PPT-Polymeric biomaterials for engineering antigen specific immune responses

Won Seok Song 1 Scott Wilson 2 1 Johns Hopkins University Department of Materials Science and Engineering 2 Johns Hopkins Medical Institutions Introduction Reaction Schema Conclusion. Cell and its Role in Adaptive Immunity and Cancer Immunotherapy. Amna. Muhammad. Ph. D scholar. Biochemistry. 1. Contents. Introduction. Dentritic cell and control of immunity. Immunity. Antigen Presentation to T cells. The Body’s Defenses. Nonspecific Defenses Against Infection. The skin and mucous membranes provide first-line barriers to infection. -skin prevents the entry of pathogens. - mucous membranes line digestive and respiratory tracts. Types of Antigen. Complete Antigen: Substances which can induce antibody formation by themselves. . Haptens: substances which are unable to induce antibody formation on its own but can become immunogenic, i.e., capable of inducing antibodies, when covalently linked to proteins known as carrier proteins.. Non-specific Immunity. Born with some immunity . Helps prevent disease. Helps slow disease progression. First line of defense. Non-specific, cont. .. Physical Barrier- . unbroken skin . Non-specific Immunity. Born with some immunity . Helps prevent disease. Helps slow disease progression. First line of defense. Non-specific, cont. .. Physical Barrier- . unbroken skin . Kuby. . Immunology. , . 7e: Chapter 1. A historical perspective of immunology. What is immunity?. Immunity is the state of protection against foreign pathogens or substances (antigens). Latin term . Plants and animals have a variety of chemical defenses against infections that affect dynamic homeostasis.. Fig. 43-2. INNATE IMMUNITY. Recognition of traits. shared by broad ranges. of pathogens, using a. Immune Responses. Applications of the Immune Response. A. Vaccination – the practice of deliberately stimulating the immune system in order to protect individuals against a disease. 1. Edward Jenner developed the first official smallpox . Overview of the Immune System. A historical perspective of immunology. What is immunity?. Immunity is the state of protection against foreign pathogens or substances (antigens). Latin term . immunis. Dr. . Amany. . Ballow. . Consultant Immunology . Assistant professor KKUH. General Lab Director MDLAB. PhD, Diploma BSHI,MSC.. Objectives . To describe B-cells as the mediators of humoral immunity, (antibody-mediated immunity). Organs and . cells. Peter Kelleher. Senior Lecturer, Imperial . College London, . Chelsea & Westminster . campus. Learning objectives . Illustrate the importance of immunology for human health..  . B. Antigen (Ag). A substance that reacts with the products of a specific immune response.. C. Hapten. A substance that is non-immunogenic but which can react with the products of a specific immune response.. Adaptive . Non-adaptive (. cell injury-----cell death). hypertrophy. Dysplasia. hyperplasia. neoplasia. Atrophy. Degeneration. Metaplasia. Necrosis, apoptosis. & gangrene. Reversible. Reversible* / Irreversible. Dr. Ahmed Ali Mohammed. Immunology. : . is the science that studying our protection from foreign macromolecules or invading organisms and our responses to them. These invaders include viruses, bacteria, protozoa or even larger parasites..