Part I DNA Topics addressed in this Unit NGSS MS Topics addressed in this Unit Part I NGSS MS Part I NGSS HS Additional Standards Addressed Additional Standards Addressed Copyright 2010 Ryan P Murphy ID: 484925
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Copyright © 2010 Ryan P. Murphy
Part I: DNASlide2
Topics addressed in this Unit
NGSS MSSlide3
Topics addressed in this Unit Part I
NGSS MS Part ISlide4
NGSS HSSlide5
Additional Standards AddressedSlide6
Additional Standards AddressedSlide7
Copyright © 2010 Ryan P. Murphy
Part I: DNASlide8
RED SLIDE:
These are notes that are very important and should be recorded in your science journal.
Copyright © 2010 Ryan P. MurphySlide9
Slide10
Please use this red lineSlide11
-Please make notes legible and use indentations when appropriate.
Please use this red lineSlide12
-
Please make notes legible and use indentations when appropriate.
Please use this red lineSlide13
-Please make notes legible and use indentations when appropriate. -Example of indent.
Slide14
-Please make notes legible and use indentations when appropriate. -Example of indent. -Skip a line between topics Slide15
-Please make notes legible and use indentations when appropriate. -Example of indent. -Skip a line between topics -Don’t skip pages Slide16
-Please make notes legible and use indentations when appropriate. -Example of indent. -Skip a line between topics -Don’t skip pages -Make visuals clear and well drawn. Slide17
-Please make notes legible and use indentations when appropriate. -Example of indent. -Skip a line between topics -Don’t skip pages -Make visuals clear and well drawn. Slide18
-Please make notes legible and use indentations when appropriate. -Example of indent. -Skip a line between topics -Don’t skip pages -Make visuals clear and well drawn. Please Label
Phosphate Backbone
Double Helix
Nitrogen BaseSlide19
RED SLIDE: These are notes that are very important and should be recorded in your science journal.
BLACK SLIDE: Pay attention, follow directions, complete projects as described and answer required questions neatly.
Copyright © 2010 Ryan P. MurphySlide20
Keep an eye out for “The-Owl” and raise your hand as soon as you see him.He will be hiding somewhere in the slideshow
Copyright © 2010 Ryan P. MurphySlide21
Keep an eye out for “The-Owl” and raise your hand as soon as you see him.He will be hiding somewhere in the slideshow
“Hoot, Hoot”
“Good Luck!”
Copyright © 2010 Ryan P. MurphySlide22
Overview of topics in Part IDNA Extraction from split peaDiscovery of DNA
DNA’s StructureNucleotidesBuilding a DNA modelDNA replicationCell DivisionChromosomesPhases of MitosisSlide23
Overview of topics in Part IDNA Extraction from split pea
Discovery of DNADNA’s StructureNucleotidesBuilding a DNA modelDNA replicationCell DivisionChromosomesPhases of MitosisSlide24
Overview of topics in Part IDNA Extraction from split peaDiscovery of DNA
DNA’s StructureNucleotidesBuilding a DNA modelDNA replicationCell DivisionChromosomesPhases of MitosisSlide25
Overview of topics in Part IDNA Extraction from split pea
Discovery of DNADNA’s StructureNucleotidesBuilding a DNA modelDNA replicationCell DivisionChromosomesPhases of MitosisSlide26
Overview of topics in Part IDNA Extraction from split peaDiscovery of DNA
DNA’s StructureNucleotidesBuilding a DNA modelDNA replicationCell DivisionChromosomesPhases of MitosisSlide27
Overview of topics in Part IDNA Extraction from split peaDiscovery of DNA
DNA’s StructureNucleotidesBuilding a DNA modelDNA replicationCell DivisionChromosomesPhases of MitosisSlide28
Overview of topics in Part IDNA Extraction from split peaDiscovery of DNA
DNA’s StructureNucleotidesBuilding a DNA modelDNA replicationCell DivisionChromosomesPhases of MitosisSlide29
Overview of topics in Part IDNA Extraction from split peaDiscovery of DNA
DNA’s StructureNucleotidesBuilding a DNA modelDNA replicationCell DivisionChromosomesPhases of MitosisSlide30
Overview of topics in Part IDNA Extraction from split peaDiscovery of DNA
DNA’s StructureNucleotidesBuilding a DNA modelDNA replicationCell DivisionChromosomesPhases of MitosisSlide31
Overview of topics in Part IDNA Extraction from split peaDiscovery of DNA
DNA’s StructureNucleotidesBuilding a DNA modelDNA replicationCell DivisionChromosomesPhases of MitosisSlide32
Overview of topics in Part IDNA Extraction from split peaDiscovery of DNA
DNA’s StructureNucleotidesBuilding a DNA modelDNA replicationCell DivisionChromosomesPhases of MitosisSlide33
Overview of topics in Part IDNA Extraction from split peaDiscovery of DNA
DNA’s StructureNucleotidesBuilding a DNA modelDNA replicationCell DivisionChromosomesPhases of MitosisSlide34
Overview of topics in this unitDNA Extraction from split peaDiscovery of DNA
DNA’s StructureNucleotidesBuilding a DNA modelDNA replicationCell DivisionChromosomesPhases of MitosisSlide35
Overview of topics in Part IDNA Extraction from split peaDiscovery of DNA
DNA’s StructureNucleotidesBuilding a DNA modelDNA replicationCell DivisionChromosomesPhases of MitosisSlide36
Overview of topics in Part IDNA Extraction from split peaDiscovery of DNA
DNA’s StructureNucleotidesBuilding a DNA modelDNA replicationCell DivisionChromosomesPhases of MitosisSlide37
Overview of topics in Part IDNA Extraction from split peaDiscovery of DNA
DNA’s StructureNucleotidesBuilding a DNA modelDNA replicationCell DivisionChromosomesPhases of MitosisSlide38
Overview of topics in Part IDNA Extraction from split peaDiscovery of DNA
DNA’s StructureNucleotidesBuilding a DNA modelDNA replicationCell DivisionChromosomesPhases of MitosisSlide39
Overview of topics in Part IDNA Extraction from split peaDiscovery of DNA
DNA’s StructureNucleotidesBuilding a DNA modelDNA replicationCell DivisionChromosomesPhases of MitosisSlide40
Overview of topics in Part IDNA Extraction from split peaDiscovery of DNA
DNA’s StructureNucleotidesBuilding a DNA modelDNA replicationCell DivisionChromosomesPhases of MitosisSlide41
Copyright © 2010 Ryan P. Murphy
DNA and Genetics UnitSlide42
How old are you?
