Presented by Jill S Perry MS NCC LPC CAADC SAP July 19 2017 What does COD Look Like JP Counseling Healing for Adults Youth and Families JP Counseling Healing for Adults Youth and Families ID: 621390
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Slide1
Helping Co-occurring Clients Manage Medications
Presented by
Jill S. Perry, MS, NCC, LPC, CAADC, SAP
July 19, 2017Slide2
What does COD Look Like?
JP Counseling
Healing for Adults, Youth and FamiliesSlide3
JP Counseling
Healing for Adults, Youth and FamiliesSlide4
JP Counseling
Healing for Adults, Youth and FamiliesSlide5
Poison Control
1-800-222-1222
From anywhere in the U.S.Slide6
DefinitionsSlide7
Psychotropic
From the Greek
psycho (the mind)
+ trop (a turning) = (capable of) turning the
mindSlide8
Food & Drug Administration (FDA)
Responsible for protecting the public health by assuring the safety, efficacy and security of human and veterinary drugs, biological products, medical devices, as well as our food supply, cosmetics, and products that emit radiationSlide9
"Off Label"
Use
A health care provider may choose a medication that has not been officially approved by the U.S. Food and Drug Administration (FDA) for
a particular use. Some insurance companies may
not pay for an “off label” medication use.The health care provider may have to complete a Prior Authorization form and receive approval prior to you being able to pick up the medication from the pharmacy. Slide10
Black Box
Warnings
T
he sternest warning by the U.S. Food and Drug Administration (FDA) that a medication can carry and still remain on the market in the United StatesAppears
on the label of a prescribed medication to alert you and your healthcare provider about any important safety concerns, such as serious side effects or life-threatening risksAlso known as a “black label warning” or “boxed warning,” is named for the black border surrounding the text of the warning that appears on the package insert, label, and other literature describing the medicationSlide11
Black Box
Warnings
The FDA requires a black box warning for one of the following situations:
The medication can cause serious undesirable effects (such as a fatal, life threatening or permanently disabling adverse reaction) compared to the potential benefit from the drug.
A serious adverse reaction can be prevented, reduced in frequency, or reduced in severity by proper use of the medication. For example, a medication may be safe to use in adults, but not in children.Slide12
Autonomic Nervous System (ANS)
Division of the peripheral nervous system that influences the function of internal organs.
The “Control System” that acts largely unconsciously and regulates bodily functions such as heart rate, digestion, respiratory rate, pupillary response, urination and sexual arousal.Slide13Slide14
Neurotransmitters
Chemical
messengers
used to communicate between brain cellsSlide15
Serotonin
One of
the chemical messengers (neurotransmitters) that carry signals between brain cellsSlide16
Gamma-Aminobutyric Acid (GABA)
Neurotransmitter that blocks impulses between nerve cells in the brain. Low levels of GABA may be linked to:
Anxiety or mood disorders
Epilepsy
Chronic painSlide17
Most Common Health Conditions Requiring Prescription Medication
Pain
High Cholesterol
High Blood PressureHypothyroidismGERD
InfectionDiabetes (primarily type 2)Slide18
Selective Serotonin Reuptake Inhibitors (SSRI)
Most commonly prescribed antidepressants
Minimal side effects
Eases depression by increasing levels of serotonin in the brainSSRIs block the reabsorption (reuptake) of serotonin in the brain, making more serotonin available. SSRIs are called selective because they seem to primarily affect serotonin, not other neurotransmittersSlide19Slide20
SSRIs
I
t
may take several weeks or longer before an antidepressant is fully effective and for initial side effects to ease up. You may need to try several dose adjustments or different antidepressants before you find the right oneMost side effects go away within few
weeksSSRIs differ in chemical makeup so if you can’t tolerate one, you may tolerate anotherSlide21
SSRIs
M
ay
be used to treat conditions other than depression, such as anxiety disorders.FDA has approved these SSRIs to treat depression:Citalopram (
Celexa)Escitalopram (Lexapro)Fluoxetine (Prozac) == also approved for OCDParoxetine (Paxil, Pexeva)Sertraline (Zoloft)Vilazodone (Viibryd)Slide22
SSRIs
Possible side effects of SSRIs may include, among others:
Drowsiness
NauseaDry mouthInsomniaDiarrhea
Nervousness, agitation or restlessnessDizzinessSexual problems, such as reduced sexual desire or difficulty reaching orgasm or inability to maintain an erection (erectile dysfunction)HeadacheBlurred visionSlide23
SSRIs
Drug interactions.
