PPT-Lecture 4: Molecular Mechanisms of Gene Regulation

Chapter 9 Presented by Dr Laurie M Erickson Chair of the Department of Health Sciences Blitstein Institute of Hebrew Theological College Chicago IL USA Gene Expression can be Regulated Gene expression . . University of Kentucky: . Andrew . Bouwma. Peter . Mirabito. Jeffrey Osborn. . Stanford University:. Shyamala Malladi. Patricia Seawell. University of Miami:. Douglas L. Crawford. Marjorie F. Oleksiak. . 19. . –. . Epigenomics. – Plants. . BIOL 5190/6190 Cellular & Molecular . Singal. Transduction. Prepared by Bob Locy. Last modified -13F. Epigenetics. – . Stable, but expression-related changes in gene function. Eukaryotic Gene Regulation. How are genes turned on & off . in eukaryotes?. How do cells with the same genes differentiate to perform completely different, specialized functions?. Evolution of gene regulation. Title of teachable tidbit: “Biomedical Applications of Gene Dosage Compensation”. General Topic:. Molecular. Gene Regulation. Two sentence. synopsis . of tidbit:. Tidbit. focuses on teaching gene dosage compensation to students and having them apply this knowledge to address a biomedical issue . A. W. Schreiber. Australian Centre for Plant Functional Genomics. Waite Campus, . University of Adelaide. Achievements and new directions. in Subatomic Physics:. Workshop in Honour of Tony . Thomas’s 60. Gene Expression Group. 7/14/11. 2011 National Academies Northstar Institute for Undergraduate Education in Biology . Outline. Context. Review: Clicker Questions. Cell Differences (Think-Pair-Share). Regulation of Gene Expression (Mini-Lecture). Pre-transcriptional regulation. chromatin compaction . eg. . deacetylation. , . methylation. transcriptional initiation . ie. transcription factors to activate or repress. alternative promoters =. Outline. Objective. Mechanism. K. inase cascades and Phosphorylation/. dephosphorylation. . General. Learning/LTP. Synaptic strengthening. Control of gene expression. Transcription factors. Epigenetics. CSCOPE. Unit: 08 Lesson: 01. There are hundreds of different types of cells in your body, and each type has a unique function. We’re going to compare some different types of cells to see how much they have in common. . Son Dong, Justin Wise, Niket Yadav. . History. Confusing disease . in mid . 1. 6. 00s. Had different names based on symptoms. First mention was in 1842. Major discoveries occurred . after:. Charles Gorman, Johan Lund. Draw 8 boxes on your paper. Gene regulation accounts for some of the phenotypic differences between organisms with similar genes.. 2005-2006. Gene regulation in bacteria. Control of gene expression enables individual bacteria to adjust their metabolism to environmental change. Asst. Prof. Dr. . Dalya. Basil Hanna . In this lecture…... Mutation:. Gene (point) Mutation. Chromosomal Mutation. Gene Mutation . A gene mutation occurs when the nucleotide sequence of the DNA is altered and a new sequence is passed on to the offspring. The change may be either a substitution of one or a few nucleotides for others or an insertion or deletion of one or a few pairs of nucleotides. Dr. Mamoun Ahram. Faculty of Medicine. Second year, Second semester, 2014-2014. Structure and function of a nucleus. A repository of genetic information. The nuclear membrane, known as the nuclear envelope, adds an additional level of gene regulation post-. AP Bio – Ch. 16-21. Unit 6 – Overview. Ch. 16 – The Molecular Basis of Inheritance (DNA). Ch. 17 – Gene Expression: From Gene to Protein. Ch. 18 – Regulation of Gene Expression. Ch. . 19 . – .