PPT-Cholestasis of Pregnancy

Sean Heinz Epidemiology Prevalence varies throughout the world Influenced by genetic and environmental factors 07 in multiethnic populations Highest rates in South America especially Chile and among Indigenous South Americans 5 prevalence. Green-top Guideline No. 43. April 2011. Prof. of Ob, Gyn . Al Azhar University (Domiate). Prof. . Mahmoud. . Midan. . Definition. Obstetric cholestasis is a multifactorial condition of pregnancy characterised by . Liver and gastrointestinal disease. Physiological changes in pregnancy. Relaxation of smooth muscle resulting in:. decreased lower oesophageal sphincter pressure. decreased gastric peristalsis. delayed gastric emptying. Overview. Definition. Production & metabolism. Measurement of . bilirubin. – serum & urine. Approach to the patient. Broad Differential Diagnosis. Work-up for “Medical” Jaundice. Work-up if Obstructive Jaundice. Jay Hochman, mD. GI Care For Kids. August 3, 2017. Learning Objectives. Understand the causes of neonatal cholestasis. Learn about advances in diagnosis of neonatal cholestasis and appropriate use of genetic panels. ad . insorgenza. . precoce. . Lorenzo D'Antiga. Child . Health. Paediatric. . Hepatology. , . Gatroenterology. and . Transplantation. Hospital Papa Giovanni XXIII . Bergamo. Paediatric cholestasis: historical background. Cholestasis . is defined as reduced bile flow and is characterized by . elevation of . the conjugated, or direct, bilirubin fraction. . This . condition must . be distinguished . from physiological neonatal jaundice, in which the . Dr. Ashok Singh. Assistant Professor. Dept. of Pathology. INTEGRATED TEACHING. “ . Jaune. ” : Yellow. . पीलिया. Icterus. Latin. Sighting the bird was thought to cure jaundice. Jaundice. Rawashdeh. , MD, . MSc. , FRCP, FRCPCH. Professor of Pediatrics . & . Gastroenterology. Jaundice: Definition. Yellow staining of the skin and sclera by abnormally high blood levels of the bile pigment . I. ntrahepatic . C. holestasis. (PFIC 1~3). Definition. A heterogeneous group of disorders. in which . cholestasis of hepatocellular origin. often presents in the neonatal period or first year of life . 23 European Review for Medical and Pharmacological Sciences2017; 21 (1 Suppl): 23-36 F.R. PONZIANI1, S. BHOORI2, M. POMPILI1, M.A. ZOCCO1, M. BIOLATO1, G. MARRONE1, A. GASBARRINI1, V. MAZZAFERRO2, A. 62 different problems related to the fact that the protec-tive effect of the gut is breached. These are first theteria. The liver, as the target organ of these aspects ofPN-INDUCED CHOLESTASIS DEFINED Ref. GL M0005 This document is to be viewed via the CDHB Intranet only.All users must refer to the latest version from the including photocopies, may not reflect the latest version. Page 1 of 5 M 1 Intrahepatic cholestasis of pregnancy Description Intrahepatic cholestasis of pregnancy is a liver disorder that occurs in pregnant women. Cholestasis is a condition that impairs the release of a d Rawashdeh. , MD, . MSc. , FRCP, FRCPCH. Professor of Pediatrics . & . Gastroenterology. Jaundice: Definition. Yellow staining of the skin and sclera by abnormally high blood levels of the bile pigment .