PPT-  fMRI signatures of depression and response to antidepressants in early psychosis

Filippo Queirazza Background Around half of patients presenting with EP will develop depressive symptoms Similarly negative symptoms are highly prevalent ie 51 in EP and often run a chronic course . Richard C. Shelton, M.D.. James G. Blakemore Research Professor. Vice Chair for Clinical Research. Department of Psychiatry. Professor, Departments of Pharmacology and Psychology. Vanderbilt University. They are very, very common.. What are the symptoms of depression?. What are the symptoms of anxiety?. How do you treat it?. Are antidepressants stimulants or depressants?. 1. Introducing Dopamine and Serotonin. Antidepressants. Antidepressants. Primarily used to relieve symptoms of depression. Can also help patients with anxiety disorders. Not indicated for uncomplicated bereavement. Antidepressant Groups. Tricyclic antidepressants. Antidepressants. Primarily . used. to relieve symptoms of . depression. Can also help patients with . anxiety. disorders. Not indicated for uncomplicated bereavement. Depression. Most common psychiatric disorder . Richard C. Shelton, M.D.. James G. Blakemore Research Professor. Vice Chair for Clinical Research. Department of Psychiatry. Professor, Departments of Pharmacology and Psychology. Vanderbilt University. Grace Davis April 19, 2011 Medicinal Chemistry CHEM 5398 Antidepressants Depression and Symptoms Foremost cause of disability as measured by years lived with a disability Affects 121 Million people worldwide Selen AK. 1803337. PSYC-374. Outline. Introduction. Definition of depression. Symptoms. Treatment. How Serotonin& . Norephinephrine. Works?. Types of antidepressants. TCAs. MAOIs. SSRIs. Tolerance and withdrawal symptoms. Anxiolytic. Agents. History. Prior to antidepressant agent discovery in the 1950s, electroconvulsive shock was administered as well as opiates to induce euphoria in patients with anxiety. The 1950s was known as the Golden decade for the psychopharmacology industry. Nathan Kline went further to show that it had a stimulatory effect on depressed patients. . Mark Williams, MD. Why Shared Decision Tool on Antidepressants?. Depression a common and disabling problem. 10% of primary care population. Among top reasons for disability worldwide. Depression highly stigmatized and poorly defined. What are the symptoms of depression?. What are the symptoms of anxiety?. How do you treat it?. Are antidepressants stimulants or depressants?. 1. Introducing Dopamine and Serotonin. 2. DA and 5-HT. One thousand times less common than the major neurotransmitters. . SSRI’s (. fluoxetine. ) and SNRI’s (. venlaflaxine. ) are first line. treatment for most . anxiety disorders. Major (. Unipolar. ) Depression. Dysthymia . (Persistent Depressive Disorder). Bipolar Affective Disorder. depressed as they do manic/hypomanic (Baldessarini etal. ). In bipolar II patients, depression may be even more dominant. As an example, one study found a 37:1 ratio of depressive to hypomanic weeks Social. . significance. of . depression. The . overal. . prevalence. of . depression. . in. . the. . developed. . world. : 17,9%. 40% of . persones. . have. . concomitant. . mood. . disorder. Adults. JRI’s Northeast Area . Early Psychosis Flexible Support Team. CFFS’S SPECIALTY TEAMS . Children’s Friend and Family Services is a Division of Justice Resource Institute (JRI). Locations: .