PPT-Identification of mutations prognostic of relapse after all

P Ferguson L Quek M Metzner I Ahmed C Garnett S Jeffries K Piechocki R Danby M Raghavan A Peniket M Griffiths A Bacon J Ward K Wheatley P Vyas C Craddock Introduction. GRADE: the past 15 and next … years. for prognostic evidence . Alfonso Iorio, . MD, PhD. Dept. of Clinical Epidemiology & Biostatistics,. McMaster University. Objectives. Role of prognostic evidence in guiding health care decisions. . The temporal dimension of . diagnosis. Gennaro D’Amico. Gastroenterology. Unit. V Cervello Hospital – Palermo. gedamico@libero.it. Prognosis and prognosis research. Prognosis. refers to the probability of an individual patient developing. What is Relapse Prevention?. A method of teaching recovering students to recognize and manage relapse warning signs. . Becomes a primary focus for students who are unable to maintain abstinence from alcohol or drugs despite primary treatment.. What is Relapse Prevention?. A method of teaching recovering students to recognize and manage relapse warning signs. . Becomes a primary focus for students who are unable to maintain abstinence from alcohol or drugs despite primary treatment.. http://io9.gizmodo.com/10-unusual-genetic-mutations-in-humans-470843733. Unharmful. Mutations. Mila . Kunis. has complete . heterochromia. . Kate Bosworth has . sectoral. . heterochromia. . Angelina Jolie has central . Point mutations. single base change . silent mutation. no amino acid change. redundancy in code. missense. change amino acid. Changes the final protien. nonsense. change to stop codon. Stopping prematurely . Given a mutation, identify its type. Predict how a mutation will affect a protein.. Mutations. Changes in genetic material (DNA). 2 main types of mutations. Point mutation- change in one or a few nucleotides (letters). The sequence of bases in DNA are like the letters of a coded message or even the letters of a simple alphabet. . If we change the sequence of the letters do we change the nature of the message?. That . Understand how they occur. Analyze the different types of mutations. Understand how mutations affect amino acid sequences and proteins. Objective. Central Dogma. DNA is transcribed into RNA, RNA is translated into proteins. KEY CONCEPT:. . Mutations. are changes in genetic material.. VOCABULARY:. Mutation, point mutation, . frameshift. mutation, polyploidy. Mutations – extension from gene expression. . Changes in genotype. Science. Learning intention. To understand the different types of mutations. . You will need. A pen and a piece of paper or a laptop to record your answers. . You may need the internet to search for answers. . Reporter: R4 . 張妙而. Introduction. . Mutations in . nucleophosmin. . 1 (. NPM1. ) . gene, one . of the most . common gene . mutations . . . (. 25%-30%) in . AML. NPM1. mut. . co-occurs with . Shade Agboola, Ann McNeill, Tim Coleman and Jo Leonardi-Bee. UK Centre for Tobacco and Alcohol Studies. University of Nottingham. Institute of Psychiatry, Psychology & Neuroscience. King’s College London. Lonnie Pyne. 1. , Jennifer C. Rodrigues. 2. , Kalen Larsen. 3. , Gordon Guyatt. 1. , . Lehana. Thabane. 1. , Nader Khalidi. 1. , Peter A. Merkel. 4. , Michael Walsh. 1. for the Vasculitis Patient-Powered Research Network (VPPRN)*.