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AND AUTOIMMUNE DISEASES RAKESH SHARDA Department of Veterinary Microbiology NDVSU College of Veterinary Science AH MHOW Spleen Lymph Nodes Thymus Bone Marrow T cell Development In normal i. Chris Lancaster, Emily Mathews, Jake Turner . Questions:. c.j.lancaster@warwick.ac.uk . Jake.Turner@warwick.ac.uk. E.K.Mathews@warwick.ac.uk. Definitions . Immunological . Tolerance:. Unresponsiveness . Auto. i. mmune . Disease Ontology. Alexander D. Diehl. 6/13/12. Neurological Disease Ontology (ND). Based on the Ontology for General Medical Sciences. Incorporates parts of NIF-Dysfunction. Three initial . Department of Rheumatology. University of Stellenbosch. Immunology. Innate and adaptive immunity: cells. Innate and adaptive immunity. MHC class I and II. Complement system. Activation of innate immunity. , Antiphospholipid. . Syndrome and Systemic Lupus Erythematosus). Sandeep . Singh, . MD, Shoaib Junejo, MD, Adriana Abrudescu, MD, FACR. ,. . Isaac Sachmechi, MD, FACE, FACP.. Department of Medicine/Rheumatology/Endocrinology Icahn School Of Medicine at Mount . AUTOIMMUNE DISEASES. AUTOIMMUNITY. The . term autoimmunity refers to a failure of the body’s immune system to recognize its own cells and tissues as “self”, Instead immune responses are launched against these cells and tissues as if they were foreign or invading bodies. immunopathology. concerns disorders caused by alterations of the immune response. 3 main categories of alterations:. . excessive response hypersensitivity reactions. inappropriate . . response . Tomas Milota, MD.. Department . of. . Immunology. ,. Department . of. . Rheumatology. ,. Second . Medical. . Faculty. , Charles University . and Motol University . Hospital. , Prague. Basic . characteristics. . immunological tolerance. Immunological . tolerance is a state of unresponsiveness to a particular antigen to which a person has been exposed earlier. .. . . The important aspect of tolerance is the self-tolerance, which prevents the body to mount immune response against self-antigens. Antibody- B cell checkpoints in autoimmune SamuelJ.S.Rubin, MichelleS.Bloom and WilliamH.RobinsonAbstract B cells have important functions in the pathogenesis of autoimmune diseases, including REVIEW Autoimmune diseases affect about 5% of individuals inAlthough the prevalence of mostincidence has greatly increased over the past few years, asgroups that are often selected as targets for vacc LECTURE : 07 LEARNING OBJECTIVES : The student should be able to: Describe the term "autoimmune", indicate if it is either Define the term "autoantibodies". Determine if the autoantibodies eit Autoimmunity March 2016 What is autoimmunity? In healthy individuals the immune system constantly protects us from the native and foreign microorganisms – such as viruses, bacteria, and parasit �
���������� � �� �� ������ ����& Autoimmunity. is the system of immune responses of an organism against its own cells and tissues. Any disease that results from such an aberrant immune response is termed an autoimmune disease.. These .