When taking an antidepressant, tell your doctor about any other prescription or over-the-counter medications, herbs or other supplements you're taking. Some antidepressants can cause dangerous reactions when combined with certain medications or herbal supplements
.Abnormal bleeding with certain pain relievers (aspirin, ibuprofen [Motrin, Advil], naproxen [
Naprosyn, Aleve], and blood thinners such as warfarin [Coumadin])Slide24
MariaSlide25
Serotonin syndrome
Rarely, an antidepressant can cause high levels of serotonin to accumulate in your body. Serotonin syndrome most often occurs when two medications that raise the level of serotonin are combined. Slide26
Serotonin Syndrome
Prescription & over-the-counter (OTC) drugs that can raise serotonin levels alone or in combination to cause
serotonin syndrome
include:Serotonin & norepinephrine reuptake inhibitors (SNRIs): duloxetine (Cymbalta), venlafaxine (Effexor), desvenlafaxine
succinate (Pristiq)Monoamine oxidase inhibitors (MAOIs): phenelzine (Nardil)Buspirone (Buspar) used for anxiety disordersDesyrel (Trazodone) used for depression or insomniaMigraine treatments: almotriptan (Axert), Amerge (naratriptan), rizatriptan (Maxalt), sumatriptan (Imitrex), and zolmitriptan (Zomig)Slide27
Serotonin Syndrome
Certain pain medications
,
including fentanyl , fentanyl citrate,
meperidine (Demerol), and tramadol (Ultram)Dextromethorphan , a cough suppressant found in many over-the-counter and prescription cough medicines or cold medicinesCertain medications prescribed for nausea, such as metoclopramide (Reglan), and ondansetron (Zofran)Antidepressants that affect multiple serotonin receptors, such as vortioxetine (Trintellix -formerly Brintellix) and vilazodone (Viibryd)Some illegal drugs, such as LSD and cocaineDietary supplements, including St. John's wort and ginsengSlide28
Serotonin Syndrome
People with serotonin syndrome are typically hospitalized for observation and treatment of symptoms. For example, benzodiazepines are given to treat agitation and/or
seizures
. Intravenous fluids are given to maintain hydration. Removing the drug responsible for the serotonin syndrome is critical.
Hydration by intravenous (IV) fluids) is also common. In severe cases, a medication called cyproheptadine (Periactin) that blocks serotonin production may be used.Slide29
Antidepressants and Pregnancy
.
Talk
to your doctor about the risks and benefits of using specific antidepressants. Some antidepressants may harm your baby if you take them during pregnancy or while you're breast-feeding. If you're taking an antidepressant and you're considering getting pregnant, talk to your doctor about the possible risks. Don't stop taking your medication without contacting your doctor first, as stopping might pose risks for you.Slide30
Suicide Risk
and
Antidepressants
Most antidepressants are generally safe, but the FDA requires that all antidepressants carry black box warnings. In some
cases, children, teenagers and young adults under 25 may have an increase in suicidal thoughts or behavior when taking antidepressants, especially in the first few weeks after starting or when the dose is changed.Anyone taking an antidepressant should be watched closely for worsening depression or unusual behavior. If you or someone you know has suicidal thoughts when taking an antidepressant, immediately contact your doctor or get emergency help.Keep in mind that antidepressants are more likely to reduce suicide risk in the long run by improving mood.Slide31
Discontinuation Syndrome
SSRIs aren't considered addictive. However, stopping antidepressant treatment abruptly or missing several doses can cause withdrawal-like symptoms.
Work
with your doctor to gradually and safely decrease your dose.Withdrawal-like symptoms can include:General feeling of uneasiness
NauseaDizzinessLethargyFlu-like symptomsSlide32Slide33
Serotonin & Norepinephrine Reuptake Inhibitors (SNRI)
Help relieve
depression symptoms, such as irritability and sadness, but some are also used for anxiety disorders and nerve pain
.Ease
depression by impacting neurotransmittersWork by ultimately effecting changes in brain chemistry and communication in brain nerve cell circuitry known to regulate mood, to help relieve depression.Slide34
SNRIs
N
orepinephrine and Noradrenaline are different names for the same neurotransmitter. N
orepinephrine has multiple rolesIt relays messages in the autonomic nervous system's fight-or-flight responseNorepinephrine prepares the brain to encounter and respond to stimuli from the environment, thereby facilitating vigilanceIn both roles, norepinephrine mediates arousal.Slide35Slide36
SNRIs
Desvenlafaxine
(
Pristiq, Khedezla)Duloxetine (Cymbalta) ― also approved to treat anxiety and certain types of chronic painLevomilnacipran
(Fetzima)Venlafaxine (Effexor XR) ― also approved to treat anxiety and panic disorderSlide37
SNRIs
Side effects are usually mild and go away after the first few weeks of treatment. Taking your medication with food may reduce nausea. If you can't tolerate one SNRI, you may be able to tolerate a different one, as each SNRI varies in chemical makeup
.
The most common possible side effects of SNRIs include:Nausea
Dry mouthDizzinessHeadacheExcessive sweatingSlide38
SNRIs
Other possible side effects may include:
Tiredness
ConstipationInsomniaChanges in sexual function, such as reduced sexual desire, difficulty reaching orgasm or the inability to maintain an erection (erectile dysfunction)
Loss of appetiteIncreased blood pressureWorsening of liver problemsSlide39
SNRIs
SNRIs may increase your risk of bleeding, especially when you're taking other medications that also increase the risk of bleeding, such as aspirin or warfarin (Coumadin,
Jantoven
).Serotonin syndrome
Antidepressants and pregnancy: Some antidepressants may harm your baby if you take them during pregnancy or while you're breast-feeding.Slide40
GeorgeSlide41
SNRIs
G
enerally safe
but the FDA requires that all antidepressants carry black box warnings. In some cases, children, teenagers and young adults under 25 may have an increase in suicidal thoughts or behavior when taking antidepressants, especially in the first few weeks after starting or when the dose is changed.
