PPT-Cholesterol and Steroid Metabolism

UNIT III Lipid Metabolism HDL comprise a heterogeneous family of lipoproteins with a complex metabolism that is not yet completely understood HDL particles are formed in blood by the addition of lipid to . Learning outcome. Most cholesterol is synthesised by the liver from saturated fats in the diet. Cholesterol is a component of cell membranes and a precursor for steroid synthesis. High-density lipoprotein (HDL) transports excess cholesterol from the body cells to the liver for elimination. This prevents accumulation of cholesterol in the blood. Low-density lipoprotein (LDL) transports cholesterol to body cells. Most cells have LDL receptors that take LDL into the cell where it releases cholesterol. Once a cell has sufficient cholesterol a negative feedback system inhibits the synthesis of new LDL receptors and LDL circulates in the blood where it may deposit cholesterol in the arteries forming atheromas. A higher ratio of HDL to LDL will result in lower blood cholesterol and a reduced chance of atherosclerosis. . Dr. Nikhat Siddiqi. 1. Overview. Cholesterol, the characteristic steroid alcohol of animal tissues, performs a number of essential functions in the body. . C. holesterol is a structural component of all cell membranes, modulating their fluidity, and, in specialized tissues, cholesterol is a precursor of bile acids, steroid hormones, and vitamin D. . BIOSYNTHESIS OF CHOLESTEROL. Cholesterol is doubtless the most publicized lipid, notorious because of the strong correlation between high levels of cholesterol in the blood and the incidence of human cardiovascular diseases.. Chapter 29, . Stryer. Short Course. Lipid anabolism. Triacylglyderides. Membrane components. Cholesterol. Regulation. Steroids. TAG Synthesis. Mainly in Liver. Packaged in chylomicrons. Cholesterol Biosynthesis. We have touched on their metabolism.. Now we will wrap that up a bit by describing once you have digested carbohydrates, lipids, and proteins, what does your body do with it.. Metabolism. Metabolism:. Researcher Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University Patient education in diabetes and lifestyle interventionsDesigning a self sustained model of a basic diabetes m Ray . Hreiche. (updated slides from . Mohana. . Ratnapalan. & Anna . Sher. ). (THANK YOU!!!). Learning Objectives . Explain the physiological functions of cholesterol in membrane stability.. Outline the synthesis of cholesterol from acetate.. Result of misuse. 28 March 2018. IADVL TASKFORCE AGAINST TOPICAL STEROID ABUSE(ITATSA). 28 March 2018. IADVL TASKFORCE AGAINST TOPICAL STEROID ABUSE(ITATSA). 28 March 2018. IADVL TASKFORCE AGAINST TOPICAL STEROID ABUSE(ITATSA). differes. in their amount of inherent . metabolic (. glucocorticoid. ) . and . electrolyte regulating (. mineralocorticoid. ) . activity. . . The actions of these hormones extend to . almost every cell . Functions of Cholesterol. . a precursor of. steroid hormones. (progesterone, testosterone, . estradiol. , cortisol, etc.) . a precursor of. bile acids. . a precursor of . vitamin . D. important component of many mammalian . . of . Steroid . Hormones. Chemical Bioregulation in Physiological functions. Course No. – VPY- 609. Credit Hrs. – 3+0=3. Dr.. . Pramod. Kumar. Asstt. . Professor. Deptt. . of Veterinary Physiology. ????????????????? ? Cholesterol is a fatty substance, vital for good health. It helps form cell membranes, various hormones, bile and vitamin D. We get some cholesterol from our diet but most is made Phenylalanine (Phe, F) and tyrosine (Tyr, Y) are structurally related aromatic amino acids . Phenylalanine is an essential amino acid while tyrosine is non - essential . Besides its incorporation i NTD 208. MISS TALABI J.Y. DEPARTMENT OF HUMAN NUTRITION AND DIETETICS. COLLEGE OF MEDICINE AND HEALTH SCIENCES. AFE BABALOLA UNIVERSITY ADO-EKITI. INTRODUCTION. Energy is the capacity to do work. Energy exists in a number of forms. .