PPT-ANTIHISTAMINES

Histamine To understand antihistamines you have to slightly understand what it is blocking Histamine There are 4 different histamine receptors H 1 H 4 We will be focusing on H1 H1 receptors are located in the lower respiratory tract and skin. CLARITIN launched as an OTC in 1990 and by the mid 90s was market leader Editor s note see CASSIES I In early 1995 Reactine took the OTC route It was the 1 prescription drug and it invested massively in launch advertising outspending CLARITIN 21 By 16 Supplement 1312 2006 Esmon Publicidad Comparative pharmacology of the H antihistamines First Chlorpheniramine 28 08 3 Diphenhydramine 17 10 2 Doxepin 2 na Hydroxyzine 21 04 2 Acrivastine 14 04 1 Ketotifen 36 16 na Cetirizine 10 05 1 Lorat . By: Jean Collado . Before Learning About Antihistamines . We must learn about histamine. . . Histamine is an organic nitrogen compound involved with our immune . system. It was . discovered in 1910 by Henry Dale and Patrick Laidlaw. Copyright Regulations 1969. WARNING. This material has been copied and communicated to. . you by or on behalf of the University of Sydney. . pursuant to Part VB of the Copyright Act 1968. . (The Act).. Dr K Outhoff. Contents. Allergic Rhinitis. Nasal furunculosis. Epistaxis. Local anaesthetic drugs. Rhinosinusitis. Viral. Bacterial. Fungal. Iatrogenic conditions. A. Nasal Obstruction. Viral URTI . Allergy is a reaction with inflammatory cell infiltration inthe target organ which allergen has been found to causethe target organ which allergen has been found to causeAllergens cause an immunoglobu with doctor or pharmacist Antihistamines: Non-prescription medications and supplements: MEDICATIONS THAT SHOULD BE AVOIDEDMEDICATIONS TO BE AVOIDED OR USED WITH CAUTION IN PARKINSON’S DISEASE Not . What is Rhinitis?. The nasal passages are lined with a membrane that produces mucus. Mucus is one of the body's defense systems:. Thin clear liquid, traps small particles and bacteria . The trapped bacteria usually remain harmless in healthy individuals. Cardiovascular & Medicine Symposium . Thomas A. Lupoli, D.O.. Board Certified Allergist/Immunologist. Disclaimers and Disclosures. Aerocrine. Speakers Bureau. Executive Board Member-- Florida Allergy, Asthma & Immunology Society . Histamine. Endogenous compound. Found in specialized cells. Important role in:. Allergic reaction. Regulation of . gastric acid secretion. Histamine use limited to diagnostic procedures. Histamine. Distribution. RESPIRATORY SYSTEM . 1. The main function of coughing is airway clearance. . Excess . secretions and foreign bodies are cleared from the lungs by a combination of coughing and the . mucociliary. escalator.. Inflammation of the conjunctiva (outermost layer of the eye and inner surface of the eyelids). Classification . Based on cause . Viral conjunctivitis . – adenovirus. Herpetic . keratoconjuctivitis. Dr N. K. . Kansal. Associate Professor. Basic principles. Medications – Can target the skin by either topical/ . intralesional. / systemic routes. I. ntralesional. administration – Additional option for very localized lesions . Shaymaa F. Abbas. MSc Pharmacology. 1. Histamine. is an endogenous substance , widely distributed in the body, . It is called "Autacoid or local hormone, because it acts locally at the site of release. .