?
Copyright © 2010 Ryan P. MurphySlide43
Answer: Billions of years old.
Copyright © 2010 Ryan P. Murphy
This Product Belongs to Ryan P. Murphy Copyright 2010Slide44
Answer: Billions of years old.
How?Copyright © 2010 Ryan P. Murphy
This Product Belongs to Ryan P. Murphy Copyright 2010Slide45
The back story of our lives are that we are the product of billions of years of evolution.
The very DNA that allows us to pass on our genetic information to our offspring has its roots in primitive microbes that existed billions of years ago.
Copyright © 2010 Ryan P. MurphySlide46
The back story of our lives are that we are the product of billions of years of evolution. The very DNA that allows us to pass on our genetic information to our offspring has its roots in primitive microbes that existed billions of years ago.
Copyright © 2010 Ryan P. MurphySlide47
DNA Extraction Available SheetSlide48
Activity! Extracting the Code of Life.Lab handout can be found in the activities folder.
http://learn.genetics.utah.edu/content/labs/extraction/howto/ (More Information)
The Instructions For LifeSlide49
Activity! DNA ExtractionProcedure: Part I
1.) One class member measures out 100ml of split peas and add to blender.2.) Add 1ml of table salt to blender.3.) Add 200 ml of cold water.4.) Cover and blend on high for 15-20 seconds.5.) Pour contents through strainer into another container (plastic cup).
Copyright © 2010 Ryan P. MurphySlide50
Activity! DNA ExtractionProcedure: Part II
6.) Add 30 ml of liquid detergent and mix in the container.7.) Let the mixture sit for 5-10 minutes (clean up area during this time)8.) Pour the mixture into test tubes equally.9.) Add a pinch of enzymes to each container.
“Gently” very gently swirl for 1 minute.
Copyright © 2010 Ryan P. MurphySlide51
Activity! DNA ExtractionProcedure: Part III
7.) Tilt your test tube and slowly pour rubbing alcohol (70-95% isopropyl or ethyl alcohol) into the tube down the side so that it forms a layer on top of the pea mixture. Pour until you have about the same amount of alcohol in the tube as pea mixture.8.) DNA will rise into the alcohol layer from the pea layer. You can use a wooden stick (cotton swab) or other hook to draw the DNA into the alcohol.
Copyright © 2010 Ryan P. MurphySlide52
Procedure:
1) One class member measures out 100ml of split peas and add to blender.2) Add 1ml of table salt to blender.3) Add 200 ml of cold water.4) Cover and blend on high for 15-20 seconds.5) Pour contents through strainer into another container (plastic cup).6) Add 30 ml of liquid detergent and mix in the container.
7) Let the mixture sit for 5-10 minutes (clean up area during this time).
8) Pour the mixture into test tubes equally.
9) Add a pinch of enzymes to each container.
10) “Gently” very gently swirl for 1 minute.11) Tilt your test tube and slowly pour rubbing alcohol (70-95% isopropyl or ethyl alcohol) into the tube down the side so that it forms a layer on top of the pea mixture. Pour until you have about the same amount of alcohol in the tube as pea mixture.12) DNA will rise into the alcohol layer from the pea layer. You can use a wooden stick (cotton swab) or other hook to draw the DNA into the alcohol.
http://www.biologyjunction.com/extracting_dna.htmSlide53
Activity! DNA ExtractionDirections will be provided.
Copyright © 2010 Ryan P. MurphySlide54
Activity! DNA ExtractionDirections will be provided
.
Copyright © 2010 Ryan P. MurphySlide55
Activity! DNA ExtractionDirections will be provided.
Copyright © 2010 Ryan P. MurphySlide56
Activity! DNA ExtractionDirections will be provided.
Copyright © 2010 Ryan P. MurphySlide57
Activity! DNA ExtractionDirections will be provided.
Copyright © 2010 Ryan P. MurphySlide58
Activity! DNA ExtractionDirections will be provided.
Copyright © 2010 Ryan P. MurphySlide59
Copyright © 2010 Ryan P. MurphySlide60
The meat tenderizer was added to break down the protein
that the DNA is wrapped around. This allows the protein to be extracted.
Copyright © 2010 Ryan P. MurphySlide61
Did your final extraction look like this?
