PDF-T cell recognition of non-peptidic antigens in infectious diseases ...

Amit Singhal Lucia Mori Gennaro De Libero SIgN Singapore Immunology Network ASTAR Agency for Science Technology Research Singapore Experimental Immunology Departme. What is an Infectious Disease?. Any disease that is caused by an agent that has invaded the body.. These are caused by:. Person to person contact. Food and water. Animals. Something in the environment. The epidemiological . transition model.  . The . replacement of infectious diseases by chronic diseases over time due to expanded public health and sanitation.. Define:. Infectious disease:. Chronic disease: . Pathogenicity . of Infectious . Diseases. PATHOGEN. ENVIRONMENT. HOST. DISEASE. . TRIAD. . Host. -. Parasite Interactions. OTHER MICROBES. Microbial Interactions. KOCH'S POSTULATES. Four . criteria that were established by Robert Koch to identify the . Lesson Objectives. :. After finishing today’s lesson, you will be able to. :. list . a number of globally significant infectious diseases and be able to explain how they impact mortality. .. explain . database. 10/4/2014. 1. Presenter Disclosures. I . developed. “IDdx: Infectious Disease Queries” which is currently a free download from . Apple Store. (. iPhone. or . iPad. ) and . Google Play. immunopathology. concerns disorders caused by alterations of the immune response. 3 main categories of alterations:. . excessive response hypersensitivity reactions. inappropriate . . response . POC/Title and or Institute/Website. : Natalia Kruchinin . Ph.D., . NIAID,NIH SBIR/STTR . Program . Coordinator email: . kruchininn@niaid.nih.gov. http. ://. www.niaid.nih.gov/researchfunding/sb/Pages/default.aspx. DOREEN SITALI. SCHOOL OF PUBLIC HEALTH. DEPT. OF HEALTH PROMOTION AND EDUCATION. Introduction. . Global eradication of smallpox in 1977 and discovery of antibiotics led to optimism and complacency that infectious diseases as public health problems could be eradicated or eliminated. Characteristics of Infectious Diseases. Factors that can influence exposure to, and development of, an infectious disease:. Immune status of the individual (host).. Overall incidence of an organism in the general population.. Grade Health. Mrs. . . Eggler. Infectious Diseases. A.K.A., Communicable Diseases. Infectious Diseases . caused by organisms that are so small you need a microscope to see them.. Microorganisms. are the organisms that are so small you need a microscope to see them.. Note the difference between the leading cause of death in the US in 1900 and 2000. 1900. Pneumonia and flu. Tuberculosis. Infectious diarrhea. 2000. Heart disease. Cancer. Stroke. Were any of the leading causes of death in 2000 infectious diseases? Why do you think this is the case?. Dr. Murtada . Mustafa Gaber. Assistant professor of pediatric . nursing. University of BISHA- KSA. . Learning objectives . By the end of this lecture the student should be able to. :. Define infectious childhood disease.. An . antigen. is anything that elicits an adaptive immune response. These are molecules that trigger a specific immune response, eg., components of bacterial cell wall, capsule, pili, flagella, external and internal proteins of viruses, fungi and protozoa, toxins, nonself foreign substances like proteins, nucleoproteins, polysaccharides, some glycoproteins. .. . Paul Ehrlich had first introduced the concept of autoimmunity; he termed this condition as “horror . autotoxicus. ”.. AUTOIMMUNITY. Normally immune system does not react to its own antigens due to a protective mechanism called tolerance. .