Anyone taking an antidepressant should be watched closely for worsening depression or unusual behavior. If you or someone you know has suicidal thoughts when taking an antidepressant, immediately contact your doctor or get emergency help.Slide42Slide43
Discontinuation Syndrome
Withdrawal-like symptoms can include
:
DizzinessHeadache
Flu-like symptoms, such as tiredness, chills and muscle achesIrritability or agitationNauseaDiarrheaSlide44
Monoamine oxidase inhibitors (MAOI)
F
irst
type of antidepressant developedGenerally been replaced by antidepressants that are safer and cause
fewer side effects.Requires diet restrictions because they can cause dangerously high blood pressure when taken with certain foods or medications.ease depression by affecting chemical messengers (neurotransmitters) used to communicate between brain cells. Like most antidepressants, MAOIs work by ultimately effecting changes in the brain chemistry that are operational in depression.
ease depression by affecting chemical messengers (neurotransmitters) used to communicate between brain cells. Like most antidepressants,
MAOIs
work by ultimately effecting changes in the brain chemistry that are operational in depression.
Slide45
MAOIs
Eases depression by impacting neurotransmitters used to communicate between brain cells.
Work most effectively by changing the brain chemistry that are operational in depression.
An enzyme called monoamine oxidase is involved in removing norepinephrine, serotonin and dopamine from the brain. MAOIs prevent this from happening, which makes more of these brain chemicals available to effect changes in both cells and circuits that have been impacted by depression.
MAOIs are sometimes used to treat conditions other than depression, such as Parkinson’s Disease.Slide46
MAOIs
The FDA has approved these MAOIs to treat depression:
Isocarboxazid
(
Marplan)Phenelzine (Nardil)Selgiline (Emsam)—transdermal (skin) patch which may cause few side effects Tranylcypromine (Parnate)Slide47
MAOIs
Diet restrictions include foods high in tyramine that can cause serious spike in blood pressure:
Strong or aged cheeses
Cured meats
Smoked or processed meatsPickled or fermented foodsSoy based saucesSoybeansSnow peas, broad beans (fava beans) and their podsDried or overripe fruitsMeat tenderiziersSlide48Slide49
MAOIs
Side effects:
Dry mouth
Nausea, diarrhea or constipationHeadacheDrowsinessInsomnia
Dizziness or lightheadednessSkin reaction at the patch siteSlide50
MAOIs
Other possible side effects:
Involuntary muscle jerks
Low blood pressureReduced sexual desire or difficulty reaching orgasmWeight gain
Difficulty starting a urine flowMuscle crampsPrickling or tingling sensation in the skin (paresthesia)Slide51
JaneSlide52
MAOIs
Serotonin Syndrome
Antidepressants
and pregnancy: Some antidepressants may harm your baby if you take them during pregnancy or while you're breast-feeding
.Drug Interactions: Other antidepressantsCertain pain drugsCertain cold & allergy medicationsSome herbal supplements Slide53
MAOIs
Generally safe but the FDA requires that all antidepressants carry black box warnings. In some cases, children, teenagers and young adults under 25 may have an increase in suicidal thoughts or behavior when taking antidepressants, especially in the first few weeks after starting or when the dose is changed
.
Anyone taking an antidepressant should be watched closely for worsening depression or unusual behavior. If you or someone you know has suicidal thoughts when taking an antidepressant, immediately contact your doctor or get emergency help.Slide54
Discontinuation Syndrome
Stopping treatment with MAOIs can cause flu-like symptoms, including anxiety, agitation, insomnia, sweating, chills, nausea, headache, and generally feeling unwell (malaise)
Rarely, addition withdrawal symptoms may occur including:
Confusion
Detachment from reality (psychosis)ConvulsionsSlide55
Discontinuation Syndrome
You may need to wait two or more weeks between the use of MAOIs and other antidepressants to avoid serotonin syndrome. During those two weeks, continue with food and beverage restrictions and avoid taking drugs that can cause interactions with MAOIs.Slide56
Anxiety Meds
Generalized anxiety disorder
(
GAD)
PhobiasObsessive-compulsive disorder(OCD)Post-traumatic stress disorder(PTSD)Panic disorder (PD)Social anxiety disorder (SAD)Slide57
Anxiety Meds
Antidepressants
and
anxiolytic medications work primarily by affecting the balance of serotonin, norepinephrine and GABA.
