PPT-The Use of Shikonin to Reduce Viability of Breast Cancer Cell Lines T47D and MDA-MB-231

Alexis Clark 1 and Rebecca Haberman 1 1 Dept of Biology Mary Baldwin University Staunton VA Introduction In the United States alone 1 in 8 women will develop invasive breast cancer over the course of their lifetime1. Cell . Viability. In biological systems, viability often refers to an ability to maintain homeostasis. Plasma membrane integrity, DNA synthesis, DNA content, enzyme activity, presence of ATP, and cellular reducing conditions are known indicators of cell viability and cell death.. Friends of Brownhill Surgery. Patient Participation Group. There are over 200 types of cancer.. One in three people will develop a cancer during their lifetime.. The risk of developing cancer increases with age.. Jennifer M. Matro, MD. Rena Rowan Breast Center. Abramson Cancer Center. University of Pennsylvania. Overview. What is metastatic breast . c. ancer (MBC)?. Who is at risk?. Subtypes of Breast Cancer. with. . 99m. Tc Labeled. Methotrexate Loaded Chitosan Nanoparticles. for Breast Cancer Diagnosis. Meliha Ekinci, . MSc. Pharm. . Ege University, Faculty of Pharmacy. Department of . Radiopharmacy. 35100 Bornova, . Exploring “Cell Signaling”. Carol A. Lange, PhD. Professor of Medicine and Pharmacology. Tickle Family Land Grant Endowed Chair of Breast Cancer Research. Lead: Masonic Cancer Center Cell Signaling Program. Susan Hingle, MD, FACP. Professor of Medicine. Division of General Internal Medicine. Interim Chair. SIU School of Medicine. Session Objectives. Identify the cancers in which aspirin therapy may play a role in prevention.. Matthew Beatty, Brynn Cullander, Melissa Frank, Justin Ludwig, Mosharaf Mahmud Syed, Andrew Pierce, and Ashton Sigler. History. Discovered in the 1984 by Roel Nusse and Harold Varmus as the int1 gene.. Julie R. Gralow, M.D.. Director, Breast Medical Oncology. Jill Bennett Endowed Professor of Breast Cancer. Professor, Global Health. University of Washington School of Medicine. Fred Hutchinson Cancer Research Center. QSOX1. P4HB. BGN. EIF4A1. SEC23A. IPO5. KLK3. CD9. RPS20. TGFBI. AGRN. CTSD. NME2. B2M. SF1. SDCBP. ANXA2. IGFBP4. NPC2. ITSN1. CYR61. DCN. PPIB. HNRNPK. ATP6AP1. GAPDHS. PSAP. PTPRG. YWHAG. IGFBP7. NRP1. human lung healthy pleura MRC-5 . cell lines treated with novel bridged . heteronuclear. Zn(II)-L-Cu(II) . Asija Halilagić. 1. , Tanja . Soldatović . 1. ,. *, Enisa Selimović . 1. , . Nevena Milivojević . of genomic profiles. Domcke. , S. et al. . Nat. . . Commun. . 4. :. 2126. Motivation. Problem: Genomic differences between cancer cell lines and tissue samples. TCGA and CCLE provide molecular profiles for tumor samples and cell lines. 294 Human Breast Cancer Cell Line Copy Right@ Sen Pathak This work is licensed under Creative Commons Attribution 4.0 License AJBSR.MS.ID.001996. American Journal of Biomedical Science & Research ww 20 1 1 , 2 http://www. jcancer .org 186 J J o o u u r r n n a a l l o o f f C C a a n n c c e e r r 20 1 1 ; 2 : 1 86 - 192 Case Study Infiltrating Ductal Carcinoma of the Breast Associated with Pri Table 1: Breast Cancer Cell Lines. . Changes in the total amount of hormone receptors will be determined by Western blotting. We expect that HCMV infection will reduce the expression of hormone receptors and decrease the cells’ responsiveness to extracellular stimuli..