PPT-Lab 5 –Blood, Lymphatics and the Immune Response

Gilbert Pitts PhD Joseph Schiller PhD James F Thompson PhD Objectives Examine Lymph node slide Lymphatic vessels on charts and models Blood slides Differentiate red blood cells platelets neutrophils lymphocytes monocytes eosinophils and basophils. THE IMMUNE SYSTEM. NONSPECIFIC DEFENSES AGAINST INFECTION INCLUDE THE. SKIN. MUCOUS MEMBRANES. PHAGOCYTIC CELLS. ANTIMICROBIAL PROTEINS. THE IMMUNE SYSTEM. NONSPECIFIC DEFENSE MEANS THAT THEY DON’T DISTINGUISH BETWEEN MICROBES. Founded in 2016. Location. BioHub. at . Alderley. Park (UK). Management Team. Dr.. Ir. Robert-Jan Lamers. Dr.. Masih Alam. A CRO offering specialised lab services . in the . field of immunology:. Super Awesome Powers of Cell Signaling!. Reminder - Do the Questions!. Do the questions, or Mrs. Davis will be so super sad. Plus, this stuff is AWESOME.. Immunologists. 10-11 years of schooling/training. PATH 417A. Jen Yong. Case. : . Food-borne bacterial infection. “One Too Many Hamburgers”. 10-year-old Ronnie McDonald has developed . abdominal cramps. , . bloody diarrhea. and a . low grade fever. Non-specific Immunity. Born with some immunity . Helps prevent disease. Helps slow disease progression. First line of defense. Non-specific, cont. .. Physical Barrier- . unbroken skin . Immunology. - the study of host defense mechanisms. Immunity. -. ability of the host to protect itself against foreign organisms. Resistance to disease.. Antigen (Ag)- . is a foreign substance that can elicit specific immune response (IR) when is immunogenic. The specialists who diagnose and treat immune system disorders are called . immunologists. , and the specialty itself is called . immunology. .. Phagocytes. Phagocytes are often the first immune system cells . The relationship between viruses and the immune system is much more intimate than it is for most bacteria: viruses often modify the cells within which they replicate, thereby rendering them ‘foreign’ and susceptible to attack by sensitized lymphocytes; furthermore, . Tony Serino, Ph.D.. Lymphatics: Topic Objectives. Be able to list and explain the flow of lymph and the function of its main organs. Be able to explain how lymph is generated. Be able to illustrate lymph node anatomy and explain its function immunologically. By: Brittaney Luu. The Innate Immune Response. Symptoms. The Physical Barrier. A . keratin plug . is present in non-lactating women to prevent the entry of bacteria created from the stratified squamous epithelium.. CfE. . Advanced Higher Biology. Unit . 2: . Organisms and Evolution. If you have done Higher Human Biology this is just revision!!! Use the key areas to create revision notes!. HOMEWORK: ACTIVITY G – Self Study Task – Immune response to parasites. Hypersensitivities. Hypersensitivity. Any immune response against a foreign antigen exaggerated beyond the norm. Four types. Type I (immediate). Type II (cytotoxic). Type III (immune complex–mediated). Veins and . lymphatics. Varicose Veins . are abnormally dilated, tortuous veins produced by prolonged increase in intra-luminal pressure and loss of vessel wall support.. The . superficial veins. of the leg are typically involved . Adaptive . Non-adaptive (. cell injury-----cell death). hypertrophy. Dysplasia. hyperplasia. neoplasia. Atrophy. Degeneration. Metaplasia. Necrosis, apoptosis. & gangrene. Reversible. Reversible* / Irreversible.