PPT-24.2 Oxidation of Fatty Acids

A large amount of energy is obtained when fatty acids undergo oxidation in the mitochondria to acetyl CoA beta oxidation β oxidation which removes twocarbon segments containing the alpha and beta carbon from the carboxyl end of the fatty acid. C483 Spring 2013. Which of these is NOT a difference between fatty acid synthesis and beta oxidation?. Synthesis requires an enzyme with a biotin cofactor, but oxidation does not.. Synthesis utilizes NADP+/NADPH, but oxidation uses NAD+/NADH.. C483 Spring 2013. Which of these is NOT a difference between fatty acid synthesis and beta oxidation?. Synthesis requires an enzyme with a biotin cofactor, but oxidation does not.. Synthesis utilizes NADP+/NADPH, but oxidation uses NAD+/NADH.. Digestion and Absorption of Dietary Lipids.  . Lipids are taken in the diet . mainly as . triacylglycerol. . In addition, small amounts of phospholipids, cholesterol, . carotenoids. and fat-soluble vitamins are taken in diet.. . Introduction. Central energy yielding pathway in many tissues. As fuel. Chemically inert. Releases lots of energy. Oxidation of fatty acids. Occurs in 3 steps. Oxidative removal of successive 2 carbon units in the form of acetyl . kingdoms . in the biosynthesis of . fatty . acids (FA), . fats & oils. signaling molecules derived from FA such as prostaglandins. . anthraquinones. and . phenols found in certain botanicals. coenzyme A. by forming a fatty . acyl-CoA. . thioester. . . Beta Oxidation of Fatty Acids. PROF. . S. KAJUNA . The activation occurs the cytoplasm. L-3-hydroxy-4-trimethylammoniumbutyrate. Activation (the fatty . References: Garrett/Grisham . Biochemistry . (4. th. . ed. ). , . chs. . 23 and sections of 24. Berg, . Tymoczko. & . Stryer. . Biochemistry . (6ht . ed. )., sections of . Specific . Lipid . Digesting . Enzymes. in . Small Intestine. Digestion of Lipids . is . cleavage of Ester bonds . present in their structures.. Dietary . forms of . Lipids are digested:. By action . Of Beta Oxidation Of Fatty Acids. Three Stages . Of Beta Oxidation . For. Oxidation Fatty . acid Palmitate. Stage I. Activation of . Long Chain Fatty acid (Acyl . Chain. ). To. Acyl-CoA In Cytosol. Ketone Body Metabolism. Ketogenesis And Ketolysis. OR. Formation And Breakdown Of Ketone Bodies. Formation And Fates. Of . Ketone Bodies . In Human Body. What are Ketone Bodies ? . When ? Where? . Why? . Course Code: ZOOL 4008 (Biochemistry and Metabolism⤀ M.Sc. (Zoology), Semester – II Dr. Shyam Babu Prasad Assistant Professor Department of Zoology Mahatma Gandhi Central University (MGCU), M Lecture #14. Lehninger. . Principles of Biochemistry. Chapter 14-23. Overview of Metabolic Pathways-III. Chapter 17. Fatty Acid Catabolism. Digestion, Mobilization & Transport of Fats. Digestion, Mobilization & Transport of Fats. . Munther. . Lipids. Lipids are compounds that are insoluble in water, but soluble in an organic solvent (e.g., ether, benzene, acetone, chloroform). “lipid” composed mainly from C, H, O . • The main feature, in all lipids, is the large number of carbon-hydrogen bonds which makes them . Lipogenesis. . . Triacylglycerol. synthesis. Definition:. . Lipogenesis. is the synthesis of TAG from fatty acids and glycerol.. Site:. Sub-cellular site:. . cytoplasm. Organ (tissue) site:.