Beta-blockers and other types of drugs are used to address the physical symptoms that may accompany an anxiety attack by blocking the receptors that are associated with some of the physiological symptoms of anxiety -- including rapid heartbeat.First-generation antihistamines are also used to help with anxiety symptoms because they have a sedating effect.Slide58
Anxiety Meds
SSRIs
are the first-line for treating most types of anxiety, including:
Panic disorder
Obsessive-compulsive disorderSocial anxiety disorder, general anxiety disorderPost-traumatic stress disorderSlide59
Anxiety Meds
Tricyclic antidepressants
are used in treating:Panic disorder
Post-traumatic stress disorderGeneral anxiety disorder. Clomipramine (Anafranil), may also be used to treat obsessive-compulsive disorder.Slide60
Anxiety Meds
MAOIs
are used
for:Panic disorderSocial
anxiety disorderPost-traumatic stress disorderSlide61
Anxiety Meds
Buspirone
(BuSpar), an anti-anxiety drug, is used in the treatment of general anxiety disorder. Buspirone
(BuSpar) enhances the activity of serotonin. Large amounts of grapefruit juice may increase blood levels of buspirone. First-generation antihistamines, such as diphenhydramine, can be used to treat general anxiety disorder. The antihistamine hydroxyzine (Atarax, Vistaril), has a sedative effect by blocking certain receptors in the brain.Slide62
Anxiety Meds
B
enzodiazepines
are used to treat:General anxiety
disorderSocial anxiety disorderPanic disorder. Benzodiazepines act on the neurotransmitter gamma aminobutyric acid (GABA).Benzodiazepines should not be abruptly stopped because of the risk of seizures and other serious side effects. It is dangerous to combine benzodiazepines with other central nervous system depressants, including alcohol. Doing so may cause profound drowsiness and/or impair breathing. Those who have breathing difficulties such as sleep apnea or chronic obstructive pulmonary disease (COPD) should not use benzodiazepines.Benzodiazepines frequently cause drowsiness; therefore, care should be taken when operating machinery or motor vehicles.Slide63
Benzodiazepines
Alprazolam (
Xanax
®)
Clonazepam (Klonopin®) Diazepam (Valium® and Distat®)Slide64
Anxiety Meds
Alprazolam
increases blood levels of the antidepressants imipramine and
desipramine. Alprazolam may also interact with some calcium channel blockers and with grapefruit juice. Carbamazepine decreases blood levels of
alprazolam.Combining benzodiazepines with alcohol or other central nervous system depressants can cause increased sedation and potentially dangerous respiratory depression.Fluoxetine, propoxyphene, and oral contraceptives increase blood levels of alprazolam (Xanax), as do ketoconazole, itraconazole, nefazodone, fluvoxamine, and erythromycin.Slide65
SallySlide66
Anxiety Meds
Beta-blockers, such as propranolol, are used to
treat:
Performance anxiety, a kind of social anxiety
disorderSometimes used for panic disorder. off-label uses for treating panic disorders They may also have some use in PTSDSlide67
Anticonvulsants as Anxiety Meds
Gabapentin (Neurontin)
is an anticonvulsant used to treat anxiety.
It may affect blood levels of hydrocodone and
morphine. Gabapentin levels can decrease when given with the antacid Maalox. Allow 2 hours between the drugs.The following medications significantly decrease blood levels of some anticonvulsants:Oral contraceptivesPhenobarbitalSlide68
Stimulants
P
rescribed
to treat children, adolescents, or adults diagnosed with ADHDIncrease alertness, attention, and energy, as well as elevate blood pressure, heart rate, and respiration
Stimulants used to treat ADHD include:Methylphenidate (Ritalin)Amphetamine Dextroamphetamine (Adderall, Dexedrine)Lisdexamfetamine Dimesylate (Vyvanse)Slide69
Stimulants
A
lso
prescribed to treat other health conditions, including:NarcolepsyOccasionally depression (especially in older or chronically medically ill people and in those who have not responded to other treatments
)Research shows that teens with ADHD who took stimulant medications were less likely to abuse drugs than those who did not take stimulant medications.Slide70
Stimulants
Most side effects are minor and disappear when dosage levels are lowered. The most common side effects include:
Difficulty falling asleep or staying asleep
Loss of appetiteStomach painHeadache
Less common side effects include:Motor tics or verbal tics (sudden, repetitive movements or sounds)Personality changes, such as appearing “flat” or without emotionSlide71
Mood Stabilizers
U
sed
primarily to treat:Bipolar disorderM
ood swings associated with other mental disordersTo augment the effect of other medications used to treat depression.Work by decreasing abnormal activity in the brain and are also sometimes used to treat:Depression (usually along with an antidepressant)Schizoaffective DisorderDisorders of impulse controlSlide72
Mood Stabilizers
S
everal
side effects, and some of them may become serious, especially at excessively high blood levels. These side effects include:Itching, rashExcessive thirstFrequent urination
Tremor (shakiness) of the handsNausea and vomitingSlurred speechFast, slow, irregular, or pounding heartbeatBlackoutsChanges in visionSeizuresHallucinations (seeing things or hearing voices that do not exist)Loss of coordinationSwelling of the eyes, face, lips, tongue, throat, hands, feet, ankles, or lower legs.Slide73
Mood Stabilizers
Cause damage to the liver or pancreas, so people taking it should see their doctors
regularly
Increase testosterone (a male hormone) levels in teenage girls and lead to a condition called polycystic ovarian syndrome (a disease that can affect fertility and make the menstrual cycle become irregular)
Medications for common adult health problems, such as diabetes, high blood pressure, anxiety, and depression may interact badly with anticonvulsantsSlide74
Anticonvulsants as Mood Stabilizers
Originally developed
to treat seizures, but they were found to help control unstable moods as
wellMost commonly used as a mood stabilizer is
valproic acidFor some people, especially those with “mixed” symptoms of mania and depression or those with rapid-cycling bipolar disorder, valproic acid may work better than lithiumSlide75
Anticonvulsants as Mood Stabilizers
Some possible side effects linked anticonvulsants (such as
valproic
acid) include:Drowsiness
DizzinessHeadacheDiarrheaConstipationChanges in appetiteWeight changesBack painAgitationMood swingsAbnormal thinkingUncontrollable shaking of a part of the bodyLoss of coordinationUncontrollable movements of the eyesBlurred or double visionRinging in the earsHair lossSlide76Slide77
Pain Medications
Work by blocking pain signals going to the brain of by interfering with the brain’s interpretation of the signals
Most painkiller use isn’t
misuse
Effective to treat residual pain after surgery, as well as chronic painHighly habit-forming Deadly at high doses or in conjunction with other drugsSlide78
Pain Medications
Celebrex (celecoxib): Arthritis, short term pain, painful menstruation
Ultram (tramadol): schedule IV controlled substance (low potential for abuse; limited physical or psychological dependence—as compared to other substances in other classifications)
Demerol (meperidine
HCl)Lorcet (hydrocodone bitartrate & acetaminophen)Vicodin (hydrocodone & acetaminophen)Slide79
Pain Medications
Norco (hydrocodone
bitartrate
& acetaminophen)Percocet (oxycodone & acetaminophen)Percodan (aspirin & oxycodone hydrochloride)
Oxycontin (oxycodone HCl)Opana (oxymorphone)/Opana ERSlide80
Pain Medications
MS
Contin
(morphine sulfate)Fentanyl (Actiq)Dilaudid
(hydromorphone)Slide81
Pain Medications
More than 1 in 3 American adults – 35%-- were given painkiller prescriptions by medical providers last year.
