PPT-Emphysema: It is characterized by loss of lung elasticity and abnormal enlargement of

Two of the recognized causes of emphysema are smoking which incites lung injury and inherited deficiency of α1 antitrypsin an antiprotease enzyme that protects the lung from injury Emphysema is thought to result from the breakdown of . By: Jessica S., Forster A., and Zach D.. Definition. A long term, progressive disease of the lungs that primarily causes shortness of breath. In people with emphysema, the tissues necessary to support the physical shape and function of the lungs are destroyed. It is often caused by smoking. . Robert Padera, M.D., Ph.D.. HBTM. 235. September 21, 2015. rpadera@partners.org. Goals. To teach you everything something about respiratory physiology and pathology. To set the stage for lecture on lung transplantation. (. kwaf. ) v. . to drink heartily . I offered her a sip, but she . QUAFFED . my entire soda. . Fraternity . parties often involve the . QUAFFING . of large quantities of beverages. . Many . of the senior citizens were guilty of . Prof. Khaled KARARA. Prof. . . of Department of Cardiothoracic Surgery. Alexandria Faculty of Medicine. Emphysema. Emphysema, along with chronic bronchitis, together are referred to as . Chronic Obstructive Lung Disease (COPD).. . . ystic. . Fibrosis. . . ronchitis. . – Chronic. . sthma. . . . ronchiectasis. . . mphysema. Chronic . Obstructive Pulmonary Disease. Smoking. #1 cause of COPD. Increased mucous production. Maram. . abdaljaleel. , MD. Dermatopathologist. &. neuropathologist. It’s hard to get the air OUT. It’s hard to EXHALE. Lungs are . hyperinflatted. EMPHYSEMA. CHRONIC BRONCHITIS. ASTHMA. BRONCHIECTASIS. What is COPD?. How to treat COPD?. What is the prognosis?. 19.3% of US Adults Smoke – 2010. CDC, NHIS 2010. 2010 Current Smokers. %. of Smokers. Demographic. % of Smokers. Demographic. 19.3%. US Adults. F. unction. The MESA Lung Study. R Graham Barr, MD . DrPH. Departments of Medicine and Epidemiology. Columbia University Medical Center. Funding: NHLBI . R01s HL077612. ,. HL075476. ,. HL093081. RC1 . Dani. S. . Zander. , MD. Professor and Chair, Dept. of Pathology. Penn State College of Medicine/Penn State M.S. Hershey Medical Center, Hershey, PA. Smoking-Related Lung Diseases. Cause. Chronic obstructive lung disease (COPD): emphysema, chronic bronchitis, small airway disease. Clinical Policy: Lung volume reduction by surgery or endobronchial valve for severe emphysema in adults NHS England Reference: 200806P [1622] V2.0 January 202 2 [First Published November 2020] 2 DOI:10.1183/09031936.94.07040664 EExtentfentrilobula M. Saetta*, W.D. Kim Extent of centrilobular and panacinar emphysema in smokers' lungs: pathological andmechanical implications. M. Saetta, W.D. K Definition: . Emphysema . is defined as a . pathological increase . in the size of airspaces distal to the . terminal bronchioles. , with destruction of the alveolar walls. . ETIOLOGY. Diseases . of the airways: Chronic bronchitis, . Shaesta. . Naseem. 10-2-13. Lung. Capillary lumen. Type I pneumocyte. Type I pneumocyte. Type II. pneumocyte. Endothelium. Alveolar space. The respiratory acinus. Cartilage is present to level of proximal bronchioles. R Graham Barr, MD . DrPH. Departments of Medicine and Epidemiology. Columbia University Medical Center. Funding: NHLBI . R01s HL077612. ,. HL075476. ,. HL093081. RC1 . HL100543. Remember Sept 18. th.