PPT-22.7 Gluconeogenesis: Glucose Synthesis

Learning Goal Describe how glucose is synthesized from noncarbohydrate molecules Glucose is synthesized in the tissues of the liver and kidneys Tissues that use glucose as their main energy source are the brain skeletal muscles and red blood cells. C483 Spring 2013. 1. An . intermediate found in gluconeogenesis and not glycolysis is. A) 2-phosphoglycerate.. B) oxaloacetate.. C) . phosphoenolpyruvate. .. D) fructose 1,6-bisphosphate.. 2. In the Cori Cycle, _____ is transported through blood to the liver, where it is made into ________ and then ___________ for transport out of the liver.. Monosaccharides. , Disaccharides and Polysaccharides. Monomers and Polymers. A large . molecule made up of smaller units. is called a . polymer. The individual . units that make up a polymer. are called . Monosaccharides. , Disaccharides and Polysaccharides. Monomers and Polymers. A large . molecule made up of smaller units. is called a . polymer. The individual . units that make up a polymer. are called . In glycolysis, these enzymes are . Hexokinase. Phosphofructokinase. P. yruvate kinase. Phosphofructokinase is the key regulator of glycolysis in mammals. The enzyme is allosterically inhibited by ATP and allosterically stimulated by AMP.. Pratt and . Cornely. , Chapter 13. Glycolysis Expectations. Memorize/learn Figure 13.2. Know overall reaction and stages. Explain chemical logic of each step. Enzyme mechanisms presented in book. Glycolysis. Metabolism. Chapter 10: Gluconeogenesis. I. . OVERVIEW. Some tissues, such as the brain, red blood cells (RBCs), kidney medulla. , lens . and cornea of the eye, testes, and exercising muscle, require a . Part II. Dr. Kevin Ahern. Glycolysis. Summary. Glucose 2 ADP 2P. i. 2 NAD. . Yields. 2 Pyruvate 2 ATP 2 NADH 2 H. . 2 H. 2. O . Glycolysis. Fermentation in Yeast/Bacteria. Glucose. GA3P. . Parts 1-4 – Data Extraction, Quality Assessment, Synthesising Across Studies, . Completing the Analysis. Workshop: . Framework Synthesis, Meta-Ethnography and Realist Synthesis . Shared Topic: . Department . of Pediatrics, Pediatric Endocrinology, . Diabetology. and Neurology. . Provincial . Polyclinical. Hospital in Torun. . Definition. . symptom not a . disease. . too. . low. . glucose. FATE OF . PYRUVATE. MADE FROM GLYCOLYSIS. FATE OF . PYRUVATE. MADE FROM GLYCOLYSIS. Lactic . acid fermentation occurs in muscle cells when oxygen is in low . supply.. Human Lactate . dehydrogenase . M.Sc. . Zaenab. M. . Najem. Glucose metabolism . Glycolysis . is the sequence of reactions that converts glucose into pyruvate in the presence of oxygen (aerobic) or lactate in the absence of oxygen (anaerobic) with the production of ATP. . 1. FORWARD REACTION. REVERSE REACTION. D. G. o . (kJ). K. Significance. 200. 100. 50. 10. 1. 0. -1. -10. -50. -100. -200. 9x10. -36. 3x10. -18. 2x10. -9. 2x10. -2. 7x10. -1. 1. 1.5. 5x10. 1. 6x10. 8. &. The Pentose Phosphate Pathway. Dr. . Shaimaa. . Munther. . Glycogen Metabolism. A constant source of blood glucose is an absolute requirement for human life. Glucose is the greatly preferred energy source for the brain, and the required energy source for RBC and muscle, since it’s the substrate for anaerobic . ( Starch, Glycogen, Cellulose); for example of poly saccharides . . Simple types of carbohydrates such as ;Glyceraldehyde,. Dihydroxyacetone,(Triose;n=3) . .