This is DNA, the genetic molecules in each cell. Copyright © 2010 Ryan P. Murphy
Learn more about DNA extraction at…
http://www.chem.umn.edu/services/lecturedemo/info/DNA.htmSlide62
DNA-
---
Copyright © 2010 Ryan P. MurphySlide63
DNA: Deoxyrib
ose Nucleic Acid.
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Shape is called double helix.
Copyright © 2010 Ryan P. MurphySlide65Slide66
DNA is a polymer (Long molecule).
Copyright © 2010 Ryan P. MurphySlide67
DNA is a polymer (Long molecule).
Copyright © 2010 Ryan P. Murphy
Chromosome
A tightly wound package of DNA.Slide68
Activity! How long is the DNA chain inside of a cell?
Take your best guess.
Copyright © 2010 Ryan P. MurphySlide69
Answer: The DNA in cells can hold lots of information and are very long.
Each cell has about 1.8 meters (6 feet) of DNA.
1.8 meters of DNA
Copyright © 2010 Ryan P. MurphySlide70
Video! DNA wrapping. Shows how 1.8 meters of DNA can be found in a single cell.
http://www.youtube.com/watch?v=AF2wwMReTf8
Copyright © 2010 Ryan P. MurphySlide71
The units of DNA are called nucleotides.
Copyright © 2010 Ryan P. MurphySlide72
DNA has the information for our cells to make proteins.
Copyright © 2010 Ryan P. MurphySlide73
DNA has the information for our cells to make proteins.
Copyright © 2010 Ryan P. MurphySlide74
DNA has the information for our cells to make proteins.
Copyright © 2010 Ryan P. Murphy
Keep your
hard copy
safe in the nucleusSlide75
DNA has the information for our cells to make proteins.
Copyright © 2010 Ryan P. Murphy
Keep your
hard copy
safe in the nucleusSlide76
DNA has the information for our cells to make proteins.
Copyright © 2010 Ryan P. Murphy
Keep your
hard copy
safe in the nucleusSlide77
DNA has the information for our cells to make proteins.
Copyright © 2010 Ryan P. Murphy
Keep your
hard copy
safe in the nucleusSlide78
DNA has the information for our cells to make proteins.
Copyright © 2010 Ryan P. Murphy
Keep your
hard copy
safe in the nucleusSlide79
DNA has the information for our cells to make proteins.
Copyright © 2010 Ryan P. Murphy
Keep your
hard copy
safe in the nucleusSlide80
DNA has the information for our cells to make proteins.
Copyright © 2010 Ryan P. Murphy
Keep your
hard copy
safe in the nucleus
Except
ProteinsSlide81
DNA through transcription makes mRNA.mRNA = Messenger RNA.
Copyright © 2010 Ryan P. MurphySlide82
Transcription, Learn more at
http://biology.about.com/od/cellularprocesses/ss/Dna-Transcription.htmSlide83
mRNA through translation makes proteins with the help of ribosomes
.
Copyright © 2010 Ryan P. MurphySlide84Slide85
NOT TO SCALESlide86Slide87Slide88Slide89Slide90Slide91Slide92Slide93Slide94Slide95
.
Copyright © 2010 Ryan P. Murphy
Nuclear
Membrane
Ribosomes
Inside
Nucleus
RNA through
Nuclear Pore
Outside of
NucleusSlide96
.
Copyright © 2010 Ryan P. Murphy
Nuclear
Membrane
Ribosomes
Inside
Nucleus
RNA through
Nuclear Pore
Outside of
NucleusSlide97
.
Copyright © 2010 Ryan P. Murphy
Nuclear
Membrane
Ribosomes
Inside
Nucleus
RNA through
Nuclear Pore
Outside of
NucleusSlide98
.
Copyright © 2010 Ryan P. Murphy
Nuclear
Membrane
Ribosomes
Inside
Nucleus
RNA through
Nuclear Pore
Outside of
NucleusSlide99
.
Copyright © 2010 Ryan P. Murphy
Nuclear
Membrane
Ribosomes
Inside
Nucleus
RNA through
Nuclear Pore
Outside of
NucleusSlide100
.
Copyright © 2010 Ryan P. Murphy
Nuclear
Membrane
Ribosomes
Inside
Nucleus
RNA through
Nuclear Pore
Outside of
NucleusSlide101
.
Copyright © 2010 Ryan P. Murphy
Nuclear
Membrane
Ribosomes
Inside
Nucleus
RNA through
Nuclear Pore
Outside of
NucleusSlide102Slide103
.
Copyright © 2010 Ryan P. Murphy
Nuclear
Membrane
Ribosomes
Inside
Nucleus
RNA through
Nuclear Pore
Outside of
NucleusSlide104
.
Copyright © 2010 Ryan P. Murphy
Nuclear
Membrane
Ribosomes
Inside
Nucleus
RNA through
Nuclear Pore
Outside of
NucleusSlide105
.
Copyright © 2010 Ryan P. Murphy
Nuclear
Membrane
Ribosomes
Inside
Nucleus
RNA through
Nuclear Pore
Outside of
NucleusSlide106
.
Copyright © 2010 Ryan P. Murphy
Nuclear
Membrane
Ribosomes
Inside
Nucleus
RNA through
Nuclear Pore
Outside of
NucleusSlide107
.
Copyright © 2010 Ryan P. Murphy
Nuclear
Membrane
Ribosomes
Inside
Nucleus
RNA through
Nuclear Pore
Outside of
NucleusSlide108Slide109
.
Copyright © 2010 Ryan P. Murphy
Nuclear
Membrane
Ribosomes
RNA through
Nuclear PoreSlide110
.
