PPT-22.4 Glycolysis: Oxidation of Glucose

Author : mitsue-stanley | Published Date : 2018-02-19

Glucose in the bloodstream enters our cells where it undergoes degradation in a pathway called glycolysis Glucose obtained from the digestion of polysaccharides

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22.4 Glycolysis: Oxidation of Glucose: Transcript


Glucose in the bloodstream enters our cells where it undergoes degradation in a pathway called glycolysis Glucose obtained from the digestion of polysaccharides is degraded in glycolysis to pyruvate. WOW do I Need Energy . ATP. All cells need energy. The most common form of cellular energy is ATP. Below is ATP. It is the negative phosphate groups that give this molecule energy as it becomes unstable. When the phosphate is transferred to other molecules, those molecules have energy because they become unstable.. Chapter 6. What is ATP? . Analogy with the coins and the bending machine . How does it function like a rechargeable battery? . RECHARGING ATP. Occurs in the Mitochondria . How do we obtain the energy from GLUCOSE to make ATP? . In glycolysis, these enzymes are . Hexokinase. Phosphofructokinase. P. yruvate kinase. Phosphofructokinase is the key regulator of glycolysis in mammals. The enzyme is allosterically inhibited by ATP and allosterically stimulated by AMP.. Glycolysis . is the breakdown or catabolism of a six carbon glucose molecule in a series of enzyme catalyzed reactions to give 2 molecules of pyruvate which is a 3 carbon compound. Glycolysis takes place in all the cells in the cytosol . During the sequential reactions of glycolysis some of the free energy is stored in the form of ATP and NADH. . Chapter 16, . Stryer. Short Course. Glycolysis Expectations. Memorize/learn Figure . 16.1. Know overall reaction and stages. Explain . chemical/physiological purpose . of each . step. Learn structures. 1. How . many NADH are produced . . in . glycolysis per glucose?. (a) 1. (b) 2. (c) 4. (d) 8. 2. Which . one of the following molecules . in. . . glycolysis donates a phosphate group . to. . Part II. Dr. Kevin Ahern. Glycolysis. Summary. Glucose 2 ADP 2P. i. 2 NAD. . Yields. 2 Pyruvate 2 ATP 2 NADH 2 H. . 2 H. 2. O . Glycolysis. Fermentation in Yeast/Bacteria. Glucose. GA3P. Chapter 14-23. Overview of Metabolic Pathways-I. Lecture 13. Chapter 14. Carbohydrate Metabolism: . Glycolysis, Gluconeogenesis & the Pentose phosphate pathway. Carbohydrate Metabolism. Fates of Glucose. M. . Asal. Bsc. . Pharmacy. MSC ,PhD Clinical . Biochemistry. GLYCOLYSIS. REACTIONS . OF GLYCOLYSIS . The conversion of glucose to pyruvate occurs in two stages . ,The . first five reactions of glycolysis correspond to an energy investment phase in which the phosphorylated forms of intermediates are . Glycolysis & Gluconeogenesis. Glycolysis and Catabolism. Glycolysis is a sequence of enzyme-catalyzed reaction by which . glucose. is converted . into pyruvate. Pyruvate can be further aerobically oxidized. Dr.. Madhu Kumari Gupta. Assistant . Professor. Dept. of Chemistry. MMC, PU. Greek word- . glycos. meaning sweet/sugar and lysis meaning dissolution. Glycolysis is the first step in the breakdown of glucose to extract energy for cellular metabolism. Glycolysis consists of an energy-requiring phase followed by an energy-releasing phase.. Glycolysis occurs in ten steps , and in two phases :-. The first 5 steps constitute the PREPARATORY PHASE in which the energy of 2 ATP is invested, raising the free-energy content of the intermediates and the carbon chains of all the metabolized hexoses are converted into a common product glyceraldehyde-3-phosphate. . 1. FORWARD REACTION. REVERSE REACTION. D. G. o . (kJ). K. Significance. 200. 100. 50. 10. 1. 0. -1. -10. -50. -100. -200. 9x10. -36. 3x10. -18. 2x10. -9. 2x10. -2. 7x10. -1. 1. 1.5. 5x10. 1. 6x10. 8. Learning Goal . Describe how glucose is synthesized from . noncarbohydrate. molecules.. Glucose is synthesized in the tissues of the liver and kidneys. . Tissues . that use glucose as their main energy source are the brain, skeletal muscles, and red blood cells..

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