PPT-Mendelian Genetics

20152016 Ms McCabe standards SC912L161 Use Mendels laws of segregation and independent assortment to analyze patterns of inheritance SC912L162 Discuss observed inheritance patterns caused by various modes of inheritance including dominant recessive codominant sexlinked polygenic and multiple alleles. Mendelian. Genomics. www.mendelian.org. gmendel@mendelian.org. Goal: Identify and define the causes of all human . monogenic diseases. Explain human biology. Allow diagnostic testing important for disease prevention, therapy and prognosis. Review. ____________________ is the “Father of Genetics”.. Gregor. Mendel. _______________ is the passing of traits from parent to offspring.. Heredity. A _________ represents the physical characteristics.. David Evans. Some Criticisms of GWA Studies…. So you have a new GWAS hit for a disease… so what!?. You can’t change people’s genotypes (at least not yet). You can however modify people’s environments…. - genetic material on a chromosome that codes for a specific trait. Genotype. - the genetic makeup of the organism. Phenotype-. the expressed trait. Allel-. an alternative form of a gene. Genetic Definitions. David Evans. University of Queensland. University of Bristol. Some Criticisms of DOC Modelling in Twins. Measurement error. Power (both variables need to have radically different aetiologies). Only useful for testing strong hypotheses about causation. How are traits passed down from parents to offspring?. Concept 1. : Analyzing the effects of classic . Mendelian. genetic crosses such as . monohybrid, . dihybrid. , testcross. , and applying to . pedigree. Oregon State University. A . trait. is a measurable feature or behavior of an organism; it can have multiple . phenotypes. “attached” earlobe. “detached” earlobe. Some traits are more discrete, others continuous. Practice Problems. Question #1. In rock pocket mice, dark color is recessive to light . color. Write . the genotypes and phenotypes for the following . individuals:. Genotype. Phenotype. Heterozygous. Genes and Inheritance. 2017. ggibson.gt@gmail.com. http://www.cig.gatech.edu. Course Outline. 1. Genes and Inheritance (GG). 2. Molecular Biology of the Genome (JL). 3. . Population and Evolutionary Genetics (JL). Genetics. Genetics. is the study of inheritance of genes. . i.e. genetics is how traits are passed down from parents to offspring . Every individual offspring inherits at least two copies of every gene – one from the mother and one from the father. . Genomics Lesson 12_1. Ross . Hardison. 4/19/15. 1. Genetic association. The occurrence together in a population, more often than can be readily explained by chance, of two or more traits of which at least one is known to be genetic.. Gregor Mendel:. 1823-1884. 2. Genetics. Genetics. . is the Study of heredity (the transmission of traits from generation to generation).. . Genetics began with the work of . Gregor. Mendel. Mendel developed basic principals of heredity with . 1 Human Population Genetics Mendelian Inheritance in Man Paper No. : 0 8 Human Population Genetics Module : 0 6 Mendelian Inheritances in Man Prof. Anup Kumar K apoor multifactorial traits affected research into Mendelian disorders? Stylianos E. Antonarakis. For about a century, the argument for focusing on rare Mendelian disorders was as follows: Mendelian ph