PPT-From Gene to Protein Overview: The Flow of Genetic Information

The DNA inherited by organisms leads to specific traits by dictating synthesis of proteins The process by which DNA directs protein synthesis is called Gene Expression Transcription Translation. Marcus Chibucos, Ph.D.. University of Maryland School of Medicine. June 2014. Overview & goals. Understand. 1. How we predict . presence & structure . of coding & non-coding genes in the genome. Son. Genetic Engineering. It is the direct manipulation of an organism’s genome using modern DNA technology … also called genetic modification. A genome is the entirety of an organism’s hereditary information. Drosera. . rotundifolia. a tiny carnivore native to bogs!. Big Questions. How do plants exchange genes between populations?. How do we measure gene flow?. How does the spread of a beneficial allele via gene flow differ from that of a neutral allele?.  RNA and Protein Synthesis. Genes. are coded . DNA. instructions that control the production of . proteins. . DNA is like the master plan.. RNA. contains coded information for making proteins.. RNA . . . Parts of what’s known and a glimpse of what’s next…. Patrick Dion, . Ph.D. . Neurology and Neurosurgery. McGill . University. Human Genome Basics. 3 billions base . pairs.. Contains protein-coding and noncoding DNA.. CH. 5 & 6 REVIEW. ANSWER THE FOLLOWING QUESTIONS:. 1. What macromolecule group does DNA & RNA belong in?. 2. What monomer do we use to assemble the macromolecule group from question #1.. CH. 5 & 6 REVIEW. William Brooks. Medicinal Chemistry. March 31, 2011. Outline. Conventional drug design vs. gene therapy. Examples of genetic engineering. Types of gene therapy. Mechanisms. Delivery vectors. Viral. Non-viral. I. Wednesday . 3:30-4:20. p.m. Noland 342. II. Friday 1:20-2:10 p.m. Noland 539. Examples: Adaptation or not?. After high altitude training athletes have increased number of red blood cells (RBC). . . Parts of what’s known and a glimpse of what’s next…. Patrick Dion, . Ph.D. . Neurology and Neurosurgery. McGill . University. Human Genome Basics. 3 billions base . pairs.. Contains protein-coding and noncoding DNA.. Answer in writing: . what is DNA? Where is yours? . A . very long macromolecules that contains your genetic material. It’s found in the nucleus of each one of your cells.. A segment of DNA which codes for a protein, which determines a trait.. GENETIC. ENVIRONMENTAL. BOTH. CONGENITAL. HEREDITARY. FAMILAL. MUTATIONS. PERMANENT change in DNA. GENE. MUTATION: (may, and often, result in a single base error). CHROMOSOME . MUTATION: (visible chromosome change)part of chromosome. Vertical. Transfer of genetic information including genetic mutation from one generation to the next . Genetic inheritance. Information carried by DNA. Helps in preserving advantageous genotypic and phenotypic characteristics of bacteria in subsequent generations. Dr Anke . Hensiek. , Dr med, PhD, FRCP. Affiliated Assistant Professor University of Cambridge. Consultant Neurologist. Genetherapy. . Correct and precise correction of the DNA defect directly. Compensate a disease mechanism. Using Soil Nematodes. to Discover Genes Involved in. Human Alzheimer’s Disease. I. The Worm as a Model System. II. The Power of Genetic Analysis. III. An Example:. Research Project:. Genetic Analysis of .