More American adults used prescription painkillers than cigarettes, smokeless tobacco or cigars
combined
Women are more likely to have chronic pain, be prescribed prescription pain relievers, be given higher doses, and use them for longer time periods than men. Women may become dependent on prescription pain relievers more quickly than menSlide82
Pain Medications
Opioid painkillers killed nearly 19,000 Americans in 2014
That number is greater than the number of Americans murdered in 2015 (15,809)
2008: Americans consume about 80% of global opioid supply and 99% of supply of hydrocodoneSlide83
Reason for Using Prescription Pain
Relievers
Easy to get from parents' medicine cabinets--62%
Available everywhere--52%
They are not illegal drugs--51%Easy to get through other people's prescriptions--50%Teens can claim to have a prescription if caught--49%They are cheap--43%Safer to use than illegal drugs--35%Less shame attached to using--33%Easy to purchase over the Internet--32%Fewer side effects than street drugs--32%Can be used as study aids--25%Parents don't care as much if you get caught--21%Slide84
BradySlide85
Herbal Products
Ginkgo Biloba: improve cognitive functioning and blood flow
St. John’s Wort: anxiety and depression
Ephedra: weight-loss “herbal fen-phen”; decongestants, bronchodilators and stimulants, “herbal ecstacy
”—euphoric state and heightening of awareness & sexual sensationsGinseng: strengthen normal body functions, increase resistance to stress & improve sexual functionKava: antianxiety & calming effectsSlide86
Herbal Products
HERBAL PRODUCT
SIDE EFFECTS
Ginkgo biloba
BleedingSt. John's wortGastrointestinal disturbances, allergic reactions, fatigue, dizziness, confusion, dry mouth, photosensitivityEphedra (ma huang)Hypertension, insomnia, arrhythmia, nervousness, tremor, headache, seizure, cerebrovascular event, myocardial infarction, kidney stones
Kava
Sedation, oral and lingual dyskinesia, torticollis, oculogyric crisis, exacerbation of Parkinson's disease, painful twisting movements of the trunk, rash
Side Effects of Select Herbal ProductsSlide87
Herbal Products
HERBAL PRODUCT
INTERACTING DRUGS
Ginkgo biloba
Aspirin, warfarin (Coumadin), ticlopidine (Ticlid), clopidogrel (Plavix), dipyridamole (Persantine)St. John' s wortAntidepressantsEphedraCaffeine, decongestants, stimulants
Ginseng
Warfarin
Kava
Sedatives, sleeping pills, antipsychotics, alcohol
Drug Interactions with Herbal ProductsSlide88
OscarSlide89
Herbal Products
Are you taking an herbal product, herbal supplement or other “natural remedy?”
If so, are you taking any prescription or nonprescription medications for the same purpose as the herbal product?
Have you used this herbal product before?
Are you allergic to any plant products?Are you pregnant or breast-feeding?Questions to Ask Patients Who May Be Taking Herbal ProductsSlide90
Medication-assisted treatment
Medication
Counseling
Support
Often the best option for today’s opioid addictionSlide91
Medication-Assisted Treatment (MAT)
Opioids
Methadone/
BuphrenorphineActs on the same targets in the brain as heroin and morphine; suppresses withdrawal symptoms and relieves cravings
NaltrexoneBlocks the effects of opioids at their receptor sites in the brainShould only be used in patients who have already been detoxedSlide92
MAT
Methadone
Daily methadone dose determined by the program physician based upon a physical exam and the individual’s history
Administered only in oral form and dosing is initially observed by medical staff
Each individual must receive a minimum of 2.5 hours of counseling/month12-month minimum treatment recommended for maintenanceSlide93
MAT
Buprenorphine
Physicians must request a special certification to prescribe
Subutex
: primarily for pregnant womanSuboxone (Buprenorphine & Naloxone)Buprenex (injectable available)Butrans (7 day transdermal patch)Slide94
Buprenorphine O
verdose
The risk of overdose and death is increased when
suboxone is combined with other drugs, such as
alcohol and benzodiazepines, to give a more intense high. Seek immediate medical treatment if you experience the following symptoms:Profound drowsiness.Intermittent loss of consciousness.Lack of coordination.Slurred speech.Vision problems.Slowed breathing.Sluggish reflexes.Slide95
MAT
Naloxone
Revia
(daily pill)
Vivitrol (monthly injection)Slide96
ValerieSlide97
MAT
Alcohol
Naltrexone: Blocks opioid receptors that are involved in the rewarding effects of drinking and in the craving for alcohol
Acamprosate
(Campral): May reduce symptoms of long-lasting withdrawal, such as insomnia, anxiety, restlessness and dysphoriaDisulfiram (Antabuse): Interferes with the breakdown of alcohol. Leads to unpleasant reactions that include flushing, nausea, and irregular heartbeat if the patient drinks alcoholSlide98
Slide99
Naloxone (Narcan
)
Opioid overdose reversal
Opioid antagonist: binds to opioid receptors and can reverse and block the effects of other opioids
Can restore normal respiration to someone whose breathing has slowed or stopped as a result of overdosingInjectable or Nasal SprayStanding Order in PASlide100
StanleySlide101
Special PopulationsSlide102
Children & Adolescents
Many medications used to treat children and adolescents with mental illness are safe and effective. However, some medications have not been studied or approved for use with children or adolescents
.
