PPT-Autoimmunity Autoimmunity

Autoimmunity is the system of immune responses of an organism against its own cells and tissues Any disease that results from such an aberrant immune response is termed an autoimmune disease These . Department of Rheumatology. University of Stellenbosch. Immunology. Innate and adaptive immunity: cells. Innate and adaptive immunity. MHC class I and II. Complement system. Activation of innate immunity. Mark S. Anderson, MD, PhD. UCSF. Disclosures. Research support from Juno Therapeutics. Consultant for . Sanofi. 2. 3. Lecture outline. Principles of immune regulation . Self-tolerance; mechanisms of central and peripheral . , Antiphospholipid. . Syndrome and Systemic Lupus Erythematosus). Sandeep . Singh, . MD, Shoaib Junejo, MD, Adriana Abrudescu, MD, FACR. ,. . Isaac Sachmechi, MD, FACE, FACP.. Department of Medicine/Rheumatology/Endocrinology Icahn School Of Medicine at Mount . Anna Postolova, MD MPH. Allergy/Immunology/Rheumatology. Menlo Medical Clinic. Stanford Health Care . Disclosures . Nothing to disclose. Objectives. Recognize aspects of history and presentation that are suggestive of a primary immunodeficiency or immune dysregulatory syndrome in rheumatology patients. Assistant Professor. Department of Microbiology. AIIMS, Rishikesh. Learning objectives. By the end of this session student should be able to understand:. Central and peripheral tolerance. Theories of autoimmunity. AUTOIMMUNE DISEASES. AUTOIMMUNITY. The . term autoimmunity refers to a failure of the body’s immune system to recognize its own cells and tissues as “self”, Instead immune responses are launched against these cells and tissues as if they were foreign or invading bodies. By: . Dr Puneet Kumar Gupta . Assistant Professor, Microbiology. 1. 2. 3. 4. 5. 6. 7. 8. Tolerance and Autoimmunity. 9. What is tolerance?. Mechanisms to protect from potentially self reacting lymphocytes. . immunopathology. concerns disorders caused by alterations of the immune response. 3 main categories of alterations:. . excessive response hypersensitivity reactions. inappropriate . . response . Antibody- B cell checkpoints in autoimmune SamuelJ.S.Rubin, MichelleS.Bloom and WilliamH.RobinsonAbstract B cells have important functions in the pathogenesis of autoimmune diseases, including REVIEW Autoimmune diseases affect about 5% of individuals inAlthough the prevalence of mostincidence has greatly increased over the past few years, asgroups that are often selected as targets for vacc LECTURE : 07 LEARNING OBJECTIVES : The student should be able to: Describe the term "autoimmune", indicate if it is either Define the term "autoantibodies". Determine if the autoantibodies eit Autoimmunity March 2016 What is autoimmunity? In healthy individuals the immune system constantly protects us from the native and foreign microorganisms – such as viruses, bacteria, and parasit �
���������� � �� �� ������ ����& Marian . Rewers, MD, PhD. Sponsors:. Patten-Davis Foundation. Autoimmunity Screening for Kids (ASK), 2017-2022 . Screened >30,000 Colorado general population children 1-17 y old. Prevalence of pre-symptomatic T1D - 1.0% (95%CI –0.9- 1.1%).