PPT-Designing vaccines against visceral leishmaniasis: Importan

liposomes Prof Nahid Ali CSIRIndian Institute of Chemical Biology 4 Raja SC Mullick Road Kolkata 700032 Caused by Leishmania donovani and L infantum Approximately 300 000 new visceral cases occur annually 90 in Bangladesh Brazil Ethiopia India Nepal South Sudan and Sudan. Sreenivas Poonam Salotra Hira L Nakhasi Division of Emerging Transfusion Transmitted Diseases Office of Blood Research Review Center for Biologics Research Review US Food Drug Administration Bethesda USA Institute of Pathology Safdarjung Hospi presented by. Dr . Hadeel. F. Gad. Leishmania . and Mycobacterium TB share many similarities in their pathogenesis and both pathogens are macrophage parasites. . Furthermore, . co-infection by the two pathogens is not uncommon in clinical practice in East Africa and in other parts of the world (Sati 1942; el-Safi et al. 1995; Khalil et al. 1998, . Leishmaniasis.  . By. Tarik. . Zaher. ,MD. Assistant Professor of Endemic and Tropical Medicine ,. Zagazig. University. Background. Leishmaniasis. is a . protozoal. disease capable of causing a spectrum of clinical syndromes ranging from . presented by. Dr . Hadeel. F. Gad. Leishmania . and Mycobacterium TB share many similarities in their pathogenesis and both pathogens are macrophage parasites. . Furthermore, . co-infection by the two pathogens is not uncommon in clinical practice in East Africa and in other parts of the world (Sati 1942; el-Safi et al. 1995; Khalil et al. 1998, . presented by. Dr . Hadeel. F. Gad. Leishmania . and Mycobacterium TB share many similarities in their pathogenesis and both pathogens are macrophage parasites. . Furthermore, . co-infection by the two pathogens is not uncommon in clinical practice in East Africa and in other parts of the world (Sati 1942; el-Safi et al. 1995; Khalil et al. 1998, . Tel.: +91-0612-2221797, Fax:+91-0612-2239423 “History of kala-azar is older than the dated • Leishmaniasis• Internal leishmaniasis• Visceral • General • Kala-azar of
. Suhad Faisal . Hatem. . Flagellate of blood and tissue . This parasite include two genus . Leishmania. spp. . . and. . Trypansoma. spp. .. They are pathogenic to man and may exist in two or more form in life cycle (. The promastigote stage (long, slender form with a free flagellum) is present in the saliva of infected sandflies. Human infection is initiated by the bite of an infected sandfly, which injects the promastigotes into the skin, where they lose their . 1900 – . Sir William. . Leishman. discovered. L. . donovani. in spleen. smears of a soldier. who died of fever at. Dum-Dum, India.. The disease was. known locally as. Dum-Dum fever or. Dr.Shaymaa. Abdalal. Demonstrator in Medical Parasitology Department . The Parasite. Phylum. Order. Family. Genus. Sarcomastigophora. Kinetoplastida. Trypanosomatidae. Leishmania. Leishmaniasis. Disease. Clinical Phenotypes. Cutaneous . Leishamaniasis. Mucocutaneous. . Leishmaniasis. Visceral . Leishmaniasis. Post Kala-azar dermal . leishmaniasis. Phenotypes . o. f the . Leishmaniases. VISCERAL LEISHMANIASIS. .. Cintya Perdomo . a. , Elena Aguilera . b. , Ileana Corvo. a. , Paula . Faral. -Tello . c. , Elva Serna . d. , Carlos . Robello. . c, e. , . Shane. R. . Wilkinson. f. , Gloria Yaluff . d. , . Guzmán . Bhattarai NR, Van der Auwera G, Rijal S, Picado A, Speybroeck N, Khanal B, et al. Domestic Animals and Epidemiology of Visceral Leishmaniasis, Nepal. Emerg Infect Dis. 2010;16(2):231-237. https://doi.org/10.3201/eid1602.090623. A. mastigote . Pro. mastigote. . Epi. mastigote. . Trypo. mastigote. . Eccentric nucleus. . Central nucleus. Free Flagellum . Free Flagellum. . Free Flagellum. . No free flagellum. Central nucleus.