Still, a doctor can give a young person an FDA-approved medication on an "off-label" basis. Slide103
Children & Adolescents
Children may have different reactions and side effects than adults
.
Some medications have current FDA warnings about potentially dangerous side effects for younger patients. Slide104
SkylerSlide105
Older Adults
People over 65 have
a
higher risk for experiencing bad drug interactions, missing doses, or overdosing.Older adults also tend to be more sensitive to medications. Even healthy older people react to medications differently than younger people because older people's bodies process and eliminate medications more slowly. Slide106
Older Adults
Older adults p
urchase more than 30 percent of all prescription medication and more than 40 percent of over the counter (OTC) medicines. Estimates are that as many as 90 percent of seniors use either herbal remedies or vitamins.
Seniors take an average of four to five medications on a daily basis.Slide107
Women Who Are Pregnant or Who May Become Pregnant
The research on the use of psychiatric medications during pregnancy is
limited
There are different
risks depending on which medication is taken and at what point during the pregnancy the medication is takenSlide108
Women Who Are Pregnant or Who May Become Pregnant
Most women should avoid certain medications during pregnancy. For example
:
Mood stabilizers are known to cause birth defects.
Benzodiazepines and lithium have been shown to cause "floppy baby syndrome," in which a baby is drowsy and limp, and cannot breathe or feed well. Benzodiazepines may cause birth defects or other infant problems, especially if taken during the first trimester.Slide109
Women Who Are Pregnant or Who May Become Pregnant
According
to research, taking antipsychotic medications during pregnancy can lead to birth defects, especially if they are taken during the first trimester and in combination with other drugs, but the risks vary widely and depend on the type of antipsychotic taken. The conventional antipsychotic haloperidol has been studied more than others, and has been found not to cause birth defects. Research on the newer atypical antipsychotics is ongoing.Slide110
Women Who Are Pregnant or Who May Become Pregnant
Antidepressants, especially SSRIs, are considered to be safe during pregnancy. However, antidepressant medications do cross the placental barrier and may reach the fetus. Birth defects or other problems are possible, but they are very rare. The effects of antidepressants on childhood development remain under study
.Slide111
Women Who Are Pregnant or Who May Become Pregnant
Studies have also found that fetuses exposed to SSRIs during the third trimester may be born with "withdrawal" symptoms such as breathing problems, jitteriness, irritability, trouble feeding, or hypoglycemia (low blood sugar). Most studies have found that these symptoms in babies are generally mild and short-lived, and no deaths have been reported. Risks from the use of antidepressants need to be balanced with the risks of stopping medication; if a mother is too depressed to care for herself and her child, both may be at risk for problems.Slide112
Women Who Are Pregnant or Who May Become Pregnant
W
omen
who nurse while taking psychiatric medications should know that a small amount of the medication passes into the breast milk. However, the medication may or may not affect the baby depending on the medication and when it is taken
. Slide113
TammySlide114
Members Of Specific Cultural Groups
Certain
ethnic groups respond differently to medication, though more research is needed.
African
Americans and some Asian Americans, for instance, metabolize some medications more slowly than Caucasians. They are thus at increased risk of certain side effects and may benefit from lower dosages. For many ethnic groups treatment is also complicated by language barriers, socio-economic stresses, lack of minority health care professionals and stigma.Slide115
Managing Meds
M
edication
must be actively managed, particularly in respect to coping with side effects. Difficulty coping with unpleasant side-effects is a common reason for people coming off their
medication.To guard against an interaction, make a list of all medications, vitamins and herbal remedies.Beside each medication, write the contact information of the physician who prescribed the medicine.Slide116
Who Should Prescribe Mental Health and/or Pain Medications
Primary Care Physician (PCP)
Psychiatrist
Pain SpecialistAddictionologistSlide117
DominicSlide118
Managing Meds
Avoid Pharmacy
Shopping
Poly-pharmacy, the “technical” name for pharmacy shopping, is often a source of confusion and drug interactions. Throw Away Outdated
MedicinesBorrowing or Lending MedicinePrescription medication should never be taken by anyone else than for whom it was intended. Other individuals have special medical histories and may also be taking other medicines that can cause serious drug interactions.Slide119
Managing Meds
Don’t Skip
Doses to Save Medication
Check, Check, and RecheckBefore taking a medication, double-check the label to be sure that you are taking it according to your doctor’s
instructionsTry to take your pills at the same time each day and pick a time when you are almost always home (for example, when you wake up in the morning or when you go to sleep at night).Slide120
Managing Meds
Set automated reminders. You can set a daily alarm on your cell phone or computer. Many free online calendars allow you to set daily email or text message alerts (e.g., Google Calendar).
Carry
a record of your medications with you by using our Medication Wallet Reminder Card.Slide121
Talking to Your Doctor
If
you are prescribed a medication, be sure that you:
Tell the doctor about all medications and vitamin supplements you are already taking.Remind your doctor about any allergies and any problems you have had with medicines.