Copyright © 2010 Ryan P. Murphy
Nuclear
Membrane
Ribosomes
RNA through
Nuclear PoreSlide111
.
Copyright © 2010 Ryan P. Murphy
Nuclear
Membrane
Ribosomes
RNA through
Nuclear PoreSlide112
.
Copyright © 2010 Ryan P. Murphy
Nuclear
Membrane
Ribosomes
RNA through
Nuclear PoreSlide113
.
Copyright © 2010 Ryan P. Murphy
Nuclear
Membrane
Ribosomes
RNA through
Nuclear PoreSlide114Slide115
.
Copyright © 2010 Ryan P. Murphy
Nuclear
Membrane
Ribosomes
Inside
Nucleus
RNA through
Nuclear Pore
Outside of
NucleusSlide116
.
Copyright © 2010 Ryan P. Murphy
Nuclear
Membrane
Ribosomes
Inside
Nucleus
RNA through
Nuclear Pore
Outside of
NucleusSlide117
.
Copyright © 2010 Ryan P. Murphy
Nuclear
Membrane
Ribosomes
Inside
Nucleus
RNA through
Nuclear Pore
Outside of
NucleusSlide118
.
Copyright © 2010 Ryan P. Murphy
Nuclear
Membrane
Ribosomes
Inside
Nucleus
RNA through
Nuclear Pore
Outside of
NucleusSlide119
.
Copyright © 2010 Ryan P. Murphy
Nuclear
Membrane
Ribosomes
Inside
Nucleus
RNA through
Nuclear Pore
Outside of
NucleusSlide120
.
Copyright © 2010 Ryan P. Murphy
Nuclear
Membrane
Ribosomes
Inside
Nucleus
RNA through
Nuclear Pore
Outside of
NucleusSlide121
.
Copyright © 2010 Ryan P. Murphy
Nuclear
Membrane
Ribosomes
Inside
Nucleus
RNA through
Nuclear Pore
Outside of
NucleusSlide122
.
Copyright © 2010 Ryan P. Murphy
Nuclear
Membrane
Ribosomes
Inside
Nucleus
RNA through
Nuclear Pore
Outside of
NucleusSlide123
Video Link! Transcription and Translation.http://www.youtube.com/watch?v=41_Ne5mSlide124Slide125
Important Note: Most DNA is found in the nucleus. Slide126
Important Note: Most DNA is found in the nucleus. Slide127
Important Note: Most DNA is found in the nucleus. Small amounts of DNA are found in the mitochondria organelle (
mtDNA)
Learn more
abaout
mtDNA at http://en.wikipedia.org/wiki/Mitochondrial_DNASlide128
Important Note: Most DNA is found in the nucleus. Small amounts of DNA are found in the mitochondria organelle (
mtDNA)
Learn more
http
://en.wikipedia.org/wiki/Mitochondrial_DNASlide129
You can now do this question for homework.Slide130
Watson and Crick (1953) Discovered structure of DNA.
One of the most important biological discoveries in the last 100 years.
Copyright © 2010 Ryan P. MurphySlide131
Watson and Crick (1953) Discovered structure of DNA.
One of the most important biological discoveries in the last 100 years.
Copyright © 2010 Ryan P. MurphySlide132Slide133
Watson and Crick were able to figure out that one strand went up and one went down.Slide134
Watson and Crick were able to figure out that one strand went up and one went down.
Upstream
5’
3’Slide135
Watson and Crick were able to figure out that one strand went up and one went down.
Upstream
5’
3’
Downstream
3’
5’Slide136
Watson and Crick were able to figure out that one strand went up and one went down.
Watson and Crick also found that if they paired
Thymine
with
Adenine
and
Guanine
with
Cytosine
DNA would look uniform.
Upstream
5’
3’
Downstream
3’
5’Slide137
Watson and Crick were able to figure out that one strand went up and one went down.
Watson and Crick also found that if they paired
Thymine
with
Adenine
and
Guanine
with
Cytosine
DNA would look uniform.
Learn more at…
http://www.nobelprize.org/educational/medicine/dna_double_helix/readmore.html?referer=www.clickfind.com.au
Upstream
5’
3’
Downstream
3’
5’Slide138Slide139
James WatsonSlide140
James Watson
Francis CrickSlide141
“Am I Watson or Crick?”Slide142
“I am James Watson.”Slide143
“Am I Watson or Crick?”Slide144
“I am Francis Crick.”Slide145Slide146
Francis CrickSlide147
Francis CrickSlide148
Francis Crick
James WatsonSlide149Slide150
James WatsonSlide151
James WatsonSlide152
James Watson
Francis CrickSlide153
“What year did we discover the structure of DNA.”Slide154
1953Slide155
Activity Reading. Who discovered DNA?Please complete 3 of the 5 questions on the last page.
Caution!
Difficult Reading AheadSlide156
Please answer 3 of the 5 questions below from the difficult reading.
1.) Name four people in this article and how they contributed to the discovery of DNA’s structure?2.) What role did Maurice Wilkins play in the discovery of DNA’s structure?3.) What two things in DNA’s structure did Watson and Crick figure out that Rosalind Franklin missed?4.) Describe the relationship between of Rosalind Franklin to Watson, Crick, and Wilkins?
5.) How does getting things done first / taking risks relate to this article?
6.) Find three words that you did not know from the reading and use a dictionary / resource to define them?
