PDF-GENETIC RECOMBINATION INVOLVES

CHAPTER 5 PHYSICAL EXCHANGE Barbara McClintock in 1931 and then Curt Stern in 1933 demonstrated that the crossingover process in meiosis actually involves a physical exchange of DNA McClintock show. Gil . McVean. There are no new questions in population genetics. …only new types of data. Genome sequences of entire populations. Data with linkage to deep phenotype information. Data from multiple species. Meiosis and genetic diversity. Learning Goal:. Understand how meiosis contributes to genetic diversity. Group 5 - Team . Phoenix. !. UMBC. . Stephen Miller . Michelle Starz-Gaiano. Wellesley College. HORT6033. Molecular . Plant . B. reeding. Instructor: Ainong . Shi. HORT6033 web site: . http://comp.uark.edu/~ashi/MB. . Fall 2014 HORT6033. Molecular Plant Breeding. Lecture 9 . (09/22/2014). Genetic map construction. Mutation. Permanent change in the genetic material of an organism. All mutations in gametes are inheritable because they are copied during DNA replication. Somatic cell mutations occur in body cells. recF recA mutants and related strains. Cultures grown in the surface agar plates RL204;*, RL204/pJL21 protein is not limiting factor. reduced expression the other activities regulated not the same rec petercelec@gmail.com. www.imbm.sk. Linus. . Carl. . Pauling. (1901 – 1994). Nobel. . prize. 1954 – . Chemistry. 1962 – Peace. Francis. . Crick. (1916 – 2004). Nobel. . p. rize. 1962 – . McClintock, (1902–1992). An . American scientist and . cytogeneticist.  who was awarded the 1983 . Nobel Prize in . Physiology.. She received her . Ph.D. from.  . Cornell University.  in . 1927. She studied . Independent Assortment & Linkage. Genetic & Physical Maps. Lecture 1- Genetics. Madan K. Bhattacharyya, Ph.D.. Professor, Iowa State University. Adjunct Prof., Assam Agricultural University. mbhattac@iastate.edu. Wellcome. Trust Advanced Courses; Genomic Epidemiology in Africa. , . 21. st. – 26. th. June 2015. Africa . Centre for Health and Population Studies, University of KwaZulu-Natal, Durban, South Africa. Maps 1
Distance measured in Morgans (M) 2
Distance measured in Morgans (M) Physical MapsActual structure of genetic materialAt highest level DNA sequenceDistance measured in 10bp (Mbp) Genetic and cation of marker-trait associations, mapping Quantitative Trait Loci (QTL), candidate gene identi cation, basis for high-resolution genetic ne-mapping, which provide powerful tools for genetic anal Discovery. Genetic linkage was first discovered by the British. . geneticists William Bateson, Edith Rebecca Saunders and Reginald Punnett. . shortly after Mendel's laws were rediscovered. The understanding of genetic linkage was expanded by the work of Thomas Hunt Morgan. . Pairs of allelic genes may exchange chromosomal locations( genetic elements can move, both between chromosomes and within them.) by a process known as genetic recombination.. Homologous recombination . R. ecombination. 2. . Site-Specific . R. ecombination. 3. DNA . Transposition. Homologous Recombination at the Molecular Level. DNA BREAKS ARE COMMON AND INITIATE RECOMBINATION. Recombination repair DNA breaks by retrieving sequence information from undamaged DNA.