PPT-Genome Analysis of

L donovani revealing the correlation of its pathogenesis and speciesspecific genes Presented by Dr Monidipa Ghosh Assistant Professor Department of Biotechnology NIT Durgapur. Denovo genome Denovo genome outline outline novogenome from contigs from assembled contigs annotation Denovo genome Denovo genome Reads contig Gene Gene Annotation Gene Annotation Forgene sequencing . for . identification,. detection, . and control of . Bactrocera dorsalis (. Hendel. ). and other Tephritid pests. Thomas Walk, Scott . Geib. USDA-ARS Pacific Basin Agricultural Research Center, Hilo HI. Jeroen. . Raes. , Jan O . Korbel. , Martin J . Lercher. , Christian von . Mering. and Peer Bork. Presented by Daehwan Kim. Outline. Genome size. Genome sizes of Archaea, Bacteria, and Eukaryotes. Factors affecting genome and genome sizes . Mayo/UIUC Summer . C. ourse in Computational Biology. Session Outline. Genome sequencing. Schematic overview of genome assembly. (a) DNA is collected from the biological sample and sequenced. (b) The output from the sequencer consists of many billions of short, unordered DNA fragments from random positions in the genome. (c) The short fragments are compared with each other to discover how they overlap. (d) The overlap relationships are captured in a large assembly graph shown as nodes representing . Genome Browser. Combines a genome database with interactive web pages. Allows the user to retrieve and manipulate database record through a graphical user interface (GUI). Different types of information are displayed in an intuitive fashion in user-configurable “tracks”. Mayo/UIUC Summer . C. ourse in Computational Biology. Session Outline. Genome sequencing. Schematic overview of genome assembly. (a) DNA is collected from the biological sample and sequenced. (b) The output from the sequencer consists of many billions of short, unordered DNA fragments from random positions in the genome. (c) The short fragments are compared with each other to discover how they overlap. (d) The overlap relationships are captured in a large assembly graph shown as nodes representing . hypoxic inflammatory environment. Mahmood. Bhutta. TWJ & . Colledge. . Family . Memorial Otology Fellow. University . of Western Australia. Royal Perth . Hospital. James . Ramsden. Steve Brown. Genome: the total number of genes in an individual.. Human Genome- approx. 20,000 genes on the 46 human chromosomes.. Human Genome Project (HGP). Ongoing effort to completely map and sequence our genome.. Nadia Khan, Rick Smith, . and Anna . Kuperman. Epigenetics 2012. Introduction. Most Genome Wide Approaches were adapted from technologies originally developed for detecting methylation at the level of a single gene. Isabella. Roland. Sarahi. Veronica. General protocol. Isolation of . vibrios. . DNA extraction. Illumina. sequencing. Assembly and annotation. Quality of data.  . Year . HS0A . 2012. HS0B . 2012. HS0C . Kesheng Wang, PhD. Department of Biostatistics and Epidemiology. College of Public Health. East Tennessee State University. 2. Outline. Introduction . Alcohol dependence (AD). Genetic study. . Subjects and Methods. Loren Hauser. Miriam Land. Yun-Juan Chang. Frank Larimer. Doug Hyatt. Cynthia Jeffries. NEB Educational Support. 2. http://www.neb.com/nebecomm/course_support.asp?. Why study Computational Biology. . Benjamin Neale, PhD. Boulder Workshop. Content warning: eugenicists. Sick individuals and sick populations Rose 1985. Mendelian. Genetics. Co-dominance. East 1915: Inheritance of Corolla Length in . emm1. invasive Group A . Streptococcus. isolated from Belgian patients during 1994˗2013 . J. Coppens. 1. , . B. B. . Xavier,. . J. Sabirova. 1. , C. Lammens. 1. , K. Loens. 2. , S. Malhotra-Kumar.