PPT-Polymeric biomaterials for engineering antigen specific immune responses

Won Seok Song 1 Scott Wilson 2 1 Johns Hopkins University Department of Materials Science and Engineering 2 Johns Hopkins Medical Institutions Introduction Reaction Schema Conclusion. Oral immunity and . immunopathological. processes in the mouth.  Immunity. Microorganisms are in the air we breathe and in/on the food we eat;. Thus our epithelial surfaces are continuously exposed to microorganisms;. Oral immunity and . immunopathological. processes in the mouth.  Immunity. Microorganisms are in the air we breathe and in/on the food we eat;. Thus our epithelial surfaces are continuously exposed to microorganisms;. Non-specific Immunity. Born with some immunity . Helps prevent disease. Helps slow disease progression. First line of defense. Non-specific, cont. .. Physical Barrier- . unbroken skin . Kuby. . Immunology. , . 7e: Chapter 1. A historical perspective of immunology. What is immunity?. Immunity is the state of protection against foreign pathogens or substances (antigens). Latin term . Abul K. Abbas. UCSF. FOCiS. 2. Lecture outline. Self-tolerance; central and peripheral tolerance. Inhibitory receptors of T cells . Regulatory T cells . 3. Immunological tolerance. Definition:. . unresponsiveness to an antigen induced by exposure of lymphocytes to that antigen; antigen-specific (unlike “immunosuppression”). Dr Rehma Dar. Assistant professor Pathology. Introduction to Immune System. Cell mediated vs Humoral Immunity. Hypersensitivity reactions. Autoimmune diseases. Transplant Rejection. Immunodeficiency states. Immune Responses. Applications of the Immune Response. A. Vaccination – the practice of deliberately stimulating the immune system in order to protect individuals against a disease. 1. Edward Jenner developed the first official smallpox . Dr. Suzan Y.. Antigen. :. It s a substance that may be specifically bound by an antibody (. Ab. ) molecule or T cell receptors (TCR). When this binding lead to the activation of B cells or T cells ,this substance is known as . Overview of the Immune System. A historical perspective of immunology. What is immunity?. Immunity is the state of protection against foreign pathogens or substances (antigens). Latin term . immunis. Martin Liška. 1. The structure of immunoglobulins. 2. Isotypes. (in principle) classes of antibodies distinguished on the basis of H chain structure differences. 5 types: . m. (IgM), . d. (IgD), . Dr. Refif S. Al-. Shawk. . Lec. 3. 2021-2022. Parasitic Infections. The term parasite encompasses a vast array of infectious protozoans (unicellular) and metazoans (helminths or worms). . Protozoan. Assist. Professor . Dr. Sinan Bahjat. M.B.Ch.B., M.Sc., F.I.B.M.S. . Antigens . are . molecules that react with antibodies. , . whereas immunogens . are . molecules . that induce an . immune response. By: . . . Dr. Murtaza Najabat Ali . (CEng MIMechE P.E.). 1. Definitions. . Biomaterial. . - . . “. is any synthetic material that is used to replace or restore function to a body tissue . Adaptive . Non-adaptive (. cell injury-----cell death). hypertrophy. Dysplasia. hyperplasia. neoplasia. Atrophy. Degeneration. Metaplasia. Necrosis, apoptosis. & gangrene. Reversible. Reversible* / Irreversible.