Understand how to take the medicine before you start using it and take your medicine as instructed.Don't take medicines prescribed for another person or give yours to someone else.Call your doctor right away if you have any problems with your medicine or if you are worried that it might be doing more harm than good. Your doctor may be able to adjust the dose or change your prescription to a different one that may work better for you.Slide122
Compliance
In the past when doctors treating mental health conditions were seen
as
the authority figures, they used to use the term “compliance” to describe how good a patient was at taking their medication. It is now recognized
that compliance tends to be a problem for all people with long-term medical conditions whether their conditions are mental or physical.Studies have shown that compliance with medication is no worse in mental health conditions like schizophrenia than it is in long term physical ailments such as asthma or high blood pressure.Demographic factors such as whether you are single or in a relationship are more likely to play a role in your compliance.Slide123
1. Get on to the right medication for you.
Doctors have a range of medications available to them and different drugs will work in different ways. If the side effects you are experiencing with the drug are so serious that they are making life unpleasant then discuss with your doctor the possibility of changing to a different medicine.Slide124
2. Change the dose of the medication
T
he
aim with medication is to always be taking the optimum dose: that is the dose that gives you the maximum beneficial effect with the fewest side effects. If the side effects are making life unpleasant and you think that you have got as good as you are going to get with the symptoms then think about asking your doctor to try reducing the dose for a trial period to find out if the side effects can be reduced without the symptoms
returning.Slide125
3. Keep on taking the medication
It
may sound paradoxical but coming off your medication without first planning it with your doctor can actually lead to an increase in side effects.
It is important that you continue to take this low dose even when you are feeling fine and are symptom free. If you stop taking the maintenance dose you will risk a relapse and would then need to be treated with a much higher dose which in turn would have much worse side effects than the maintenance dose.Slide126
4. Treat the side effects of the medication
Many
side effects can be successfully overcome by treating them with other drugs.
Anxiety can be treated with anti-anxiety drugs called
anxioliticsNausea can be treated with over-the-counter anti-sea sickness preparationsSleep disruption can be eased with one of the sedating antihistaminesMen with sexual side effects may be treated with medications such as Viagra.Some people also find traditional herbal remedies Slide127
4. Treat the side effects of the medication
If your medicine upsets your
stomach
, ask your doctor if you should take it with a meal or if the risk may be less with a brand rather than a generic form of a drug.If your
medicine makes you sleepy during the day or keeps you awake at night, ask your doctor what time of day you should take it. By taking your medicine first thing in the morning or right before bed, you might diminish some of the unwanted effects.Don't take psychotropic medicines with alcohol. Alcohol can affect how well the medicine works, cause sedation, and possibly worsen depression, anxiety and other mental health issues.Slide128
Priapism: A Painfully Hard Topic
C
ondition
in which a penis remains erect for hours in the absence of stimulation or after stimulation has endedSlide129
5. Find out as much as you can about your diagnosis
T
he
more you know about a problem the better you will be able to cope with it. Slide130
6. Join a support group
This
is one area where support groups can prove very useful. Joining a support group for people with similar problems will give you the chance to talk about side effects with other people who have also experienced them and have found their own way of coping.Slide131
Cognitive Behavioral Therapy (CBT) for Improved Med Compliance
Inquire as to patients’ previous experience with medication.
Ask about prior history
Why was it prescribed?Was it helpful?Under what conditions was it terminated?
Did they take med as prescribed?Slide132
CBT for Improved Med Compliance
Address patients' concerns about medication
.
Listen carefully for any concerns, misunderstandings, or prejudices about taking medication and address these rapidly and assertively. These may include misconceptions about expected medication effects, time needed to experience the effect, side effects, dosing, and interactions with
other substances. Therapists should provide clarification in clear, familiar terms and frequently check back with patients to be sure they understand.Slide133
CBT for Improved Med Compliance
P
atients
should be encouraged to expect gradual rather than all-or-nothing change from medication. Explaining the gradual emergence of medication effects provides an opportunity for the therapist to emphasize that patients should not expect to benefit from an entirely passive stance regarding
treatment simply because they are taking medication. Mastery and implementation of coping skills remain an essential and important part of treatment; medication may be an additional, useful adjunct or tool.Slide134
CBT for Improved Med Compliance
Assess medication compliance since last session
.
Close, consistent, and careful monitoring is one of the most effective strategies for enhancing compliance with medications. Thus, a portion of each session should be devoted to evaluating medication compliance and working through any difficulties that might arise.Slide135
CBT for Improved Med Compliance
Praise medication
compliance
Therapists should also convey confidence in the medication and inform patients of the likely benefits. Therapists should be strongly on the side of compliance and praise patients' compliance enthusiastically and genuinely.Slide136
CBT for Improved Med Compliance
Relate patients' clinical improvement to compliance and lack of improvement to noncompliance
.
A crucial role of the therapist is to establish and stress the connection between medication compliance, psychotherapy sessions, and improvement. Therapists should make explicit causal links between patients' compliance and improvement in appropriate
target symptoms. Conversely, therapists might tie poor compliance to failure to improve.Slide137
CBT for Improved Med Compliance
Use a problem solving strategy for noncompliance
.