7.) Create a comic book sequence between Rosalind Franklin, Maurice Wilkins, James Watson, and Francis Crick from something discussed in the article.Slide157
Rosalind Franklin? Who is she?
Copyright © 2010 Ryan P. MurphySlide158
She took X-Ray pictures of DNA’s structure and lectured about phosphate being a part of the outside of the molecule.
Copyright © 2010 Ryan P. MurphySlide159
She took X-Ray pictures of DNA’s structure and lectured about phosphate being a part of the outside of the molecule.
Watson attended her lecture.
Copyright © 2010 Ryan P. MurphySlide160
Watson and Crick used her photograph and lectures to create a failed model of the helix.
Copyright © 2010 Ryan P. MurphySlide161
Watson and Crick used her photograph and lectures to create a failed model of the helix.
Maurice Wilkins who was working with Rosalind Franklin showed Watson her experiments.Copyright © 2010 Ryan P. MurphySlide162
In 1962,
Copyright © 2010 Ryan P. MurphySlide163
In 1962, Watson,
Copyright © 2010 Ryan P. MurphySlide164
In 1962, Watson,
Crick, Copyright © 2010 Ryan P. MurphySlide165
In 1962, Watson,
Crick, and Wilkins
Copyright © 2010 Ryan P. MurphySlide166
In 1962, Watson,
Crick, and Wilkins won the Nobel Prize for physiology/medicine.
Copyright © 2010 Ryan P. MurphySlide167
In 1962, Watson,
Crick, and Wilkins won the Nobel Prize for physiology/medicine.
Copyright © 2010 Ryan P. MurphySlide168
In 1962, Watson, Crick, and Wilkins won the Nobel Prize for physiology/medicine.
Franklin had died of Ovarian Cancer.Copyright © 2010 Ryan P. MurphySlide169
In 1962, Watson, Crick, and Wilkins won the Nobel Prize for physiology/medicine,
Franklin had died of Ovarian Cancer.The cancer that killed her may have been caused by working with X-Rays.Slide170
In 1962, Watson, Crick, and Wilkins won the Nobel Prize for physiology/medicine,
Franklin had died of Ovarian Cancer.The cancer that killed her may have been caused by working with X-Rays.The Nobel Prize only goes to living recipients, and can only be shared among three winners. Slide171Slide172
Copyright © 2010 Ryan P. MurphySlide173
Copyright © 2010 Ryan P. MurphySlide174
Copyright © 2010 Ryan P. MurphySlide175
Copyright © 2010 Ryan P. MurphySlide176
Copyright © 2010 Ryan P. MurphySlide177
Copyright © 2010 Ryan P. MurphySlide178
Who thinks we should give an honorary Nobel Prize to Rosalind Franklin?
Copyright © 2010 Ryan P. MurphySlide179
Who thinks we should give an honorary Nobel Prize to Rosalind Franklin?
Lets give a short round of applause to Rosalind Franklin.“Our Lady of DNA”
Copyright © 2010 Ryan P. MurphySlide180
Who thinks we should give an honorary Nobel Prize to Rosalind Franklin?
Lets give a short round of applause to Rosalind Franklin.“Our Lady of DNA”
Copyright © 2010 Ryan P. Murphy
Learn more about Rosalind Franklin at…
http://www.biography.com/people/rosalind-franklin-9301344Slide181Slide182Slide183Slide184Slide185Slide186Slide187Slide188
Maurice WilkinsSlide189
You can now do this question for homework.Slide190
Activity! Draw DNA in Detail.
Copyright © 2010 Ryan P. MurphySlide191
Copyright © 2010 Ryan P. MurphySlide192
Copyright © 2010 Ryan P. MurphySlide193
Copyright © 2010 Ryan P. MurphySlide194
Copyright © 2010 Ryan P. MurphySlide195
A
A
A
G
T
C
T
T
Copyright © 2010 Ryan P. MurphySlide196
Each unit called a nucleotide of DNA consists of 3 parts.-
--
Copyright © 2010 Ryan P. MurphySlide197
A
A
A
G
T
C
T
T
NucleotideSlide198
Phosphate backbone
Copyright © 2010 Ryan P. MurphySlide199
A
A
A
G
T
C
T
T
Phosphate Backbone
Copyright © 2010 Ryan P. MurphySlide200
A 5-carbon sugar (deoxyribose)
Copyright © 2010 Ryan P. MurphySlide201
A
A
A
G
T
C
T
T
Ribose Sugar
Copyright © 2010 Ryan P. MurphySlide202
A nitrogen base attached to the sugar
Copyright © 2010 Ryan P. MurphySlide203
A
A
A
G
T
C
T
T
Nitrogen Base
Copyright © 2010 Ryan P. MurphySlide204
Copyright © 2010 Ryan P. MurphySlide205
Copyright © 2010 Ryan P. MurphySlide206
Copyright © 2010 Ryan P. MurphySlide207
Copyright © 2010 Ryan P. MurphySlide208
