PPT-Tagraxofusp in Blastic Plasmacytoid Dendritic Cell Neoplasm With/Without Central Nervous

Giulia Rivoli 1 Germana Beltrami 1 Anna Maria Raiola 1 Alida Dominietto 1 Marcell Riggi 2 Emanuele Angelucci 1 1 Ematologia e terapie cellulari IRCCS Ospedale Policlinico San Martino Genova . Functions of the Nervous System. Sensory input – gathering information. To monitor changes occurring inside and outside the body. Changes = stimuli. Integration. To process and interpret sensory input and decide if action is needed. Peripheral Nervous System. Autonomic Nervous System. Allied Health I. Central Nervous System. Communication and coordination system of the body. Seat of intellect and reasoning. Consists of the brain, spinal cord, and nerves. The . function of the nervous system is:. To sense, interpret, and respond to internal and external environmental changes to maintain a steady state in the . body (homeostasis). The nervous system is divided into two major structures: . The Nervous System Central Nervous System Peripheral Nervous System Procedure A starting person will be chosen and will be given an object. Once the teacher gives the signal, the start person will pass the object to their right. The Nervous System Central Nervous System Peripheral Nervous System Procedure A starting person will be chosen and will be given an object. Once the teacher gives the signal, the start person will pass the object to their right. The Nervous System Central Nervous System Peripheral Nervous System Procedure A starting person will be chosen and will be given an object. Once the teacher gives the signal, the start person will pass the object to their right. 1. Two main divisions. a. . Central Nervous System . (CNS) – consists of brain and spinal cord. b. . Peripheral Nervous System . (PNS) – includes nerves extending from . brain and . spinal . cord . History of Research on Nervous system. 460 -379 B.C. . Hippocrates discuss the epilepsy as disturbance of brain and also indicated that the brain is involved with sensation and is seat of intelligence. . A. Central Nervous System (CNS). 1. . Functions . A) . Acts . as command center. B) . Interprets . sensory information and dictates response based on past experience, . reflexes, . and current body conditions. Deemah. . Dabbagh. Nervous system. Composed of:. Brain (CNS). Spinal cord (CNS). Nerves to body parts (PNS. ). Function:. Maintain . homeostatis. by detecting stimuli in the environment. Structure. Central nervous system comprises the brain and the spinal cord with nervous tissue making up the system. This system is the most intricate system in human body.. The nervous tissue consists of rich network of billions of nerve cells in both the CNS and PNS . ®. Treatment of plasmacytoid dendritic cells with CpG DNA leads to the production of inflammatory cytokines like interferon alpha (IFN-. α. ). . IFN-. α. increases the expression of maturation markers on MDSCs, allowing them to mature and lose immunosuppressive function. . of Inflammation. ®. Dendritic Cells can often be divided into two subclasses: Plasmacytoid (. pDC. ) and Conventional (. cDC. ).. Brussel . et al. . showed that pDCs can stimulate cDCs to produce IL-12, which induces several cells of the immune system to produce IFN. 1. . Afferent. 1. . a brain area critical to learning to recognize threatening situations. 2. . amygdala. 2. . toward the nose. 3. . anterior . 3. . One of three meninges that surround and protect the spinal cord and the brain.