Compare Animal and Plant cell. September. . 27. th. , . 2016. Bellwork. What number of chromosome determines the gender?. Chromosome . p.48. Essential Question: How can I make and illustrate a chromosome and it’s gene . locations?. Multicellular. . Organisms. Overview. Review of key structural and genetic features of eukaryotic cells.. Remind yourself of these by your own reading. .. The origin of cells with eukaryotic organization, some 2.5 . SUBMITTED BY:. ALABADO, SHEENA ANN C.. LUISTRO, JANELLE. What is a chromosome?. A chromosome is…. A very long DNA molecule and associated proteins that carries portions of the hereditary information of an organism.. Chromatin – the less tightly coiled DNA-protein complex. Centromere – the region of the chromosome that holds the two sister chromatids together during mitosis.. SEX CHROMOSOMES & AUTOSOMES. Sex chromosomes are chromosomes that determine the sex of an organism, and they may also carry genes for other characteristics. . Aneuploidy. :. Variation of a certain chromosome with in the set.. Hyperploidy. : gain of chromosome. Trisomy 2n+1. Double trisomy 2n+1+1. Tetrasomy. 2n+2. Hypoploid. y. : loss of chromosome. Monosomy 2n-1. Chromosomes. The . term chromosome was coined by W. . Waldeyer. in 1888. .. Their . structures . varies in . different organisms . like . they are circular in . bacteria. . but . linear in eukaryotic organisms, however there number remains constant for a species.. Eukaryotic translation. Eukaryotic mRNAs are characterized by two post-transcriptional modifications: the 5-terminal 7methyl-GTP cap and the 3-terminal poly(A) tail .. The 7methyl-GTP cap is essential for mRNA binding by eukaryotic . : is the general morphology of the somatic chromosome. Generally, . karyotypes. represent by arranging in the descending order of size keeping their . centromeres. in a straight line.. Idiotype. : the . chemoselectivity. at interfaces.. . Dmitry . Eremin. Fundamentals of protein ionization. Used DMSO solution to assist protein. ionization and improve signal-to-noise ratio. Eremin, D.B. and . Fokin. FLOW CYTOMETRY AppCATn nOTE minimal debris formation and large numbers of indiidual chromosomes for a well-resoled flow karyotype, protocols hae made use of stabilizing agents such as dialent c Euploid. Have the . normal. chromosome number. Polyploid. A cell with . extra sets. of chromosomes. Ex: triploid (3n). Aneuploid. Cells missing a single chromosome or having an extra chromosome. Alterations in Chromosome Number.