PPT-HKS Tumore HKS Tumore Epigenetics in glioma

MGMT ABCB1 and ABCG2 methylation in glioma Moritz C Oberstadt PhD Tumor diseases High maligne tumors with low 5 years overall survival OS Brain tumors 1315 Stomach 1213. Antonio . Contu. / Sara . Marredda. . S.C. di Oncologia Medica. Sassari. . 25 MAGGIO 2012 . CAGLIARI. Negli ultimi vent’anni, la prognosi di molti tumori è nettamente migliorata. http://www.cancer.org. Kevin Ferriter. Mariah Minder. From Yesterday…. Do you think your brain cell and your blood cell have the same DNA sequence?. Genetics. Every cell contains all of your DNA. Not every cell expresses all of your DNA. . Cancer Immunotherapy. Immunity and Tumors. 1890s. Coley. treats patients with bacterial extracts. . 1950-1960s. Burnet and Thomas. - Immune-surveillance Hypothesis. “. Major function of the immune system is to recognize and destroy arising malignantly transformed cells. -What is epigenetics? -Epigenetics and us -Past, present, and future You Are What Your Mother Ate:What is Epigenetics?Daniel Lieber DNA is the Source of Heritable Information in the Cell organism Crea . Samudra. K. . Wijeratne. , Ph.D.. Dept. of Nutrition and Health Sciences, UNL. Processes in . Epigenetics. The . study of heritable changes in gene expression or cellular phenotype caused by mechanisms other than changes in the underlying DNA . . O. rigin. Occult Metastases. BIOLOGIA delle METASTASI. Prof. S. Berretta – Lezioni Clin. Chirurgica 2002. METASTATIC CASCADE. “ THE HALLMARK of MALIGNANT TUMOUR”. . Capacità e potenzialità di dare metastasi. http://www.knowabouthealth.com/wp-content/uploads/2010/06/mcdonalds_.jpg. http://emilyscarenhealth.wordpress.com/2011/10/04/attention-a-must-read-for-smokers/. Can “. nuture. ” change “nature” ?. Epigenetics comprises (hereditary) changes in gene expression without altering the DNA sequence . Epigenetics is a biological subdiscipline that deals with questions of development, heredity, gene regulation and evolution .  . Project . Promoter: University of Tartu. Project . Leader: . Tambet Teesalu . PhD, Visiting Professor.  . Project Partner: University of Bergen. Research Group Leader: . Rolf Bjerkvig. , PhD, Professor. 2269 patients as an antiangiogenic agent (16). The hypothesis thatthe drug should be beneficial during radiation of DIPGappears to be well supported. However, our data do notconfirm this hypothesis, t Glioma (LGG) Stephanie Rice, BS (MSIV), Abigail T. Berman, MD Michelle Alonso - Basanta , MD, PhD University of Pennsylvania October 2013 Updated by Elizabeth J. Buss, MD and Tony J. C. Wang, MD Colum Centro Congressi Roma Eventi Trevi. 11 settembre 2014. 2. NUMERO STIMATI . DI. CASI, TUTTI I TIPI . DI. CANCRO (. M+. F) . IN EUROPA. INCIDENZA. 2,445,000. MORTALITA’. 1,234,000. 6,617,411. 5 anni PREVALENZA. ‘Epi’: On top of. . Definition:. The . study of changes in organisms caused by modification of gene expression rather than alteration of the genetic code itself.. DNA. How many cell types are in the human body?. county-level socioeconomic measures. Jill S. Barnholtz-Sloan, PhD. Sally S Morley Designated Professor in Brain Tumor Research. Associate Director for Bioinformatics and Translational Informatics. Case Western Reserve University School of Medicine.