PPT-Human chromosome 2 Mapping

Linkage One of the main observations from Mendel was independent assortment alleles of different genes will get assorted mixed up independently of one another We already showed that the genes are carried by the linear chromosomes. Mendel used pea plants to study genetics. Why were humans not equally ideal subjects? . Fruit Fly. Drosophila . melanogaster. . . Ideal organism used to study genetics. Suggested by Thomas Hunt Morgan. History of life on earth. If the earth was 24 hours old. ,. then . animals didn’t appear until the last 2 hours . dinosaurs went extinct in the the last 20 minutes – . anatomically modern humans -- the last one or two seconds . Marta Ruiz Fernández. Master. in . Advanced. . Genetics. 17 . December. 2014. INTRODUCTION. Inversions occur when a chromosome breaks at two points and the segment between the breakpoints is reinserted in the reverse orientation.. 14-1 Human Heredity. A. . Human chromosomes. -. chromosomes are analyzed by taking a photograph of condensed chromosomes during mitosis. -. the chromosomes are then cut out of the photograph and grouped together in pairs. GENOMICS 7 264-269 1990 SUSAN A LEDBETTER MARGARET R WALLAcEt FRANCIS S CoLmst AND DAVID H LEDBETTER institute for Molecular Genetics Baylor College of Medicine Houston Texas 77030 and tHoward Hughes Week’s Number. Lecture. 1. Introduction of human chromosomes. 2. Linkage, crossing over . 3. Chromosome mapping. 4. Sex determination systems and sex-linked inheritance . 5. Pedigree Analysis . 6. Pedigree Analysis . In humans, each cell normally contains . 23 pairs of chromosomes,. for a total of 46. . Twenty-two . (22) . of these pairs, called . autosomes. , look the same in both males and females. The . 23rd. Lecturer . Dr. Samah A. Jassam BSc MSc PhD . MRSB. Al-Mustansiriya University . Collage of Pharmacy. What is the secret behind the . transmission of hereditary characteristics from generation to . (. 2. ).. A relative Distance . between linked genes . on chromosome. . Also, Provides . clues about which chromosome contains the gene and . precisely where the gene lies . on that chromosome.. Chromosome mapping can . harbouring. the . Fusarium. head blight resistance QTL . Qfhs.ifa-5A. Christian Wagner. 1. , Petra Schwarz. 1. , Maria Buerstmayr. 1. , Barbara Steiner. 1. , Klaus Brugger. 1. , Lisa . Blazek. 1. , Delfina Barabaschi. The production of gametes (sex cells). Males = spermatogenesis in the testes. Females = oogenesis in the ovaries. Mitosis vs Meiosis. (Remember). . Diploid. Contain the full number (set) of chromosomes. The Human Genome Project THE ISRAEL ACADEMY OF SCIENCES AND HUMANITIES FOREWORD The concept of deciphering the Human Genome surfaced in the United States in the 1930s following the discoveries th Problems arose however regarding the following question:. Why are the number of alleles which undergo independent assortment greater than the number of chromosomes of an organism?. This was . explained by the . Important. Notes. For revision only. Objectives: . Describe the number, structure, and classification of human chromosomes . Explain what a Karyotype is and how it is obtained. . Describe chromosomal banding and explain its use. .