PPT-Realized Genomic Relationships and Genomic BLUP

Fikret Isik Associate Professor September 16 2013 Genomic BLUP UofCopenhagen 1 Cooperative Tree Improvement Program North Carolina State University Raleigh USA Outline Background Realized genomic relationships. Early genomic theory. Nejati-Javaremi. et al (. 1997. ) tested use of genomic relationship matrix in BLUP. Meuwissen et al (. 2001. ) tested linear and nonlinear estimation of . haplotype. effects. Selection and Sustainable Cattle Production: Are the Incentives Aligned. ?. Ellen Goddard. Albert . Boaitey. , Anahita . Matin. , Violet . Muringai. , . Getu. . Hailu. (U. of Guelph). Canadian Cattle . Genotypes are Useful for More Than Genomic Evaluation Uses for genotypes Ancestor discovery within breeds Inheritance tracking for chromosomes Mating programs Genomic inbreeding, dominance Fertility defects – haplotypes and QTLs exposomic. findings to realize the precision medical care in Tohoku Medical Megabank. 0. Division of . Bioclinical. . Imformatics. Tohoku Medical Megabank Organization, . Tohoku University. Hiroshi Tanaka, . George Wiggans, CDCB Technical Advisor. Highlights of U.S. system. Over half a million animals genotyped in 2016. 67% of AI breedings to genomic bulls. Genomic relationship between genotyped cows and marketed bulls available. Dina Paltoo, Ph.D., M.P.H.. NIH Office of Science Policy. Laura Lyman Rodriguez, Ph.D.. National Human Genome Research Institute. October 4, 2017. Housekeeping. Participants must register to join the webinar. Dairy Cattle. 9 million cows in US. Attempt to have a calf born every year. Replaced after 2 or 3 years of milking. Bred via AI. Bull semen collected several times/week. Diluted and frozen. Popular bulls have 10,000+ progeny. Chuanyu Sun. 1. , Paul M. VanRaden. 2. , Jeff R. O'Connell. 3. 1 . National Association of Animal Breeders, USA, Columbia, MO;. 2 . Animal Improvement Programs Laboratory, Agricultural Research Service, USDA, Beltsville, MD, USA. . Rachel Butler, Head of Bristol Genetics Laboratory. National delivery of 100,000 . Genomes . P. roject. A remarkable achievement. Genomic Laboratory Hubs. South West Genomic Laboratory Hub (SWGLH). Partnership . post 100,000 . Genomes . Project. Update . – Haem SSG . Nov 2018. Contents. Genetics and genomics. Background to 100,000 Genomes Project. Project progress. What next? Mainstreaming Genomic Medicine. Laura Yarram-Smith. SWGLH Solid Tumour Laboratory Lead. 20/09/2019. Breast Cancer Genomics. Genomics in England and Genomic Lab Hub. Genomic Test Directory. Genomic Biomarkers in Breast Cancer. Future technologies . 1 Agilent DNF - 4 8 8 HS Kit Quick Guide for the Fragment Analyzer Systems The Agilent Fragment Analyzer systems are automated capillary electrophoresis platforms for scalable, flexible, fast, and Dr. Breno Fragomeni. Assistant Professor. Animal Science - UConn. Where are the labels?. Introduction . Why genomic prediction?. Higher accuracy. Shorter generation interval . Higher genetic gain. Genetic gain per year. biology – lessons from dairy cattle breeding. Dairy Cattle. 9 million cows in US. Attempt to have a calf born every year. Replaced after 2 or 3 years of milking. Bred via AI. Bull semen collected several times/week. Diluted and frozen.