PPT-Unveiling virus-host interactions of marine protists through Single-Cell Genomics

Xabier LópezAlforja 1 David LópezEscardó 1 Manuel Martínez García 2 Sheree Yau 3 Ramon Massana 1 Felipe H Coutinho 1 amp Dolors Vaqué 1   DB nº query scaffolds . Parasitic Worms. Kingdom . Animalia. : . eukaryotic. , no cell walls, heterotrophic nutrition, specialized tissues. A. Platyhelminthes. Flatworms. e.g. planarians . Platyhelminthes. Trematoda. = flukes . Virology. Biology 516 Fall. Virology. Virology: is . the study of . viruses. . M. icroscopic. , parasitic particles of genetic material contained in a protein . coat.. Viruses . must. be within a host cell to reproduce.. July 22, 2013 8. th. Grade. Microbiology. the study of microscopic organisms, either . unicellular, multicellular.  (cell colony), or . acellular. Includes the disciplines virology, mycology, parasitology, bacteriology, and so on. P. . Lobosco. Monday November 8, 2010. There will be no grades given out until this Friday. Please do not ask!. HW-Read 11-1 and do the section review on page 273, questions 1-10 due Wed. Use spiral notebook.. Matt Resnick, Riley . Fosnot. , Adam Fields, Brandon Archibald. Overview. What is a Virus?. A microscopic. , . nonliving. particle that survives off of . host-cells. Simple structure made up of proteins and genetic material. Overview and Capabilities: . . High Throughput Sequencing Facility (HTSG). Functional Genomics M. ammalian Genotyping Core (MGC). Corbin Jones. Faculty Director. Piotr . Meiczkowski . Technologies . Viruses are not alive. A virus in an obligate intracellular parasite. Requires host cell to reproduce. Can be seen at magnifications provided by the electron microscope (they are microscopic). Characteristics of Viruses. Outcomes of the virus infection for the host . In the previous few chapters we have looked at . aspects of . the virus replication cycle that culminate in . the exit . of infective progeny . virions. Cell Structure & Function. Housekeeping…. WELCOME!!!! . NO EATING OR DRINKING ALLOWED IN THE AUDITORIUM. Put away your phones and any other distractions. Have handy a pen & a highlighter. Characteristics of Life. . Almaziny. Virology . Without a host cell, viruses cannot carry out . their . life-sustaining functions or reproduce. . Because : . They . cannot . synthesize proteins. , because they . Viruses are very small – smaller than the smallest cell.. They are usually surrounded by a capsid of proteins.. For replication, viruses rely on their host cells . ie. ., the cells they infect.. Most viruses exhibit a limited host range- they typically infect only specific types of cells of one host species.. MiSeq. (Illumina). 15 - 25 M short-reads. per sequencing run. Our Sequencers:. MiSeq. (Illumina). NextSeq. 2000 (Illumina). 400 - 1000 M short-reads. per sequencing run. Our Sequencers:. MiSeq. (Illumina). functions of archaebacteria, monerans. (eubacteria), protists, fungi, plants, and animals. including humans. . Key concepts include:. how their structures and functions vary between and within the kingdoms;. Host has elaborate systems to shut down viral functions. . The outcome of infection may vary from essentially benign and undetectable, to tolerated, to lethal.. Physiologic, immune, or inflammatory responses of the host.