PPT-Cytokines Slackers Facts by Mike

Ori Disclaimer The information represents my understanding only so errors and omissions are probably rampant It has not been vetted or reviewed by faculty The source is our class notes The document can mostly be used forward and backward I tried to mark questionable stuff with . Cytokine Receptors. These are the receptors present on membrane of responsive . target cells by which cytokines binds to exert their biological effects.. Cytokine Receptors Fall Within Five Families. . Abul K. . Abbas. UCSF. FOCiS. 2. Lecture outline. Cytokines . Subsets of CD4 T cells: definitions, functions, development . New therapeutic strategies targeting cytokines . 3. The life history of T lymphocytes. Ori. Disclaimer. The information represents my understanding only so errors and omissions are probably rampant. It has not been vetted or reviewed by faculty. The source is our class notes.. The document can mostly be used forward and backward. I tried to mark questionable stuff with (?). . Ori. Disclaimer. The information represents my understanding only so errors and omissions are probably rampant. It has not been vetted or reviewed by faculty. The source is our class notes.. The document can mostly be used forward and backward. I tried to mark questionable stuff with (?). . Ori. Disclaimer. The information represents my understanding only so errors and omissions are probably rampant. It has not been vetted or reviewed by faculty. The source is our class notes.. The document can mostly be used forward and backward. I tried to mark questionable stuff with (?). . M.wt. . glycoproteins which are produced by cells of the innate and adaptive immune systems and, in particular by CD4. +. T cells, which orchestrate many effector mechanisms.. Cytokines serve as chemical messengers within the immune system.. Class name – VILS. Course name - ZOO-Biotech. (Rohit). How T-cells are activated. Two signals are required for T-cell activation namely Signal 1 and Signal 2. . Signal 1 . is provided by antigen-specific TCR . Objectives. General Properties of Cytokines and Chemokines. Six Families of Cytokines . Cytokine Antagonists . Cytokine-Related Diseases . Cytokine-Based Therapies. Dr. Refif S. Al-. Shawk. . Lec. Cytokines despite being nonspecific immunity it regulate the intensity and duration of the inflammatory/immune response.. Most cytokines are single polypeptide chains, may be aggregate as a homotrimer e.g. IL-12, IL-23. ®. Cytokines are rapidly secreted upon expression which results in. low / not detectable intracellular concentrations.. The use of secretion inhibitors allows for intracellular accumulation of cytokines:. Ori. Disclaimer. The information represents my understanding only so errors and omissions are probably rampant. It has not been vetted or reviewed by faculty. The source is our class notes.. The document can mostly be used forward and backward. I tried to mark questionable stuff with (?). . Ori. Disclaimer. The information represents my understanding only so errors and omissions are probably rampant. It has not been vetted or reviewed by faculty. The source is our class notes.. The document can mostly be used forward and backward. I tried to mark questionable stuff with (?). . Facts by Mike . Ori. Disclaimer. The information represents my understanding only so errors . and omissions are probably . rampant. It has not been vetted or reviewed by faculty. The source is our class notes.. Ori. Disclaimer. The information represents my understanding only so errors and omissions are probably rampant. It has not been vetted or reviewed by faculty. The source is our class notes.. The document can mostly be used forward and backward. I tried to mark questionable stuff with (?). .