PPT-Unveiling virus-host interactions of marine protists through Single-Cell Genomics

Xabier LópezAlforja 1 David LópezEscardó 1 Manuel Martínez García 2 Sheree Yau 3 Ramon Massana 1 Felipe H Coutinho 1 amp Dolors Vaqué 1   DB nº query scaffolds . analyze . your data with a mouse click. Igor Makunin. i.makunin@uq.edu.au. QAAFI, UQ, April 8, 2015. Research. Computing. Centre. @ UQ. Genomics Virtual Laboratory. Genome scale experiments are relatively cheap and very popular. Protists are a range of organisms that have many different features. This makes them really hard to classify.. Protists. While protists range significantly they do share common characteristics:. Most are unicellular. Instructions. You may use your notes.. Write your answers in the spaces provided.. This review is due at the end of the period!. 1. What . process is . shown in . the . diagram below. ?. . Describe what is happening in each step.. What Are Protists?. A group of one-celled organisms with well defined nuclei. All protists live in moist surroundings. Many protists possess both plant-like and animal-like features. Animal like protists are called PROTOZOAN . ). Protists. are….. organisms that cannot be classified into any other group (plant, animal, fungus, bacteria). o. rganisms that are typically made up of just one cell. o. rganisms that can be made up of many cells. selection, . regulation, epigenomics, . disease. Manolis Kellis. MIT Computer Science & Artificial Intelligence Laboratory. Broad Institute of MIT and Harvard. Goal: A systems-level understanding of genomes and gene regulation:. Overview and Capabilities: . . High Throughput Sequencing Facility (HTSG). Functional Genomics M. ammalian Genotyping Core (MGC). Corbin Jones. Faculty Director. Piotr . Meiczkowski . Technologies . Alan . Christoffels. South African Medical Research Council Bioinformatics Unit, South African National Bioinformatics Institute, University of the Western Cape, South Africa, Secretariat: Public Health Alliance for Genomic Epidemiology. Federoff. Bacterial Diseases. Microorganisms—viruses and prokaryotes—that cause disease are called . pathogens. . Louis Pasteur helped to establish what has become known as the . germ theory of disease . Viruses are very small – smaller than the smallest cell.. They are usually surrounded by a capsid of proteins.. For replication, viruses rely on their host cells . ie. ., the cells they infect.. Most viruses exhibit a limited host range- they typically infect only specific types of cells of one host species.. What . is . Functional. . Genomics?. RNA . Transcription/Gene. . Expression. Measuring Gene. . Expression. Microarrays. High-throughput. . Sequencing. Transcriptional. . Regulation. Transcription. FUNGi. Lesson 1. What are . Protists. ?. Protists. share characteristics with:. Plants. Animals. Fungi. But they don’t fit into any of those kingdoms!. A . protist. is a member of a group of eukaryotic organisms, which have a membrane-bound nucleus. MiSeq. (Illumina). 15 - 25 M short-reads. per sequencing run. Our Sequencers:. MiSeq. (Illumina). NextSeq. 2000 (Illumina). 400 - 1000 M short-reads. per sequencing run. Our Sequencers:. MiSeq. (Illumina). Host has elaborate systems to shut down viral functions. . The outcome of infection may vary from essentially benign and undetectable, to tolerated, to lethal.. Physiologic, immune, or inflammatory responses of the host.