Copyright © 2010 Ryan P. MurphySlide209
Nucleic Acids – P O N C H (Nucleotide)
Copyright © 2010 Ryan P. MurphySlide210
Nucleic Acids –
P O N C H (Nucleotide)
Copyright © 2010 Ryan P. Murphy
PhosphorusSlide211
Nucleic Acids –
P O N C H (Nucleotide)
Copyright © 2010 Ryan P. Murphy
PhosphorusSlide212
Nucleic Acids –
P O N C H (Nucleotide)
Copyright © 2010 Ryan P. Murphy
Phosphorus
OxygenSlide213
Nucleic Acids –
P O N C H (Nucleotide)
Copyright © 2010 Ryan P. Murphy
Phosphorus
OxygenSlide214
Nucleic Acids –
P O N
C H (Nucleotide)
Copyright © 2010 Ryan P. Murphy
Phosphorus
Oxygen
NitrogenSlide215
Nucleic Acids –
P O N
C H (Nucleotide)
Copyright © 2010 Ryan P. Murphy
Phosphorus
Oxygen
NitrogenSlide216
Nucleic Acids –
P O N
C
H (Nucleotide)
Copyright © 2010 Ryan P. Murphy
Phosphorus
Oxygen
NitrogenSlide217
Nucleic Acids –
P O N
C
H (Nucleotide)
Copyright © 2010 Ryan P. Murphy
Phosphorus
Oxygen
Nitrogen
CarbonSlide218
Nucleic Acids –
P O N
C
H (Nucleotide)
Copyright © 2010 Ryan P. Murphy
Phosphorus
Oxygen
Carbon
Nitrogen
HydrogenSlide219
Nucleic Acids –
P O N
C
H (Nucleotide)
Copyright © 2010 Ryan P. Murphy
Phosphorus
Oxygen
Nitrogen
Carbon
HydrogenSlide220
There are four different types of nucleotides found in DNA
A is for adenine G is for guanine C is for cytosine T is for thymine
Copyright © 2010 Ryan P. MurphySlide221
There are four different types of nucleotides found in DNA
A is for adenine G is for guanine C is for cytosine T is for thymine
Copyright © 2010 Ryan P. MurphySlide222
There are four different types of nucleotides found in DNA
A is for adenine G is for guanine C is for cytosine T is for thymine
Copyright © 2010 Ryan P. MurphySlide223
There are four different types of nucleotides found in DNA
A is for adenine G is for guanine C is for cytosine T is for thymine
Copyright © 2010 Ryan P. MurphySlide224
There are four different types of nucleotides found in DNA
A is for adenine G is for guanine C is for cytosine T is for thymine
Copyright © 2010 Ryan P. MurphySlide225
There are four different types of nucleotides found in DNA
A is for adenine G is for guanine C is for cytosine T is for thymine
Copyright © 2010 Ryan P. Murphy
Learn more about the structure of DNA at
http://ghr.nlm.nih.gov/handbook/basics/dnaSlide226
Copyright © 2010 Ryan P. MurphySlide227
Copyright © 2010 Ryan P. MurphySlide228
Copyright © 2010 Ryan P. MurphySlide229
Copyright © 2010 Ryan P. MurphySlide230
A
A
A
G
T
C
T
T
Copyright © 2010 Ryan P. MurphySlide231
A
A
A
G
T
C
T
T
Nucleotide
Copyright © 2010 Ryan P. MurphySlide232
A
A
A
G
T
C
T
T
Phosphate Backbone
Copyright © 2010 Ryan P. MurphySlide233
A
A
A
G
T
C
T
T
Ribose Sugar
Copyright © 2010 Ryan P. MurphySlide234
A
A
A
G
T
C
T
T
Nitrogen Base
Copyright © 2010 Ryan P. MurphySlide235
Can you touch the following on this moving image of the double helix.
Copyright © 2010 Ryan P. MurphySlide236
Can you touch the following on this moving image of the double helix.
Phosphate Backbone
Copyright © 2010 Ryan P. MurphySlide237
Can you touch the following on this moving image of the double helix.
Phosphate Backbone
Ribose sugar
Copyright © 2010 Ryan P. MurphySlide238
Can you touch the following on this moving image of the double helix.
Phosphate Backbone
Ribose sugar
Nitrogen Base
Copyright © 2010 Ryan P. MurphySlide239
A goes with TC goes with G
WRONG! T – C or G - A
Copyright © 2010 Ryan P. MurphySlide240
A goes with TC goes with G
WRONG! T – C or G - A
Copyright © 2010 Ryan P. MurphySlide241
A goes with TC goes with G
WRONG! T – C or G - A
Copyright © 2010 Ryan P. MurphySlide242
A goes with TC goes with G
WRONG! T – C or G - A
Copyright © 2010 Ryan P. MurphySlide243
Activity! Which of the base pairs below is incorrect.
Adenine –- Thymine Guanine –- Cytosine Thymine - AdenineThymine - AdenineCytosine - Guanine
Adenine –- Thymine
Guanine –- Cytosine
Thymine - Adenine
Adenine -- Thymine Cytosine – AdenineAdenine – Thymine Adenine – Thymine Guanine – Cytosine
Copyright © 2010 Ryan P. MurphySlide244
Answers! Which of the base pairs below is incorrect.
