TRANEXAMIC ACID IN TRAUMA AND TRAUMATIC BRAIN

luanne-stotts
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TRANEXAMIC ACID IN TRAUMA AND TRAUMATIC BRAIN
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TRANEXAMIC ACID IN TRAUMA AND TRAUMATIC BRAIN INJURY PATIENTS INDICATIONS FOR USE IN TRAUMA Either SBP 90 mmHg (for patients 12 years) Or HR 110 (for patients 12 years) Neither of the above but still considered to be at risk of

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TRANEXAMIC ACID IN TRAUMA AND TRAUMATIC BRAIN INJURY PATIENTS INDICATIONS FOR USE IN TRAUMA
 
Either SBP <90 mmHg (for patients > 12 years)
Or HR >110 (for patients > 12 years)
Neither of the above but still considered to be at risk of significant internal or external haemorrhage (all ages)
And within 8 hours of injury INDICATIONS FOR USE IN TRAUMATIC BRAIN INJURY
 
Has the patient had a head injury?
Has the injury occurred within the last 3 hours?
Is the GCS 12 or less?

If the answer to all three questions is yes, administer 1g Tranexamic Acid IV ASAP IF PATIENT IS FOUND TO HAVE A GCS 13-15 THEN CONSIDER
 
Does the CT scan show a traumatic brain injury?
Is it less than 3 hours since injury?

If the answer to both questions is yes, administer 1g tranexamic acid IV ASAP ADULTS
 
Loading dose 1g tranexamic acid in 100ml 0.9% sodium chloride given over 10 minutes
immediately followed by
Infusion of 1g tranexamic acid in 500ml 0.9% sodium chloride given over 8 hours CHILDREN
 
Loading dose 15mg/kg (maximum 1g) tranexamic acid in 20ml 0.9% sodium chloride given over 10 minutes, immediately followed by Infusion - see SORT Children’s Major trauma guidelines for dosing schedule of infusion CONTRA–INDICATIONS. The only absolute contra–indication is thromboembolic disease – more specifically - clinical evidence of a thrombotic disseminated intravascular coagulation.

Please see micro-guide for more information.<br>