Oocyte transport and fertilization ovulated oocyte with its cumulus cells sweeps into uterine tube by tubal fimbriae and ciliated epithelium tube contracts rhythmically pushing oocyte to uterine lumen in about 4 days ID: 1010352
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1. Developmental changes during first week:
2. Oocyte transport and fertilization: ovulated oocyte with its cumulus cells, sweeps into uterine tube, by tubal fimbriae and ciliated epithelium, tube contracts rhythmically pushing oocyte to uterine lumen in about 4 days.
3. sperms ascend from vaginum ,uterus and tubes by action of flagella of mucosa of uterine cervix, contractions of uterus and tubes and sperm movement.sperms remain viable for 3 days in isthmus of uterine tube Fertilization occurs in ampulary wide lateral 1/3 of tube.
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5. preparations for fertilization Capacitation: removal of glycoprotein and seminal proteins covering acrosomal membrane. acrosomal reaction: release of acrosomal proteolytic enzymes as acrosine & trypsine-like enzymes to penetrate zona pellucida.
6. Phases of fertilization: The sperms undergo preparations.Penetration of corona radiata. Penetration of zona pellucida. Adhesion + fusion of oocyte membrane, membrane of sperm remains outside oocyte while sperm head + tail enter into oocyte cytoplasm.
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