Adenine –- Thymine Guanine –- Cytosine Thymine - AdenineThymine - Adenine
Cytosine - Guanine
Adenine –- Thymine
Guanine –- Cytosine
Thymine - AdenineAdenine -- Thymine Cytosine – AdenineAdenine – Thymine Adenine – Thymine Guanine – Cytosine
Same challenge next slide
Copyright © 2010 Ryan P. MurphySlide245
Adenine –- Thymine
Guanine –- Cytosine
Thymine - Adenine
Thymine - Adenine
Cytosine - Guanine
Adenine –- Thymine
Guanine –- Cytosine
Thymine - Adenine
Adenine -- Thymine
Cytosine – Guanine
Adenine – Thymine
Adenine – Thymine
Guanine – Cytosine
Adenine –- Thymine
Guanine –- Cytosine
Thymine - Adenine
Thymine - Adenine
Cytosine - Guanine
Adenine –- Thymine
Guanine –- Cytosine
Thymine - Adenine
Adenine -- Thymine
Cytosine – Guanine
Adenine – Thymine
Adenine – Thymine
Guanine – Cytosine
Adenine –- Thymine
Guanine –- Cytosine
Thymine - Adenine
Thymine - Adenine
Cytosine - Guanine
Adenine –- Thymine
Guanine –- Cytosine
Thymine - Adenine
Adenine -- Thymine
Cytosine – Guanine
Adenine – Thymine
Adenine – Thymine
Guanine – Cytosine
Adenine –- Thymine
Guanine –- Cytosine
Thymine - Adenine
Thymine - Adenine
Cytosine - Guanine
Adenine –- Thymine
Guanine –- Cytosine
Thymine - Adenine
Adenine -- Thymine
Cytosine – Guanine
Adenine – Thymine
Adenine – Thymine
Guanine – Cytosine
Adenine –- Thymine
Guanine –- Cytosine
Thymine - Adenine
Thymine - Adenine
Thymine - Adenine
Thymine - Adenine
Cytosine - Guanine
Adenine –- Thymine
Guanine –- Cytosine
Thymine - Adenine
Adenine -- Thymine
Cytosine – Guanine
Adenine – Thymine
Adenine – Thymine
Guanine – Cytosine
Adenine –- Thymine
Guanine –- Cytosine
Thymine - Adenine
Thymine - Adenine
Cytosine - Guanine
Adenine –- Thymine
Guanine –- Cytosine
Thymine - Adenine
Adenine -- Thymine
Cytosine – Guanine
Adenine – Thymine
Adenine – Thymine
Guanine – Cytosine
Cytosine - Guanine
Adenine –- Thymine
Guanine –- Cytosine
Thymine - Adenine
Thymine - Adenine
Thymine - Adenine
Cytosine - Guanine
Adenine –- Thymine
Guanine –- Cytosine
Thymine - Adenine
Adenine -- Thymine
Cytosine – Guanine
Adenine – Thymine
Adenine – Adenine
Guanine – Cytosine
Adenine –- Thymine
Guanine –- Cytosine
Thymine - Adenine
Thymine - Adenine
Cytosine - Guanine
Adenine –- Thymine
Guanine –- Cytosine
Thymine - Adenine
Adenine -- Thymine
Cytosine – Guanine
Adenine – Thymine
Adenine – Thymine
Guanine – Cytosine
Adenine -- Thymine
Cytosine – Guanine
Adenine – Thymine
Adenine – Thymine
Copyright © 2010 Ryan P. MurphySlide246
Adenine –- Thymine
Guanine –- Cytosine
Thymine - Adenine
Thymine - Adenine
Cytosine - Guanine
Adenine –- Thymine
Guanine –- Cytosine
Thymine - Adenine
Adenine -- Thymine
Cytosine – Guanine
Adenine – Thymine
Adenine – Thymine
Guanine – Cytosine
Adenine –- Thymine
Guanine –- Cytosine
Thymine - Adenine
Thymine - Adenine
Cytosine - Guanine
Adenine –- Thymine
Guanine –- Cytosine
Thymine - Adenine
Adenine -- Thymine
Cytosine – Guanine
Adenine – Thymine
Adenine – Thymine
Guanine – Cytosine
Adenine –- Thymine
Guanine –- Cytosine
Thymine - Adenine
Thymine - Adenine
Cytosine - Guanine
Adenine –- Thymine
Guanine –- Cytosine
Thymine - Adenine
Adenine -- Thymine
Cytosine – Guanine
Adenine – Thymine
Adenine – Thymine
Guanine – Cytosine
Adenine –- Thymine
Guanine –- Cytosine
Thymine - Adenine
Thymine - Adenine
Cytosine - Guanine
Adenine –- Thymine
Guanine –- Cytosine
Thymine - Adenine
Adenine -- Thymine
Cytosine – Guanine
Adenine – Thymine
Adenine – Thymine
Guanine – Cytosine
Adenine –- Thymine
Guanine –- Cytosine
Thymine - Adenine
Thymine - Adenine
Thymine - Adenine
Thymine - Adenine
Cytosine - Guanine
Adenine –- Thymine
Guanine –- Cytosine
Thymine - Adenine
Adenine -- Thymine
Cytosine – Guanine
Adenine – Thymine
Adenine – Thymine
Guanine – Cytosine
Adenine –- Thymine
Guanine –- Cytosine
Thymine - Adenine
Thymine - Adenine
Cytosine - Guanine
Adenine –- Thymine
Guanine –- Cytosine
Thymine - Adenine
Adenine -- Thymine
Cytosine – Guanine
Adenine – Thymine
Adenine – Thymine
Guanine – Cytosine
Cytosine - Guanine
Adenine –- Thymine
Guanine –- Cytosine
Thymine - Adenine
Thymine - Adenine
Thymine - Adenine
Cytosine - Guanine
Adenine –- Thymine
Guanine –- Cytosine
Thymine - Adenine
Adenine -- Thymine
Cytosine – Guanine
Adenine – Thymine
Adenine – Adenine
Guanine – Cytosine
Adenine –- Thymine
Guanine –- Cytosine
Thymine - Adenine
Thymine - Adenine
Cytosine - Guanine
Adenine –- Thymine
Guanine –- Cytosine
Thymine - Adenine
Adenine -- Thymine
Cytosine – Guanine
Adenine – Thymine
Adenine – Thymine
Guanine – Cytosine
Adenine -- Thymine
Cytosine – Guanine
Adenine – Thymine
Adenine – Thymine
Copyright © 2010 Ryan P. MurphySlide247
End of Preview
Hundreds of more slides,
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notes, review games,
rubrics, and much more
on the full version of this unit
and larger curriculum.Slide248
This PowerPoint is one small part of my DNA and Genetics Unit.