When patients are not compliant with medication, therapists should take a practical, objective approach. They should try to help patients clarify reasons or obstacles to compliance and generate practical solutions. For example, patients may report difficulty remembering to take the medication. Practical strategies to cue the patient (e.g., notes on the bathroom mirror, taking the medication at a regular mealtime, enlisting family support and reminders) should be generated and followed up on in the next session. In all of these discussions, therapists should be nonjudgmental and
nonconfrontational. Efforts should be made to help patients feel ownership of the plan. This can be done by having them take the primary role in developing the plan, rather than having therapists telling them what to do.Slide138
Motivational Interviewing
Assess Stage of Change
Express empathy
Support self-efficacy
Highlight discrepancies between the patient’s current health behaviors & core valuesRoll with resistanceSlide139
Disclosure
Doesn’t have
to be
all or nothingWeigh the risks and benefits involved with telling certain people.
We don’t always share with everyone about medical issues, like diabetes or hypertension. Mental health issues should be considered in the same manner.Slide140
Disclosure at Work
Americans
with Disabilities Act (ADA), passed in 1990, prohibits discrimination in hiring and firing decisions based on physical and
mental disabilities and entitles people to “reasonable accommodations” from their employers. In
the case of mental disabilities, these fixes may include flexible working hours, access to a quiet area and additional feedback from supervisors. In many cases, the modifications cost little to no money and can make a big difference to employee happiness and productivity.Slide141
Disclosure at Work
The ADA protections are not ironclad, however. Many managers are not familiar with the details of the law, and people who experience discrimination often lack the resources to bring their case to
court.
Discrimination is difficult to prove: about 90 percent of plaintiffs who bring suits under the ADA lose their cases.Slide142
Disclosure at Work
A critical consideration is the
workplace climate
. Try to gauge your employer's response ahead of time by looking for certain signs. Those with a history of hiring people from diverse backgrounds may be more understanding. But supervisors may frown on your disclosure if you hold a job with stringent requirements, such as security
clearance.Slide143
Disclosure at Work
Researchers suggest that employees considering broaching a mental health concern should know what they hope to gain.
If
your work has started to suffer, disclosing a mental illness may help you explain the situation and get assistance.
On the other hand, if you are getting along fine, offering this sensitive information is probably not worth the risk.Slide144
Should You Tell Your Kids about Your
Mental
Illness?
Research shows that if parents don’t tell children about their mental illness, children develop misinformation and worries which can be worse than the
reality.Strike a balance. There’s a fine balance between revealing the truth to your kids and overwhelming them. Prevent passing on any shameful connotation of mental illness; Discuss it openly (as is age appropriate) and without judgment.Slide145
Should You Tell Your Kids about Your
Mental Illness?
Take age and maturity into account
. How you talk to your kids will largely depend on their age and maturity level.
Be open to their questions. Your kids may have a variety of questions, especially as they get older. Teens may fear that they’ll also struggle with mental illness. Younger kids may ask if they caused the illness and wonder how they can fix it. Slide146
Should You Tell Your Kids about Your
Mental Illness?
See your talk as a learning opportunity
. Parents
with mental illness have a special opportunity to teach their kids one of life’s most important lessons: Everyone has their baggage. It’s not so important what the baggage is, but how it’s handled.Give children the language for talking about mental health, feelings, emotional wellbeing and mood. Help them understand that mental health is a vital part of health, wellbeing and family life. Stress to your kids the importance of taking good care of themselves. Talk to them about wellness, sleep, exercise and nutrition. If they’re older, you can talk about the red flags of mental illness, as well.Slide147
Should You Tell Your Kids about Your
Mental Illness?
Be reassuring
. Kids may become preoccupied with worry about their parents’ wellbeing or their own future mental
health. Reassure your kids that you love them, that you’re getting help, and “that someone will always be there to meet their needs.”Consider counseling for your kids. Counseling can help educate, build coping skills and give kids another venue for emotional support.Slide148
Disclosure at 12-Step MeetingsSlide149
The A.A. Member—
Medications & Other Drugs
“From
the earliest days of Alcoholics Anonymous it has been clear that many alcoholics have a tendency to become dependent on drugs other than alcohol. There have been tragic
incidents of alcoholics who have struggled to achieve sobriety only to develop a serious problem with a different drug. Time and time again, A.A. members have described frightening and sobriety-threatening episodes that could be related to the misuse of medication or other drugs. Experience suggests that while some prescribed medications may be safe for most nonalcoholics when taken according to a doctor’s instructions, it is possible that they may affect the alcoholic in a different way. It is often true that these substances create dependence as devastating as dependence on alcohol. It is well known that many sedatives have an action in the body similar to the action of alcohol. When these drugs are used without medical supervision, dependence can readily develop. Many A.A.s who have taken over-the-counter, nonprescription drugs have discovered the alcoholic’s tendency to misuse. Those A.A.s who have used street drugs, ranging from marijuana to heroin, have discovered the alcoholic’s tendency to become dependent on other drugs. The list goes on and will lengthen as new drugs are developed. Always consult your doctor if you think medication may be helpful or needed.”Slide150
The A.A. Member—
Medications & Other Drugs
“Note
to medical professionals: Cooperation with the professional community has been an objective of Alcoholics Anonymous since its beginnings. Professionals who work with alcoholics share a common purpose with Alcoholics Anonymous: to help the alcoholic stop drinking and lead a healthy, productive life.
As noted in the introduction, some A.A. members must take prescribed medications. However, our experience indicates that the misuse of prescription medication can threaten the achievement and maintenance of sobriety. The suggestions provided in our introduction are offered to help A.A. members find the right balance and minimize the risk of relapse.”Slide151
Friendship is a wildly underrated medication.
--Anna
Deavere Smith
actress, playwright & professor