This unit includes…A five part 3,000 slide PowerPoint roadmap.14 page bundled homework package, answer keys, lesson notes, rubrics, materials list, guide, and much more.
PowerPoint Review Game, games, flashcards, crosswords, and more
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http://sciencepowerpoint.com/DNA_Genetics_Unit.htmlSlide249
DNA Review Game
Study!Slide250
“AYE” Advance Your Exploration ELA and Literacy Opportunity WorksheetVisit some of the many provided links or..
Articles can be found at (w/ membership to NABT and NSTA)http://www.nabt.org/websites/institution/index.php?p=1http://learningcenter.nsta.org/browse_journals.aspx?journal=tst
Please visit at least one of the “learn more”
educational
links provided in this unit and complete this worksheet. Slide251
“AYE” Advance Your Exploration ELA and Literacy Opportunity Worksheet
Visit some of the many provided links or..Articles can be found at (w/ membership to NABT and NSTA)http://www.nabt.org/websites/institution/index.php?p=1http://learningcenter.nsta.org/browse_journals.aspx?journal=tstSlide252
DNA and Genetics UnitSlide253
DNA and Genetics Unit
Areas of Focus within The DNA and Genetics Unit:
DNA, DNA Extraction, Structure of DNA, Discovery of the Double Helix, Rosalind Franklin, Nucleotides, RNA, Cell Division, Mitosis, Phases of Mitosis, Chromosomes, Cancer, Ways to Avoid Cancer, What is Inside a Cigarette?, Facts about Smoking?, Anti-Smoking Ads, Meiosis, Phases in Meiosis,
Mendelian
Genetics,
Gregor
Mendel,
Punnett
Squares, Probability,
Dihybrid
Cross,
Codominance
, Bio-Ethics, Stem Cell Debate, Cloning Debate
Full Unit found at…
http://sciencepowerpoint.com/DNA_Genetics_Unit.htmlSlide254Slide255Slide256
Additional Standards AddressedSlide257
Additional Standards AddressedSlide258
Please visit the links below to learn more about each of the units in this curriculum
These units take me about four years to complete with my students in grades 5-10.Earth Science UnitsExtended
Tour Link and Curriculum Guide
Geology Topics Unit
http://sciencepowerpoint.com/Geology_Unit.html
Astronomy Topics Unit
http://sciencepowerpoint.com/Astronomy_Unit.htmlWeather and Climate Unit
http://sciencepowerpoint.com/Weather_Climate_Unit.html
Soil Science,
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http://sciencepowerpoint.com/Soil_and_Glaciers_Unit.html
Water
Unit
http://sciencepowerpoint.com/Water_Molecule_Unit.html
Rivers Unit
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= Easier = More Difficult = Most Difficult
5
th
– 7
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grade 6
th
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grade 8
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th
gradeSlide259
Physical Science Units
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Motion
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Unithttp://sciencepowerpoint.com/Newtons_Laws_Motion_Machines_Unit.html
Matter, Energy, Envs. Unithttp://sciencepowerpoint.com/Energy_Topics_Unit.html
Atoms
and Periodic Table Unit
http://sciencepowerpoint.com/Atoms_Periodic_Table_of_Elements_Unit.html
Life Science Units
Extended
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Human
Body / Health Topics
http://sciencepowerpoint.com/Human_Body_Systems_and_Health_Topics_Unit.html
DNA
and Genetics Unit
http://sciencepowerpoint.com/DNA_Genetics_Unit.html
Cel
l Biology Unit
http://sciencepowerpoint.com/Cellular_Biology_Unit.html
Infectious
Diseases Unit
http://sciencepowerpoint.com/Infectious_Diseases_Unit.html
Taxonomy
and Classification Unit
http://sciencepowerpoint.com/Taxonomy_Classification_Unit.html
Evolution
/ Natural Selection Unit
http://sciencepowerpoint.com/Evolution_Natural_Selection_Unit.html
Botany
Topics Unit
http://sciencepowerpoint.com/Plant_Botany_Unit.html
Ecology Feeding Levels
Unit
http://sciencepowerpoint.com/Ecology_Feeding_Levels_Unit.htm
Ecology Interactions Unit
http://sciencepowerpoint.com/Ecology_Interactions_Unit.html
Ecology Abiotic Factors
Unit
http://sciencepowerpoint.com/Ecology_Abiotic_Factors_Unit.htmlSlide260
Thank you for your time and interest in this curriculum tour. Please visit the welcome / guide on how a unit works and link to the many unit previews to see the PowerPoint slideshows, bundled homework, review games, unit notes, and much more. Thank you for your interest and please feel free to contact me with any questions you may have. Best wishes.
Sincerely,Ryan Murphy
M.Ed
ryemurf@gmail.comSlide261
The entire four year curriculum can be found at...
http://sciencepowerpoint.com/ Please feel free to contact me with any questions you may have. Thank you for your interest in this curriculum.
Sincerely,
Ryan Murphy
M.Ed
www.sciencepowerpoint@gmail.com